Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Cathy Shen"'
A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort
Autor:
Shih-Pin Chen, Chia-Lin Hsu, Ting-Huei Chen, Li-Ling Hope Pan, Yen-Feng Wang, Yu-Hsiang Ling, Hsueh-Chen Chang, Yi-Ming Chen, Cathy Shen-Jang Fann, Shuu-Jiun Wang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The contributing genetic factors of vertigo remain poorly characterized, particularly in individuals of non-European ancestries. Here we show the genetic landscape of vertigo in an Asian population-based cohort. In a two-stage genome-wide as
Externí odkaz:
https://doaj.org/article/3527fd0cf64442f292eb0dc0cb712edc
Publikováno v:
iScience, Vol 27, Iss 7, Pp 109815- (2024)
Summary: Metabolic syndrome (MetS) is a collection of cardiovascular risk factors; however, the high prevalence and heterogeneity impede effective clinical management. We conducted unsupervised clustering on individuals from UK Biobank to reveal endo
Externí odkaz:
https://doaj.org/article/00d50dbe827649a48f36ee0c74a63e74
Autor:
Cheng-Ting Lee, Wen-Hao Tsai, Chien-Ching Chang, Pei-Chun Chen, Cathy Shen-Jang Fann, Hsueh-Kai Chang, Shih-Yao Liu, Mu-Zon Wu, Pao-Chin Chiu, Wen-Ming Hsu, Wei-Shiung Yang, Ling-Ping Lai, Wen-Yu Tsai, Shi-Bing Yang, Pei-Lung Chen
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveCongenital hyperinsulinism (CHI) is a group of clinically and genetically heterogeneous disorders characterized by dysregulated insulin secretion. The aim of the study was to elucidate genetic etiologies of Taiwanese children with the most s
Externí odkaz:
https://doaj.org/article/1245d9fc0f6545668f7be7e04ecc5a60
Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan
Autor:
Shih-Pin Chen, Chia-Lin Hsu, Yen-Feng Wang, Fu-Chi Yang, Ting-Huei Chen, Jia-Hsin Huang, Li-Ling Hope Pan, Jong-Ling Fuh, Hsueh-Chen Chang, Yi-Lun Lee, Hung-Ching Chang, Ko-Han Lee, Yu-Chuan Chang, Cathy Shen-Jang Fann, Shuu-Jiun Wang
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Cluster headache is a highly debilitating neurological disorder with considerable inter-ethnic differences. Genome-wide association studies (GWAS) recently identified replicable genomic loci for cluster headache in Europeans, but
Externí odkaz:
https://doaj.org/article/07c09c1eec7b4777a506899076130c1e
Autor:
Yun-Jin Jiang, Cathy Shen-Jang Fann, Jong-Ling Fuh, Ming-Yi Chung, Hui-Ying Huang, Kuo-Chang Chu, Yen-Feng Wang, Chia-Lin Hsu, Lung-Sen Kao, Shih-Pin Chen, Shuu-Jiun Wang
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain unclear. Objectives To identify the genetic variants of restless legs syndrome in migraineurs and to investigate their
Externí odkaz:
https://doaj.org/article/a3f05d93c4f7474295d02737a542ed6f
Autor:
Patricia Soriano Roque, Carolina Thörn Perez, Mehdi Hooshmandi, Calvin Wong, Mohammad Javad Eslamizade, Shilan Heshmati, Nicole Brown, Vijendra Sharma, Kevin C. Lister, Vanessa Magalie Goyon, Laura Neagu-Lund, Cathy Shen, Nicolas Daccache, Hiroaki Sato, Tamaki Sato, Jeffrey S. Mogil, Karim Nader, Christos G. Gkogkas, Mihaela D. Iordanova, Masha Prager-Khoutorsky, Heidi M. McBride, Jean-Claude Lacaille, Linda Wykes, Thomas Schricker, Arkady Khoutorsky
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Repeated or prolonged, but not short-term, general anesthesia during the early postnatal period causes long-lasting impairments in memory formation in various species. The mechanisms underlying long-lasting impairment in cognitive function are poorly
Externí odkaz:
https://doaj.org/article/a714889051cb4d529be111104342892a
Autor:
Lawrence Shih-Hsin Wu, Ming-Chyi Huang, Cathy Shen-Jang Fann, Hsien-Yuan Lane, Chian-Jue Kuo, Wei-Che Chiu, Pui-Yan Kwok, Andrew Tai-Ann Cheng
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The search for susceptibility genes underlying the heterogeneous bipolar disorder has been inconclusive, often with irreproducible results. There is a hope that narrowing the phenotypes will increase the power of genetic analysis. Early-onse
Externí odkaz:
https://doaj.org/article/eff9e20975a84a71b407fc450ece2157
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Many single nucleotide polymorphisms (SNPs) have been reported to be associated with migraine susceptibility. However, evidences for their associations with migraine endophenotypes or subtypes are scarce. We aimed to investigate t
Externí odkaz:
https://doaj.org/article/f2c9202349ae4541b5bf4eaa0198bec9
Autor:
Yu-Li Liu, Sheng-Chang Wang, Hai-Gwo Hwu, Cathy Shen-Jang Fann, Ueng-Cheng Yang, Wei-Chih Yang, Pei-Chun Hsu, Chien-Ching Chang, Chun-Chiang Wen, Jyy-Jih Tsai-Wu, Tzung-Jeng Hwang, Ming H Hsieh, Chen-Chung Liu, Yi-Ling Chien, Chiu-Ping Fang, Stephen V Faraone, Ming T Tsuang, Wei J Chen, Chih-Min Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150435 (2016)
D-amino acid oxidase (DAO) has been reported to be associated with schizophrenia. This study aimed to search for genetic variants associated with this gene. The genomic regions of all exons, highly conserved regions of introns, and promoters of this
Externí odkaz:
https://doaj.org/article/69b7f3d86fde43959e8a203b2ea93f58
Publikováno v:
Journal of the Formosan Medical Association, Vol 108, Iss 4, Pp 301-309 (2009)
The Val108/158 Met (rs4680) single nucleotide polymorphism (SNP) in the catechol-O-methyltransferase (COMT) gene contributes to genetic susceptibility to schizophrenia, which is specifically related to impairments in executive functioning. A differen
Externí odkaz:
https://doaj.org/article/7425cc88d9f949f1b118a38bfe3c38c6