Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Cathy E Bakker"'
Autor:
Maija Castrén, Katariina E Lampinen, Riitta Miettinen, Eija Koponen, Ilkka Sipola, Cathy E Bakker, Ben A Oostra, Eero Castrén
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 221-229 (2002)
Both fragile X mental retardation protein (FMRP) and brain-derived neurotrophic factor (BDNF) are implicated in the maturation of neurons and in the higher cognitive functions. We have investigated whether FMRP and BDNF are reciprocally regulated in
Externí odkaz:
https://doaj.org/article/464ffc8ecfda4074b8d09e61e0b47f70
Autor:
Simona D'Antoni, Cathy E. Bakker, Sebastiano A. Musumeci, Giuseppe Calabrese, Ben A. Oostra, Maria Vincenza Catania, David L. Nelson, Raffaele Ferri, Judith R. Brouwer, Maurizio Elia, Carmela M. Bonaccorso
Publikováno v:
Experimental Neurology, 203(1), 233-240. Academic Press
Experimental neurology 203 (2007): 233–240. doi:10.1016/j.expneurol.2006.08.007
info:cnr-pdr/source/autori:Musumeci SA, Calabrese G, Bonaccorso CM, D'Antoni S, Brouwer JR, Bakker CE, Elia M, Ferri R, Nelson DL, Oostra BA, Catania MV./titolo:Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes./doi:10.1016%2Fj.expneurol.2006.08.007/rivista:Experimental neurology/anno:2007/pagina_da:233/pagina_a:240/intervallo_pagine:233–240/volume:203
Experimental neurology 203 (2007): 233–240. doi:10.1016/j.expneurol.2006.08.007
info:cnr-pdr/source/autori:Musumeci SA, Calabrese G, Bonaccorso CM, D'Antoni S, Brouwer JR, Bakker CE, Elia M, Ferri R, Nelson DL, Oostra BA, Catania MV./titolo:Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes./doi:10.1016%2Fj.expneurol.2006.08.007/rivista:Experimental neurology/anno:2007/pagina_da:233/pagina_a:240/intervallo_pagine:233–240/volume:203
The Fmr1 knockout (KO) mouse is characterized by an increased audiogenic seizure (AGS) susceptibility and is considered a good animal model for epilepsy and seizures in the human fragile-X (FRAX) syndrome. Here, we tested the hypothesis that the rein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db790dee4b2fe99a322aa4f2e9eee5e
https://doi.org/10.1016/j.expneurol.2006.08.007
https://doi.org/10.1016/j.expneurol.2006.08.007
Autor:
W. de Graaf, Edwin Mientjes, M. Joosten, B.A. Milojkovic, M. Ito, David L. Nelson, E. De Schutter, Tom J. H. Ruigrok, Frans VanderWerf, Cathy E. Bakker, Ben A. Oostra, Reinoud Maex, Sho Kakizawa, K. Yamaguchi, T. Ikeda, K. Onodera, Sebastiaan K. E. Koekkoek, Rob Willemsen, C. I. De Zeeuw, Bjorn R. Dortland, Albertine Ellen Smit
Publikováno v:
Neuron, 47(3), 339-352. Cell Press
Neuron
Neuron
Summary Absence of functional FMRP causes Fragile X syndrome. Abnormalities in synaptic processes in the cerebral cortex and hippocampus contribute to cognitive deficits in Fragile X patients. So far, the potential roles of cerebellar deficits have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2873e5774fcafa90b1e3f5f9f9f98125
https://doi.org/10.1016/j.neuron.2005.07.005
https://doi.org/10.1016/j.neuron.2005.07.005
Autor:
Eero Castrén, Seppo Heinonen, Ben A. Oostra, Cathy E. Bakker, Kim P. Larsson, Virve Kärkkäinen, Maija L. Castrén, Karl E.O. Åkerman, Topi A. Tervonen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of Ame, 102(49), 17834-17839. National Academy of Sciences
Fragile X syndrome, a common form of inherited mental retardation, is caused by the absence of the fragile X mental retardation protein (FMRP) due to a mutation in the FMR1 gene. We investigated the differentiation of neural stem cells generated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e775809bb172e28b7d39bc9d2925b94b
https://hdl.handle.net/1765/68206
https://hdl.handle.net/1765/68206
Autor:
Ben A. Oostra, R.F. Kooy, Cathy E. Bakker, Rudi D'Hooge, Ilse Gantois, Ruben H. Willemsen, P.P. De Deyn, Edwin Reyniers
Publikováno v:
Current molecular medicine
Current Molecular Medicine, 1, 447-455. Bentham Science Publishers B.V.
Current Molecular Medicine, 1, 447-455. Bentham Science Publishers B.V.
A mouse model for the fragile X syndrome, the most common form of inherited mental retardation, was generated a number of years ago. It shows characteristics compatible with the clinical symptoms of human patients. These include pathological changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33303afabc2c5e52dea564c3cb59c27
https://doi.org/10.2174/1566524013363492
https://doi.org/10.2174/1566524013363492
Autor:
Carola Bontekoe, Laura L. Kirkpatrick, Joris J. M. Schonkeren, Leontine van Unen, Cathy E. Bakker, André T. Hoogeveen, Ben A. Oostra, David L. Nelson, Filippo Tamanini, Hans Galjaard
Publikováno v:
Human Molecular Genetics. 9:1487-1493
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP and the fragile X-related proteins 1 and 2 (FXR1P and FXR2P) form a gene family with functional similarities, such as RNA binding, polyribosomal asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5996ae7be944b611b5ad0c01552c0274
https://doi.org/10.1093/hmg/9.10.1487
https://doi.org/10.1093/hmg/9.10.1487
Autor:
Cathy E. Bakker, Yolanda De Diego Otero, Ben A. Oostra, Rob Willemsen, Lies-Anne Severijnen, Prawien Raghoe, André T. Hoogeveen
Publikováno v:
Gene Funct. Dis., 1, 28-37
The absence of the FMR1 (fragile X mental retardation gene 1) gene product, protein FMRP (fragile X mental retardation protein) is causing the fragile X syndrome. FMRP, together with two homologues, called FXR1P and FXR2P, belongs to a small family o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d765766c467c5f9c31547a70634aad69
https://doi.org/10.1002/1438-826x(200005)1:1<28::aid-gnfd28>3.0.co
https://doi.org/10.1002/1438-826x(200005)1:1<28::aid-gnfd28>3.0.co
Autor:
R.F. Kooy, B. B. A. De Vries, P. J. Willems, P.P. De Deyn, Ruben H. Willemsen, Filippo Tamanini, Ingeborg M. Nieuwenhuizen, R. d' Hooge, Edwin Reyniers, B.A. Oostra, A. T. Hoogeveen, Cathy E. Bakker
Publikováno v:
Neuroscience Research Communications. 26:265-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4a6c0e2bba25497a48c5bb58b052a8
https://doi.org/10.1002/1520-6769(200005/06)26:3<265::aid-nrc13>3.0.co
https://doi.org/10.1002/1520-6769(200005/06)26:3<265::aid-nrc13>3.0.co
Autor:
Yolanda De Diego Otero, Prawien Raghoe, Carola Bontekoe, Rob Willemsen, Cathy E. Bakker, Tanya Luteijn, Ben A. Oostra, André T. Hoogeveen
Publikováno v:
Experimental Cell Research, 258, 162-170. Elsevier Inc.
Fragile X syndrome is caused by the absence of expression of the FMR1 gene. Both FXR1 and FXR2 are autosomal gene homologues of FMR1. The products of the three genes are belonging to a family of RNA-binding proteins, called FMRP, FXR1P, and FXR2P, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85221f2ec2a1eec3eb428990d98ac03c
https://doi.org/10.1006/excr.2000.4932
https://doi.org/10.1006/excr.2000.4932
Autor:
Jan Sijbers, Annemie Van der Linden, Patrick Willems, Edwin Reyniers, Marleen Verhoye, Ben A. Oostra, R. Frank Kooy, Cathy E. Bakker
Publikováno v:
European Journal of Human Genetics, 7, 526-532. Nature Publishing Group
European journal of human genetics
European journal of human genetics
Magnetic resonance imaging (MRI) of the brain of fragile X patients, the most frequent form of inherited mental retardation, has revealed abnormalities in the size of specific brain structures, including the cerebellar vermis, the hippocampus, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae6717f620cd1e7f46f7708c9cf2c4b
https://doi.org/10.1038/sj.ejhg.5200348
https://doi.org/10.1038/sj.ejhg.5200348