Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cathy Housman"'
Autor:
Keith C. Cheng, Stephen I. Goodman, Ian A. Simpson, Russell E. Jacobs, James P. O'Callaghan, Michael Woontner, Jelena Lazovic, Cathy Housman, James R. Connor, William J. Zinnanti, Kathryn F. LaNoue
Publikováno v:
Journal of Clinical Investigation. 117:3258-3270
Glutaric acidemia type I (GA-I) is an inherited disorder of lysine and tryptophan metabolism presenting with striatal lesions anatomically and symptomatically similar to Huntington disease. Affected children commonly suffer acute brain injury in the
Publikováno v:
Developmental Brain Research. 152:143-152
Acute morphologic changes of brain due to chemically induced seizures are studied in developing rabbits. Accordingly, rabbits of postnatal days 6 and 7 (p6–7) and p10–12 are injected with a single dose of 1–6 mg/kg kainic acid (KA) intraperiton
Autor:
Jelena Lazovic, William J. Zinnanti, Lawrence Steinman, David A. Antonetti, James R. Connor, David M. Koeller, Cathy Housman
Publikováno v:
Acta Neuropathologica Communications
Background Metabolic stroke is the rapid onset of lasting central neurological deficit associated with decompensation of an underlying metabolic disorder. Glutaric aciduria type I (GA1) is an inherited disorder of lysine and tryptophan metabolism pre
Publikováno v:
Developmental Brain Research. 113:83-95
The present investigation was designed to study the effect of chemically induced seizures on cerebral hypoxic–ischemic (HI) damage in immature animals. Accordingly, cerebral HI was produced in 7-day postnatal (p7) rats and p13 rats by combined unil
Publikováno v:
Acta Neuropathologica. 90:375-386
The sequential evolution of neuropathologic changes was studied in an immature model of cerebral hypoxia-ischemia. Accordingly, 7-day postnatal rats were subjected to unilateral common carotid artery ligation combined with 2 h of hypoxia (breathing i
Publikováno v:
Acta Neuropathologica. 81:578-587
This study was undertaken to determine: (a) the duration of hypoxia required to produce brain damage in immature rats with unilateral carotid artery ligation (Levine technique); (b) the regions of immature brain most vulnerable to hypoxia-ischemia (H
Publikováno v:
Acta neuropathologica. 87(6)
We describe a method of focal cooling of the head and its effects on hypoxic-ischemic cerebral damage in neonatal rat. Focal cooling of the head was obtained by positioning a catheter under the scalp ipsilateral to the ligated common carotid artery a
Publikováno v:
Biology of the neonate. 65(2)
The effect of unilateral perinatal cerebral hypoxic-ischemic damage on the gross development of the opposite hemisphere was investigated in immature rats. Eight-day-old rats underwent unilateral common carotid artery ligation followed by exposure to
Autor:
Javad Towfighi, Cathy Housman
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 49:284
Caudal regression syndrome includes malformations ranging from mild forms of sacral agenesis to severe limb anomalies referred to as sirenomelia. The latter, in addition to sacral anomalies, shows malformed single lower limb and agenesis of rectum an
Publikováno v:
Acta Neuropathologica. 77:612-620
Light microscopic and ultrastructural changes of substantia nigra were studied in paralyzed ventilated rats with status epilepticus induced by mercaptopropionic acid. Some rats were killed at the end of seizure activity and others were examined in va