Výsledky vyhledávání - "Cathy M. Mueller"

Role of regenerating islet-derived proteins in inflammatory bowel disease

Autor: Alexander Schwartzman, Chongmin Huan, Peiqi Ou, Vladimir Zinsou, Nicholas E Tan, Jodi-Ann Edwards, Sean Roudnitsky, Nadlie Toussaint, Michelle Sagal, Cathy M. Mueller, Lisa Dresner, Albert Stanek

Publikováno v: World Journal of Gastroenterology

Inflammatory bowel disease (IBD) is an inflammatory disorder of the gastrointestinal tract that affects millions of patients worldwide. It has a complex and multifactorial etiology leading to excessive exposure of intestinal epithelium to microbial a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bece98bae8024c993d63fb6d343788
https://doi.org/10.3748/wjg.v26.i21.2702

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Loss of Reg proteins' protection of islet β cells in chronic pancreatitis: A potential mechanism for the pathogenesis of type 3c diabetes

Autor: Sue Dong, Joshua Zhang, Peiqi Ou, Rainer W.G. Gruessner, Ramy Abdel-Naby, Chongmin Huan, Albert Stanek, Cathy M. Mueller

Publikováno v: Current Opinion in Endocrine and Metabolic Research. 5:21-28

Type 3c diabetes mellitus (T3cDM) is a type of pancreatogenic diabetes. This form of diabetes has been significantly underappreciated, but is now receiving increased attention because of the recent recognition of its high incidence in chronic pancrea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f733005059c4b6ac3b079d9156369e2
https://doi.org/10.1016/j.coemr.2019.02.005

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

Autor: Kaylene Barrera, Devon John, Cathy M. Mueller, Chongmin Huan, Antonio E. Alfonso, Kei Okochi, Zuzanna Niewiadomska, Peiqi Ou, Albert Stanek, Scott Tenner

Publikováno v: World Journal of Gastrointestinal Pathophysiology

Acute pancreatitis (AP) is an inflammatory disorder of pancreatic tissue initiated in injured acinar cells. Severe AP remains a significant challenge due to the lack of effective treatment. The widely-accepted autodigestion theory of AP is now facing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3f7309117d9d476f638be8a597a82d
https://doi.org/10.4291/wjgp.v9.i2.37

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Pancreatic Reg I Binds MKP-1 and Regulates Cyclin D in Pancreatic-Derived Cells

Autor: Cathy M. Mueller, Hong Zhang, Michael E. Zenilman

Publikováno v: Journal of Surgical Research. 150:137-143

Background The pancreatic regenerating (reg I) gene and its protein product are derived from acinar cells and are mitogenic to β- and ductal cells. We studied the mechanism of this mitogenic response. Materials and methods ARIP (rat ductal) and RIN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e88350cfdf05167fc13f7231a2d8969
https://doi.org/10.1016/j.jss.2008.03.047

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Immunoglobulin E antibodies from pancreatic cancer patients mediate antibody-dependent cell-mediated cytotoxicity against pancreatic cancer cells

Autor: M. Hagler, Cathy M. Mueller, Matthew R. Pincus, Martin H. Bluth, Michael E. Zenilman, Joelle Pierre, Tamar A. Smith-Norowitz, Wilbur B. Bowne, Sophia L. Fu

Publikováno v: Clinical and Experimental Immunology. 153:401-409

Summary In addition to allergy and parasitic infections, immunoglobulin E (IgE) has been shown recently to possess anti-viral and anti-cancer effects. We investigated serum levels of IgE, its low-affinity receptor, soluble CD23 (sCD23) in patients wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941cb8979e3b90f14eeb188318759916
https://doi.org/10.1111/j.1365-2249.2008.03726.x

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Mutational Characterization of Pancreatitis-Associated Protein 2 Domains Involved in Mediating Cytokine Secretion in Macrophages and the NF-κB Pathway

Autor: Cathy M. Mueller, Domenico Viterbo, Michael E. Zenilman, Martin H. Bluth

Publikováno v: The Journal of Immunology. 181:1959-1968

Pancreatitis-associated protein 2 (PAP2) is a member of the Reg3 gene family and is classified as a group 7 C-type lectin-like protein. In rats, each of the three PAP isoforms has independent immunologic functional effects on macrophages. We have pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bdb6fcc8a19675620e1c7d1b32f8fe
https://doi.org/10.4049/jimmunol.181.3.1959

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Sophorolipids Improve Sepsis Survival: Effects of Dosing and Derivatives

Autor: Vishal Shah, Sophia L. Fu, Cathy M. Mueller, Michael E. Zenilman, Albert Stanek, Joelle Pierre, Martin H. Bluth, Richard A. Gross, Sabine R. Wallner, Maja Nowakowski, Robert Schulze, Jeremy Weedon, Rosemarie E. Hardin

Publikováno v: Journal of Surgical Research. 142:314-319

Introduction. Sophorolipids, a family of natural and easily chemo-enzymatically modified microbial glycolipids, are promising modulators of the immune response. We have previously demonstrated that sophorolipids mediate anti-inflammatory effects, inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aa86d54866871ba53a1abe4a017094
https://doi.org/10.1016/j.jss.2007.04.025

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Pancreatic elastase is proven to be a mannose-binding protein—implications for the systemic response to pancreatitis

Autor: Yin Yao Lin, Cathy M. Mueller, Hong Zhang, Emad Kandil, Michael E. Zenilman, Sameer A. Patel

Publikováno v: Surgery. 133:678-688

Background. Mannose-binding proteins (MBPs) have been isolated from serum, liver, lung, and kidney and are believed to play an important role in first-line host defense during acute phase inflammatory response. Because of the inflammatory nature of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b5b4a2d67f8ae0f397fc8ef21b183c
https://doi.org/10.1067/msy.2003.175

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