Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Cathy Steel"'
Autor:
Benjamin F Arnold, Mark J van der Laan, Alan E Hubbard, Cathy Steel, Joseph Kubofcik, Katy L Hamlin, Delynn M Moss, Thomas B Nutman, Jeffrey W Priest, Patrick J Lammie
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005616 (2017)
BACKGROUND:Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measure
Externí odkaz:
https://doaj.org/article/e157128c674b4dd1893dcc7071c574d1
Autor:
Allison Golden, Eric J Stevens, Lindsay Yokobe, Dunia Faulx, Michael Kalnoky, Roger Peck, Melissa Valdez, Cathy Steel, Potochoziou Karabou, Méba Banla, Peter T Soboslay, Kangi Adade, Afework H Tekle, Vitaliano A Cama, Peter U Fischer, Thomas B Nutman, Thomas R Unnasch, Tala de los Santos, Gonzalo J Domingo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004292 (2016)
Serological assays for human IgG4 to the Onchocerca volvulus antigen Ov16 have been used to confirm elimination of onchocerciasis in much of the Americas and parts of Africa. A standardized source of positive control antibody (human anti-Ov16 IgG4) w
Externí odkaz:
https://doaj.org/article/fc119ed08a81444787e314d1af42cc83
Autor:
Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004579 (2015)
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate in
Externí odkaz:
https://doaj.org/article/f414162c63a541f0b9c81b17912306a4
Autor:
Allison Golden, Cathy Steel, Lindsay Yokobe, Emily Jackson, Rebecca Barney, Joseph Kubofcik, Roger Peck, Thomas R Unnasch, Thomas B Nutman, Tala de los Santos, Gonzalo J Domingo
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69231 (2013)
Onchocerciasis is a neglected tropical disease caused by infection with the parasite Onchocerca volvulus (Ov). An estimated 180 million people are at risk for Ov infection, and 37 million people are infected, mostly in Africa. A lateral flow-based as
Externí odkaz:
https://doaj.org/article/23e97eb719cf4d11b1abc37c83a93431
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1940 (2012)
Antibody (Ab) to the Wuchereria bancrofti (Wb) infective larval (L3) antigen Wb123, using a Luciferase Immunoprecipitation System (LIPS) assay, has been shown to be a species-specific, early marker of infection developed for potential use as a survei
Externí odkaz:
https://doaj.org/article/bb80b5253a7f45ce84d93ea22443a199
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 2, p e1527 (2012)
Human filarial infection is characterized by downregulated parasite-antigen specific T cell responses but distinct differences exist between patients with longstanding infection (endemics) and those who acquired infection through temporary residency
Externí odkaz:
https://doaj.org/article/40ed9cae3bbc4da3a364825840a17a11
Autor:
Cathy Steel, Thomas B Nutman
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19197 (2011)
Chronic lymphatic filarial (LF) infection is associated with suppression of parasite-specific T cell responses that persist even following elimination of infection. While several mechanisms have been implicated in mediating this T cell specific downr
Externí odkaz:
https://doaj.org/article/464c2d99efd441c39ce1d7cfd815f2e7
Autor:
Lindsay Yokobe, Allison Golden, Cathy Steel, Gonzalo J. Domingo, Thomas B. Nutman, Tala de los Santos, Eric Stevens
Publikováno v:
Clinical and Vaccine Immunology. 22:896-901
Elimination programs for Wuchereria bancrofti and Onchocerca volvulus are in critical need of sensitive, specific, and point-of-contact (POC) tools that can be used for surveillance years beyond cessation of mass drug administration when infection in
Publikováno v:
Journal of Infectious Diseases. 212:684-693
BACKGROUND Elimination of onchocerciasis and lymphatic filariasis is targeted for 2020. Given the coincident Loa loa infections in Central Africa and the potential for drug resistance development, the need for new microfilaricides and macrofilaricide
Autor:
Melissa Valdez, Thomas R. Unnasch, Eric Stevens, Allison Golden, Meba Banla, Thomas B. Nutman, Roger Peck, Cathy Steel, Potochoziou K. Karabou, Gonzalo J. Domingo, Dunia Faulx, Kangi Adade, Peter T. Soboslay, Peter Fischer, Afework H. Tekle, Lindsay Yokobe, Tala de los Santos, Michael Kalnoky, Vitaliano Cama
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004292 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Serological assays for human IgG4 to the Onchocerca volvulus antigen Ov16 have been used to confirm elimination of onchocerciasis in much of the Americas and parts of Africa. A standardized source of positive control antibody (human anti-O