Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cathyryne K. Manner"'
Autor:
Darya Kizub, Cathyryne K. Manner, Katy Graef, Bello Abubakar, Jackson Orem, Folakemi Odedina, Mojisola Christianah Adeyeye, Gertrude Nakigudde, Kassa Ayalew, Chitkala Kalidas, Herbert Kim Lyerly, Thea Norman, Lola Fashoyin-Aje, Jamie Freedman, Jennifer Dent, Bill Cance, Julie Gralow
Publikováno v:
JCO Global Oncology, Vol , Iss 8 (2022)
Patients of African ancestry are not well-represented in cancer clinical trials despite bearing a disproportionate share of mortality both in United States and Africa. We describe key stakeholder perspectives and priorities related to bringing early-
Externí odkaz:
https://doaj.org/article/c70bdb1e2e38445683572079d0ce2509
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 4, Iss 1, p 53 (2019)
Tropical diseases, including malaria and a group of infections termed neglected tropical diseases (NTDs), pose enormous threats to human health and wellbeing globally. In concert with efforts to broaden access to current treatments, it is also critic
Externí odkaz:
https://doaj.org/article/c0a04847a29f4af883aa99063ad0141c
Autor:
Daniel Seymour, Jennifer Dent, Delaney Lake, Michelle Lee, Faruk Mohammed, Noah Hunthausen, Cathyryne K. Manner, Callie Weber, Katy M. Graef, Analise LeJeune, Joseph Hargan-Calvopina
Publikováno v:
GHTC
The African continent is facing a cancer crisis. African women experience a higher burden of a deadly form of breast cancer than women of other ethnicities. [1] African men are disproportionately impacted by prostate cancer and have poor treatment ou
Autor:
Analise LeJeune, Cathyryne K. Manner, Joseph Hargan-Calvopina, Jennifer Dent, Katy M. Graef, Noah Hunthausen, Callie Weber, Michelle Lee
Publikováno v:
GHTC
Malaria, tuberculosis, and neglected tropical diseases (neglected diseases) affect more than one billion people, mostly in the world's poorest populations, and cost developing economies billions of dollars each year. United Nations Sustainable Develo
Publikováno v:
Tropical Medicine and Infectious Disease
Schistosomiasis is an acute and chronic disease that affects over 200 million people worldwide, and with over 700 million people estimated to be at risk of contracting this disease, it is a pressing issue in global health. However, research and devel
Autor:
Lesley G. Ellies, Michael Fishman, Carol L. MacLeod, Jeanine Kleeman, Robert D. Cardiff, Joy Hardison, Cathyryne K. Manner, Jeannie E. Maglione
Publikováno v:
International Journal of Cancer. 106:1-7
Nitric oxide (NO) and its metabolites are implicated in carcinogenesis and metastasis. Both stimulatory and inhibitory effects of NO have been reported in relation to breast cancer and its role in the development of malignancies and metastasis remain
CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes
Publikováno v:
Journal of Neurochemistry. 85:476-482
We have previously demonstrated that genetic ablation of cationic amino acid transporter 2 (Cat2) significantly inhibits nitric oxide (NO) production by inducible nitric oxide synthase (iNOS) in activated macrophages. Here we report that iNOS activit
Publikováno v:
Journal of Biological Chemistry. 276:15881-15885
The aberrant production of nitric oxide (NO) contributes to the pathogenesis of diseases as diverse as cancer and arthritis. Sustained NO production via the inducible enzyme, nitric-oxide synthase 2 (NOS2), requires extracellular arginine uptake. Thr
CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes
Publikováno v:
Journal of neurochemistry. 85(2)
We have previously demonstrated that genetic ablation of cationic amino acid transporter 2 (Cat2) significantly inhibits nitric oxide (NO) production by inducible nitric oxide synthase (iNOS) in activated macrophages. Here we report that iNOS activit
Publikováno v:
Nitric oxide : biology and chemistry. 7(4)
High-output nitric oxide (NO) production by nitric oxide synthase 2 (NOS2) contributes to normal cellular processes and pathophysiological conditions. The transport of l -arginine, the substrate for NOS2, is required for sustained NO production by NO