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pro vyhledávání: '"Cathy Korsgren"'
Autor:
Narla Mohandas, Carlo Brugnara, Kathryn M. John, Babette Gwynn, Hitesh K. Jindel, Luanne L. Peters, Cathy Korsgren, Michael Cho, Samuel E. Lux, Carl M. Cohen, David E. Golan
Publikováno v:
Journal of Clinical Investigation. 103:1527-1537
Protein 4.2 is a major component of the red blood cell (RBC) membrane skeleton. We used targeted mutagenesis in embryonic stem (ES) cells to elucidate protein 4.2 functions in vivo. Protein 4. 2-null (4.2(-/-)) mice have mild hereditary spherocytosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0708b69b70cf3663ce470f5be42bd41c
https://doi.org/10.1172/jci5766
https://doi.org/10.1172/jci5766
Publikováno v:
Blood. 80:523-529
Protein 4.2 is a major red blood cell (RBC) protein that interacts with the band 3 protein and with ankyrin. Inherited deficiencies of this protein are associated with spherocytic hemolytic anemia, but the molecular basis of this defect is unknown. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afa6c41514e214f35f4a26cc6a58112
https://doi.org/10.1182/blood.v80.2.523.bloodjournal802523
https://doi.org/10.1182/blood.v80.2.523.bloodjournal802523
Publikováno v:
Genomics. 42(3)
Previous studies identified the gene encoding the erythrocyte membrane protein 4.2 (Epb4.2) as a candidate for the mouse mutation pallid (pa); Epb4.2 genetically colocalized near pa on mouse Chromosome 2, and a truncated Epb4.2 transcript was present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91629d8d66e4d093d12e7a59807732ad
https://pubmed.ncbi.nlm.nih.gov/9205130
https://pubmed.ncbi.nlm.nih.gov/9205130