Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Cathy S. Wang"'
Autor:
Ava P. Amini, Jesse D. Kirkpatrick, Cathy S. Wang, Alex M. Jaeger, Susan Su, Santiago Naranjo, Qian Zhong, Christina M. Cabana, Tyler Jacks, Sangeeta N. Bhatia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The activity of multiple enzymes is dysregulated in cancer, but this cannot always be measured through enzyme expression. Here, the authors develop methods to measure protease activity across the organism, tissue, and single cell scales, and identify
Externí odkaz:
https://doaj.org/article/5a1de31fec07440a8a18a30ec793bde0
Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients
Autor:
Michael Ghermezi, Mingjie Li, Suzie Vardanyan, Nika Manik Harutyunyan, Jillian Gottlieb, Ariana Berenson, Tanya M. Spektor, Claudia Andreu-Vieyra, Sophia Petraki, Eric Sanchez, Kyle Udd, Cathy S. Wang, Regina A. Swift, Haiming Chen, James R. Berenson
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
B-cell maturation antigen is expressed on plasma cells. In this study, we have identified serum B-cell maturation antigen as a novel biomarker that can monitor and predict outcomes for multiple myeloma patients. Compared to healthy donors, patients w
Externí odkaz:
https://doaj.org/article/0b663bd3368b4fe5b3a477549ec2782f
Publikováno v:
ACS Omega. 7:24292-24301
Analyzing the activity of proteases and their substrates is critical to defining the biological functions of these enzymes and to designing new diagnostics and therapeutics that target protease dysregulation in disease. While a wide range of database
Autor:
James R. Berenson, Tanya M. Spektor, George Y. Tang, Kevin DeCorso, Kyle A. Udd, Colin Xie, Jasmin Cao, Christian E. Casas, Camilia M. Soof, Tiffany Lee, Cathy S. Wang, Eric Sanchez, Mingjie Li, Haiming Chen
Evaluation of AKT signaling pathway in primary MM cells treated with a TRAF6dn inhibitory peptide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8801a64eff703eb94d31d78d199cfa69
https://doi.org/10.1158/1541-7786.22512148.v1
https://doi.org/10.1158/1541-7786.22512148.v1
Autor:
James R. Berenson, Tanya M. Spektor, George Y. Tang, Kevin DeCorso, Kyle A. Udd, Colin Xie, Jasmin Cao, Christian E. Casas, Camilia M. Soof, Tiffany Lee, Cathy S. Wang, Eric Sanchez, Mingjie Li, Haiming Chen
Cloning of the pLenti6.2-hTRAF6dn vector. The TRAF6dn cDNA was cloned into PCRII TOPO vector to produce a 167-amino acid peptide and then sub-cloned into a pLenti6.2 expression vector (pLenti6.2-hTRAF6dn).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19679d20f494fc61321b86c2457a2fac
https://doi.org/10.1158/1541-7786.22512154
https://doi.org/10.1158/1541-7786.22512154
Autor:
James R. Berenson, Tanya M. Spektor, George Y. Tang, Kevin DeCorso, Kyle A. Udd, Colin Xie, Jasmin Cao, Christian E. Casas, Camilia M. Soof, Tiffany Lee, Cathy S. Wang, Eric Sanchez, Mingjie Li, Haiming Chen
TRAF6dn FITC-labeled peptide cultured with MM cell lines for 72 hours and monitored FITC positive MM cells using immunofluorescent microscopy (20X).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9b8aee7389f17cee5f19c2f68d6136
https://doi.org/10.1158/1541-7786.22512151
https://doi.org/10.1158/1541-7786.22512151
Autor:
James R. Berenson, Tanya M. Spektor, George Y. Tang, Kevin DeCorso, Kyle A. Udd, Colin Xie, Jasmin Cao, Christian E. Casas, Camilia M. Soof, Tiffany Lee, Cathy S. Wang, Eric Sanchez, Mingjie Li, Haiming Chen
TNF receptor–associated factor 6 (TRAF6) has been implicated in polyubiquitin-mediated IL1R/TLR signaling through activation of IκB kinase (IKK) to regulate the NF-κB and JNK signaling pathways. Here, TRAF6 protein was determined to be overexpres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8408e5b06810fd3957289c639e48dd6
https://doi.org/10.1158/1541-7786.c.6540145.v1
https://doi.org/10.1158/1541-7786.c.6540145.v1
Autor:
Benjamin R Freedman, Raphael S Knecht, Yann Tinguely, G. Ege Eskibozkurt, Cathy S. Wang, David J Mooney
Publikováno v:
Acta Biomaterialia. 143:63-71
Aging is the largest risk factor for Achilles tendon associated disorders and rupture. Although Achilles tendon macroscale elastic properties are suggested to decline with aging, less is known about the effect of maturity and aging on multiscale visc
Autor:
Ning Xu, Erin Yu, Nicole Ng, Mingjie Li, Sean Bujarski, Ava Hekmati, Isabella Nassir, Tara Hekmati, Janna Yu, David Daniely, Cathy S. Wang, Clara Kim, Haiming Chen, James R. Berenson
Publikováno v:
Hematological oncologyREFERENCES.
We hypothesized that ruxolitinib may inhibit the immune checkpoint protein, B7H3; and, thus, investigated its effects on this immune inhibitor using multiple myeloma (MM) cell lines, bone marrow (BM) mononuclear cells from MM patients and human MM LA
Autor:
Ava P. Soleimany, Cathy S Wang, Santiago Naranjo, Qian Zhong, Tyler Jacks, Christina M Cabana, Susan Su, Jesse D. Kirkpatrick, Alex M. Jaeger, Sangeeta N. Bhatia
Diverse processes in cancer are mediated by enzymes, which most proximally exert their function through their activity. Methods to quantify enzyme activity, rather than just expression, are therefore critical to our ability to understand the patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a3ea128f5a87424c88cae70086d292
https://doi.org/10.1101/2021.11.11.468288
https://doi.org/10.1101/2021.11.11.468288