Výsledky vyhledávání - "Cathy C, Lester"

A New Approach Methodology (NAM) Based Assessment of Butylated hydroxytoluene (BHT) for Endocrine Disruption Potential

Autor: K Nadira, De Abrew, Ted, Natoli, Cathy C, Lester, Xiaohong, Wang, Mahmoud, Shobair, Arvind, Subramanian, George P, Daston

Publikováno v: Toxicological Sciences. 190:227-241

Butylated hydroxytoluene (BHT) is a synthetic antioxidant widely used in many industrial sectors. BHT is a well-studied compound for which there are many favorable regulatory decisions. However, a recent opinion by the French Agency for Food, Environ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8be4e94e90eb26145c329a9cd52585
https://doi.org/10.1093/toxsci/kfac099

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Retention of the Cis Proline Conformation in Tripeptide Fragments of Bovine Pancreatic Ribonuclease A Containing a Non-natural Proline Analogue, 5,5-Dimethylproline

Autor: Jin-Lin Peng, Ervin Welker, David M. Rothwarf, Yue-Jin Li, Harold A. Scheraga, Lianshan Zhang, and James P. Tam, Theodore W. Thannhauser, Seong Soo A. An, Cathy C. Lester

Publikováno v: Journal of the American Chemical Society. 121:11558-11566

Attention is focused on l-5,5-dimethylproline (dmP) as a substitute to lock l-proline (Pro) in a cis conformation in peptides and proteins, to prevent cis/trans isomerization when a protein with cis X-Pro peptide groups unfolds. Procedures have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30a004a1f4d8f76d0705b6712d8d83f9
https://doi.org/10.1021/ja9930317

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Elicited cell suspension cultures of apple (Malus×domestica) cv. Liberty produce biphenyl phytoalexins

Autor: Wlodzimierz Borejsza-Wysocki, Cathy C. Lester, Geza Hrazdina, Athula B. Attygalle

Publikováno v: Phytochemistry. 50:231-235

Yeast extract treated cell suspension cultures from a scab (Venturia inaequalis) resistant apple cultivar, Malus×domestica cv. Liberty produce dibenzofuran and biphenyl compounds as part of their defense system against fungal invasion. We have isola

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c34ae64f9e5b237d88063257d425df6
https://doi.org/10.1016/s0031-9422(98)00509-3

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New general approach for determining the solution structure of a ligand bound weakly to a receptor: structure of a fibrinogen A?-like peptide bound to thrombin(S195A) obtained using NOE distance constraints and an ECEPP/3 flexible docking program

Autor: Elsie E. DiBella, Harold A. Scheraga, Muriel C. Maurer, Jean-Yves Trosset, Cathy C. Lester

Publikováno v: Proteins: Structure, Function, and Genetics. 34:29-48

A new approach incorporating flexible docking simulations and NMR data is presented for calculating the bound conformation of a ligand that interacts weakly with an enzyme. This approach consists of sampling directly the conformation of a flexible li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32251745bb3d46a79d4402da2f79b475
https://doi.org/10.1002/(sici)1097-0134(19990101)34:1<29::aid-prot4>3.0.co

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A Caffeoylcyclohexane-1-Carboxylic Acid Derivative From Asimina Triloba

Autor: Paul Feeny, Cathy C. Lester, Meena Haribal

Publikováno v: Phytochemistry. 49:103-108

Three caffeoyl derivatives of 1,3,4,5-tetrahydroxycyclohexane 1-carboxylic acid, one of them an oviposition stimulant for the zebra swallowtail butterfly, Eurytides marcellus , were isolated from Asimina triloba . The structure of the active isomer,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d7d6006baec6a988090ebd89478ba66
https://doi.org/10.1016/s0031-9422(97)00804-2

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Structural Characterization of an Analog of the Major Rate-Determining Disulfide Folding Intermediate of Bovine Pancreatic Ribonuclease A

Autor: Cathy C. Lester, Diane E. Zimmerman, Sakurako Shimotakahara, Harold A. Scheraga, Gaetano T. Montelione, John H. Laity

Publikováno v: Biochemistry. 36:12683-12699

The major rate-determining step in the oxidative regeneration of bovine pancreatic ribonuclease A (RNase A) proceeds through des-[40-95] RNase A, a three-disulfide intermediate lacking the Cys40-Cys95 disulfide bond. An analog of this intermediate, [

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e9dc6cf93e0a4d456a2c46847ff132
https://doi.org/10.1021/bi970878b

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Structure-function studies of mEGF: Probing the type Iβ-turn between residues 25 and 26

Autor: Cathy C. Lester, Baiyang Wang, Ray Wu, Harold A. Scheraga

Publikováno v: Journal of Protein Chemistry. 14:753-762

The interaction between epidermal growth factor (EGF) and its receptor molecule is not completely understood and has received much attention recently. Studies combining site-directed mutagenesis and NMR spectroscopy have identified a number of EGF re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c3eeebb1870b00b0d07e294b3717be
https://doi.org/10.1007/bf01886915

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Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics

Autor: Cathy C. Lester, David G. Sanford, Suzanne F. O'Handley, Suse Broyde, Brian E. Hingerty, Rong Xu, Thomas R. Krugh

Publikováno v: Biochemistry. 32(10)

An N-acetyl-2-aminofluorene (AAF) modified deoxyoligonucleotide duplex, d(C1-C2-A3-C4-[AAF-G5]-C6-A7-C8-C9).d(G10-G11-T12-G13-C14-++ +G15-T16-G17-G18), was studied by one- and two-dimensional NMR spectroscopy. Eight of the nine complementary nucleoti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32014256ff88705ce3dbe64d19169a5f
https://pubmed.ncbi.nlm.nih.gov/8448107

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