Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Cation Transport Protein"'
1
Magnesium in Infectious Diseases in Older People
Autor: Nicola Veronese, Mario Barbagallo, Fernando Guerrero-Romero, Ligia J. Dominguez
Publikováno v: Nutrients
Nutrients, Vol 13, Iss 180, p 180 (2021)
Reduced magnesium (Mg) intake is a frequent cause of deficiency with age together with reduced absorption, renal wasting, and polypharmacotherapy. Chronic Mg deficiency may result in increased oxidative stress and low-grade inflammation, which may be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f9a628194f97df5b1841a2d9bc2e92
https://doi.org/10.3390/nu13010180
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2
Behind the Link between Copper and Angiogenesis: Established Mechanisms and an Overview on the Role of Vascular Copper Transport Systems
Autor: Emanuela Urso, Michele Maffia
Publikováno v: Journal of Vascular Research. 52:172-196
Angiogenesis critically sustains the progression of both physiological and pathological processes. Copper behaves as an obligatory co-factor throughout the angiogenic signalling cascades, so much so that a deficiency causes neovascularization to abat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6c7988d8232753f6b9d1541f502cae
https://doi.org/10.1159/000438485
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3
The DMT1 IVS4+44C>A polymorphism and the risk of iron deficiency anemia in children with celiac disease
Autor: Erasmo Miele, Alessandra Vitale, Carlo Tolone, Caterina Strisciuglio, Giulia Bellini, Bruno Nobili, Alfonso Papparella, Francesca Rossi, Francesca Punzo
Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0185822 (2017)
PLoS ONE
Background Iron deficiency anemia in celiac disease is related to impaired duodenal mucosal uptake, due to villous atrophy. Iron enters the enterocytes through an apical divalent metal transporter, DMT1. Different DMT1 transcripts have been identifie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513a1097bca69cbec447353582eb7046
http://europepmc.org/articles/PMC5638269?pdf=render
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4
A structural model of human ferroportin and of its iron binding site
Autor: Antimo Cutone, Giovanni Musci, Tiziana Persichini, Maria Carmela Bonaccorsi di Patti, Franco Felici, Giovanna Cece, Fabio Polticelli
Publikováno v: FEBS Journal. 281:2851-2860
A structural model of human ferroportin has been built using two Escherichia coli proteins belonging to the major facilitator superfamily of transporters. A potential iron binding site was identified in the inward-open conformation of the model, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64476d687c4ea9a98ee263bf28477693
https://doi.org/10.1111/febs.12825
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6
A Genomewide Screen for Tolerance to Cationic Drugs Reveals Genes Important for Potassium Homeostasis in Saccharomyces cerevisiae
Autor: Ivan Olier, Clara Navarrete, Rito Herrera, Lydie Maresova, Joaquín Ariño, Jesús Giraldo, José Ramos, Silvia Petrezsélyová, Lina Barreto, Lynne Yenush, Jorge Pérez-Valle, David Canadell, Hana Sychrová
Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Universitat Autònoma de Barcelona
[EN] Potassium homeostasis is crucial for living cells. In the yeast Saccharomyces cerevisiae, the uptake of potassium is driven by the electrochemical gradient generated by the Pma1 H +-ATPase, and this process represents a major consumer of the gra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c28409a67a3c7b47e3cb88ad40ba712
https://doi.org/10.1128/ec.05029-11
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7
Wilson's disease caused by alternative splicing and Alu exonization due to a homozygous 3039-bp deletion spanning from intron 1 to exon 2 of the ATP7B gene
Autor: Raffaele Iorio, Francesca Chiappe, Giusy Ranucci, Georgios Loudianos, Fabiola Di Dato, Eva Mameli, Maria Barbara Lepori
We describe a case of Wilson's disease (WD) diagnosed at 5 years after routine biochemical test showed increased aminotransferases. Mutation analysis of the ATP7B gene revealed a 3039-bp deletion in the homozygous state spanning from the terminal par
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3ce18b29c1dbdd030f8e326ca321e4
http://hdl.handle.net/11588/620702
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8
Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy
Autor: Ciro Indolfi, Clarice Gareri, Fabiola Marino, Michele Torella, Fiona C. Lewis, Daniele Torella, Iolanda Aquila, Domenico Cozzolino, Claudio Iaconetti, Beverley J. Henning, Giovanni Cuda, Nadia Lascar, Teresa Salvatore, Georgina M. Ellison, Roberto Torella, Carla Vicinanza, Mariangela Scalise, Ferdinando Carlo Sasso, Gianantonio Nappi
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Diabetes mellitus ( DM ) has multifactorial detrimental effects on myocardial tissue. Recently, carbonic anhydrases ( CAs ) have been shown to play a major role in diabetic microangiopathy but their role in the diabetic cardiomyopathy is s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0018dfca49d13ac4b4b8c548e46d16cc
https://pubmed.ncbi.nlm.nih.gov/24670789
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10
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2
Autor: Hugh Giovinazzo, Laura J. Janke, Cynthia S. Lancaster, Guoqing Du, Giuliano Ciarimboli, Alice A. Gibson, Alex Sparreboom, Anthony F. Shields, Guido Cavaletti, Jason A. Sprowl
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 110(27)
Oxaliplatin is an integral component of colorectal cancer therapy, but its clinical use is associated with a dose-limiting peripheral neurotoxicity. We found that the organic cation transporter 2 (OCT2) is expressed on dorsal root ganglia cells withi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772ef73e620b90e7859f1e0aa1957715
https://pubmed.ncbi.nlm.nih.gov/23776246
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