Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Cathy Drexler"'
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Design, synthesis, structural analysis and atropoisomerisation studies of polynucleating ligands based on porphyrins bearing catechol unitsDedicated to H. B. Kagan on the occasion of his 71st birthday
Autor: Cathy Drexler, Bertrand Zimmer, Sabine Erhardt, Mir Wais Hosseini, André De Cian, Véronique Bulach
Publikováno v: New Journal of Chemistry. 26:43-57
New polynucleating ligands based on a combination of a meso-tetrakis(phenyl)porphyrin core and four catecholamido units connected at the ortho positions of the phenyl moieties have been prepared. All four atropoisomers of the methoxy-protected meso-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4574af2134cfe3d2beb7638160028b5
https://doi.org/10.1039/b104084g
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2
Pretreatment with Dexmedetomidine
Autor: William T. Schmeling, Cathy Drexler, Pragati Ganjoo, Michael Staunton, Neil E. Farber
Publikováno v: Anesthesia & Analgesia. 88:625-632
UNLABELLED: The sedative and anesthetic-sparing ability of the alpha2-adrenergic agonist dexmedetomidine is well documented. In this study, we identified the effects of halothane, with and without dexmedetomidine, on hemodynamic and electroencephalog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b75e4fb84c69da5bd5b697fc5054f51
https://doi.org/10.1213/00000539-199903000-00030
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3
Design and Synthesis of Porphyrins Bearing Catechols
Autor: Mir Wais Hosseini, Cathy Drexler, André De Cian, Jean Fischer
Publikováno v: Tetrahedron Letters. 38:2993-2996
The synthesis of meso-tetraarylporphyrines bearing 1–4 catechoylamid groups was achieved. Among the four new compounds prepared, the structure of the disubstituted ligand was elucidated in the solid state by an X-ray analysis. © 1997 Elsevier Scie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf7e2b7e00d95c886f68f109ae8c1d89
https://doi.org/10.1016/s0040-4039(97)00541-8
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5
ChemInform Abstract: Design, Synthesis and Cleaving Activity of an Abiotic Nuclease Based on a Manganese(III) Porphyrin Complex Bearing Two Acridine Moieties
Autor: Bernard Meunier, Cathy Drexler, Geneviève Pratviel, Mir Wais Hosseini
Publikováno v: ChemInform. 29
The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5ce63c559b08b58e0cc8d1fe926a662
https://doi.org/10.1002/chin.199845159
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6
Effects of hypoxia-reoxygenation on microvascular endothelial function in the rat hippocampal slice
Autor: William T. Schmeling, Michael G. Dulitz, Neil E. Farber, Cathy Drexler, Dale C. Ekbom, Michael Staunton
Publikováno v: Anesthesiology. 91(5)
Background Cerebral ischemia and hypoxia may cause injury to both neuronal and vascular tissue. The direct effects of hypoxia on endothelial function in intraparenchymal cerebral arterioles are unknown. Using a modification of the rat brain slice pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e8636ca4c9870c5e14ccc49b510287
https://pubmed.ncbi.nlm.nih.gov/10551599
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7
HTRF® KinEASETM: a new solution for screening serine-threonine kinases
Autor: Cathy Drexler
Publikováno v: Nature Methods. 3:I-II
The generation of drugs that modulate kinase activity has become a prime focus of the pharmaceutical industry. Cisbio, in partnership with Upstate, has made available the universal HTRF KinEASE assay for serine-threonine kinases (STKs). This article
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e6fa84d5f26b3a9bf0c77c5864a3877
https://doi.org/10.1038/nmeth883
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8
Design, synthesis and structural studies on polynucleating ligands based on atropoisomerism of catechol bearing porphyrins
Autor: Cathy Drexler, Mir Wais Hosseini, Jean-Marc Planeix, Gilles Stupka, André De Cian, Jean Fischer
Publikováno v: Chemical Communications. :689-690
High yield syntheses of all four atropoisomers of the meso-tetrakis(o-catecholamidophenyl)porphyrin has been achieved; all four atropoisomers were isolated and characterised by NMR spectroscopy; for the methyl protected 2αβαβ and 2α4 atropoisome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b697c2862b8aad45d5cb1440e7c80ae
https://doi.org/10.1039/a707949d
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9
Design, synthesis and cleaving activity of an abiotic nuclease based on a manganese(III) porphyrin complex bearing two acridine moieties
Autor: Cathy Drexler, Mir Wais Hosseini, Geneviève Pratviel, Bernard Meunier
Publikováno v: Chemical Communications. :1343-1344
The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f74babc38cc2594966d2a58825e75ee
https://doi.org/10.1039/a801095a
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