Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Cation channel activity"'
Autor:
Jeremy Hall, Michael Conlon O'Donovan, Daniel R. Weinberger, Michael John Owen, Nicholas E. Clifton, James T.R. Walters, Janet C Harwood, Leonardo Collado-Torres, Antonio F. Pardiñas, Arianna Di Florio, Peter Holmans, Emily E. Burke, Andrew E. Jaffe
Publikováno v:
Biological Psychiatry
BackgroundRecent breakthroughs in psychiatric genetics have implicated biological pathways onto which genetic risk for psychiatric disorders converges. However, these studies do not reveal the developmental time point(s) at which these pathways are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66441946abfdbc1f0edcd572297a4a7
http://europepmc.org/articles/PMC8375582
http://europepmc.org/articles/PMC8375582
Autor:
Hiromu Yawo, Shoko Hososhima, Keiichi Inoue, Hideki Kandori, Naoko Kubo, Yujiro Nagasaka, Takashi Nagata
Publikováno v:
Biophysics and Physicobiology, Vol 17 (2020)
Biophysics and Physicobiology
Biophysics and Physicobiology
Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab4cf23fcf1453e234fddcdb4207cdc
https://doi.org/10.2142/biophysico.bsj-2020007
https://doi.org/10.2142/biophysico.bsj-2020007
Publikováno v:
Neuroscience and Behavioral Physiology. 49:163-168
Channelrhodopsins are retinylidene proteins unique in their ability to generate light-gated passive ion currents across the membrane. Heterologous expression of channelrhodopsins in animal cells, most notably, neurons, enables precise millisecond-sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37517f4b9cddb81447aa200dac8568e4
https://doi.org/10.1007/s11055-019-00710-6
https://doi.org/10.1007/s11055-019-00710-6
Publikováno v:
Cell. 184(13)
Plant intracellular NLR proteins detect pathogen effectors and then form multimeric protein complexes ("resistosomes") that activate immune responses and cell death through unknown mechanisms. In this issue of Cell, Bi et al. show that the ZAR1 resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9876363c19901859cba0e2d894cd58
https://pubmed.ncbi.nlm.nih.gov/33984278
https://pubmed.ncbi.nlm.nih.gov/33984278
Autor:
Stephen G. Brohawn, Jonathan P Remis, Sonali S Mali, Savitha Sridharan, Abhay Kotecha, Ben Sorum, David M Kern, Daniel B Toso, Christopher M Hoel, Diana M. Bautista
Publikováno v:
Nat Struct Mol Biol
Nature structural & molecular biology, vol 28, iss 7
Nature Structural & Molecular Biology
Nature structural & molecular biology, vol 28, iss 7
Nature Structural & Molecular Biology
SARS-CoV-2 ORF3a is a putative viral ion channel implicated in autophagy inhibition, inflammasome activation, and apoptosis. 3a protein and anti-3a antibodies are found in infected patient tissues and plasma. 3a deletion in SARS-CoV-1 reduces viral t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592744c7f9f4aa34f4dcad1c91504653
https://europepmc.org/articles/PMC8772433/
https://europepmc.org/articles/PMC8772433/
Autor:
Véronique Picard, Guillaume Bouyer, Martin Figeac, Judith Bruge, Claude Preudhomme, Morgane Nudel, Wassim El Nemer, David Monedero Alonso, Christian Rose, Laurent Peres, Shéhérazade Sebda, Stéphane Egée
Publikováno v:
British Journal of Haematology
British Journal of Haematology, 2021, ⟨10.1111/bjh.17467⟩
British Journal of Haematology, Wiley, 2021, ⟨10.1111/bjh.17467⟩
British Journal of Haematology, 2021, ⟨10.1111/bjh.17467⟩
British Journal of Haematology, Wiley, 2021, ⟨10.1111/bjh.17467⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0065b11c4928302f972256a0cb72763
https://hal.science/hal-03242645
https://hal.science/hal-03242645
Autor:
Santosh Kumar Upadhyay, Mehak Taneja
Plant annexins are soluble proteins characterized by Ca2+-dependent as well as Ca2+-independent binding to cellular membranes. The membrane attachment or insertion of annexin proteins is dynamic and subject to environmental change. These proteins are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b8137f739a9643414da892c1219dea9
https://doi.org/10.1016/b978-0-12-821792-4.00009-6
https://doi.org/10.1016/b978-0-12-821792-4.00009-6
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 4, Iss 1, Pp n/a-n/a (2021)
Endocrinology, Diabetes & Metabolism
Endocrinology, Diabetes & Metabolism
Introduction Sex differences in brain cortical function affect cognition, behaviour and susceptibility to neural diseases, but the molecular basis of sexual dimorphism in cortical function is still largely unknown. Oestrogen and oestrogen receptors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496f6afc938a29c02bc6240653255ca2
https://doaj.org/article/77d74774a18d4467a7f2bcf1dc77ce95
https://doaj.org/article/77d74774a18d4467a7f2bcf1dc77ce95
Autor:
Jonathan Bruno, John C. Edwards
Publikováno v:
The Journal of Biological Chemistry
Variants in Apolipoprotein L1 (ApoL1) are known to be responsible for increased risk of some progressive kidney diseases among people of African ancestry. ApoL1 is an amphitropic protein that can insert into phospholipid membranes and confer anion- o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad0530af916e0a22c05318dce4e02eb
https://pubmed.ncbi.nlm.nih.gov/33380423
https://pubmed.ncbi.nlm.nih.gov/33380423
Publikováno v:
Livestock Science. 250:104605
A large number of genome-wide association studies (GWAS) in livestock, especially in dairy cows, provide favorable conditions to integrate multiple independent studies. Methods such as meta-analysis provide the identification of effective QTLs with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e143ffd7ce68831b880f4b302949267
https://doi.org/10.1016/j.livsci.2021.104605
https://doi.org/10.1016/j.livsci.2021.104605