Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Cathy Huntoon"'
1
Inhibition of Interleukin-1-stimulated NF-κB RelA/p65 Phosphorylation by Mesalamine Is Accompanied by Decreased Transcriptional Activity
Autor: David J. McKean, James J. Lipsky, William J. Sandborn, Laurence J. Egan, Dennis C. Mays, M G Pike, Michael P. Bell, Cathy Huntoon
Publikováno v: Journal of Biological Chemistry. 274:26448-26453
Nuclear factor kappaB (NF-kappaB) is an inducible transcription factor that regulates genes important in immunity and inflammation. The activity of NF-kappaB is highly regulated: transcriptionally active NF-kappaB proteins are sequestered in the cyto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9514579c02dac9c66a2080e7183a26ea
https://doi.org/10.1074/jbc.274.37.26448
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2
Dual signal transduction through delta opioid receptors in a transfected human T-cell line
Autor: David J. McKean, Burt M. Sharp, Kathy McAllen, Nahid A. Shahabi, Wyrta Heagy, Cathy Huntoon, Michael A. Bell
Publikováno v: Proceedings of the National Academy of Sciences. 93:8294-8299
Opiates are known to function as immunomodulators, in part by effects on T cells. However, the signal transduction pathways mediating the effects of opiates on T cells are largely undefined. To determine whether pathways that regulate free intracellu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049ba7073c4fc6e96593f1433c728958
https://doi.org/10.1073/pnas.93.16.8294
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3
Substitution of class II α chain polymorphic residues defines location of Akαserologic epitopes and alters association between αβ and li polypeptides
Autor: Cathy Huntoon, Carol Chase, Michael P. Bell, David J. McKean, Kathy L. Schreiber, J M Buerstedde, Bing-Yuan Wei, Allan E. Nilson
Publikováno v: International Immunology. 6:297-305
Structure-function studies of the MHC class II alpha chain have been performed by constructing a panel of A alpha k cDNA genes with one or more d allele substitutions at each polymorphic residue of the alpha 1 domain. The altered genes (A alpha k*) w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39600185f56c4eba1e1231a109f6e398
https://doi.org/10.1093/intimm/6.2.297
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4
Ligand-induced desensitization of interleukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes
Autor: David J. McKean, Michael P. Bell, Cathy Huntoon
Publikováno v: The Journal of Experimental Medicine
Although interleukin 1 (IL-1) receptor signaling events in T helper lymphocytes are incompletely characterized, events associated with translocation of the transcription factor NF-kappa B are receptor-proximal assays of ligand-initiated responses. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1648eeff636748f0e1f1ca643d5280c3
https://pubmed.ncbi.nlm.nih.gov/7931065
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