Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cathy J. Spangler"'
Autor:
Cathy J. Spangler, Aleksandra Skrajna, Caroline A. Foley, Anh Nguyen, Gabrielle R. Budziszewski, Dalal N. Azzam, Eyla C. Arteaga, Holly C. Simmons, Charlotte B. Smith, Nathaniel A. Wesley, Emily M. Wilkerson, Jeanne-Marie E. McPherson, Dmitri Kireev, Lindsey I. James, Stephen V. Frye, Dennis Goldfarb, Robert K. McGinty
Publikováno v:
Nature Chemical Biology. 19:624-632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92720ce51947090d9ebe2b31e532414
https://doi.org/10.1038/s41589-023-01256-y
https://doi.org/10.1038/s41589-023-01256-y
Autor:
Gabrielle R Budziszewski, Yani Zhao, Cathy J Spangler, Katarzyna M Kedziora, Michael R Williams, Dalal N Azzam, Aleksandra Skrajna, Yuka Koyama, Andrew P Cesmat, Holly C Simmons, Eyla C Arteaga, Joshua D Strauss, Dmitri Kireev, Robert K McGinty
Publikováno v:
Nucleic Acids Research. 50:4355-4371
A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine–threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) along with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4fc712a694ff79d54241e2704864b6
https://doi.org/10.1093/nar/gkac198
https://doi.org/10.1093/nar/gkac198
Autor:
Andrew P. Cesmat, Robert K. McGinty, Qi Zhang, Cathy J. Spangler, Joshua D. Strauss, Pengda Liu, Joshua A. Boyer
Publikováno v:
Science
Saving a host cell from itself A fundamental mammalian defense mechanism against pathogens and damaged cellular DNA is to recognize DNA fragments in the cytosol and trigger an inflammatory response. The cyclic guanosine monophosphate–adenosine mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b04a141b630f7cdc72ca49af2639e5
https://doi.org/10.1126/science.abd0609
https://doi.org/10.1126/science.abd0609
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
Autor:
Xiaokang Yan, Jeanette Gowen Cook, Aleksandra Skrajna, Dennis Goldfarb, Emily H. Barbour, Robert K. McGinty, Nathaniel A. Hathaway, Katarzyna M. Kedziora, Emily M. Cousins, Nicholas G. Brown, Michael B. Major, Cathy J. Spangler, Gavin D. Grant
Publikováno v:
Nucleic Acids Research
Nuclear proteins bind chromatin to execute and regulate genome-templated processes. While studies of individual nucleosome interactions have suggested that an acidic patch on the nucleosome disk may be a common site for recruitment to chromatin, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5ea6c5d34fc55e0c451d1bf0933821
https://doi.org/10.1093/nar/gkaa544
https://doi.org/10.1093/nar/gkaa544
Autor:
Cathy J. Spangler, Robert K. McGinty
Publikováno v:
Methods Mol Biol
Histone Methyltransferases ISBN: 9781071624807
Histone Methyltransferases ISBN: 9781071624807
Cryogenic electron microscopy (cryo-EM) has recently emerged as an optimal technique for the determination of histone methyltransferase-nucleosome complex structures. Histone methyltransferases are a group of enzymes that post-translationally methyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206eb0d7ccb8c703b2d9a0cb4357ef4c
https://europepmc.org/articles/PMC10202144/
https://europepmc.org/articles/PMC10202144/
Autor:
Katarzyna M. Kedziora, Yani Zhao, Robert K. McGinty, Cathy J. Spangler, Gabrielle R Budziszewski
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a979d8767d3607a9ade3ddbd3381fc2b
https://doi.org/10.1096/fasebj.2021.35.s1.03093
https://doi.org/10.1096/fasebj.2021.35.s1.03093
Autor:
Cathy J. Spangler, Satya P. Yadav, Dongxu Li, Carinne N. Geil, Charlotte B. Smith, Gang Greg Wang, Tae-Hee Lee, Robert K. McGinty
Publikováno v:
Cell Reports. 38:110369
DOT1L methylates histone H3 lysine 79 during transcriptional elongation and is stimulated by ubiquitylation of histone H2B lysine 120 (H2BK120ub) in a classical trans-histone crosstalk pathway. Aberrant genomic localization of DOT1L is implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45039034e72b189a3d4606d573a0dab
https://doi.org/10.1016/j.celrep.2022.110369
https://doi.org/10.1016/j.celrep.2022.110369
Autor:
Robert K. McGinty, Andrew P. Cesmat, Cathy J. Spangler, Joshua D. Strauss, Joshua A. Boyer, Qi Zhang, Pengda Liu
Publikováno v:
Biophysical Journal. 120:7a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::567d551daa8493121370e92e4b525e86
https://doi.org/10.1016/j.bpj.2020.11.306
https://doi.org/10.1016/j.bpj.2020.11.306