Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Cathy A. Cogswell"'
Autor:
John B. Lees-Shepard, Masakazu Yamamoto, Arpita A. Biswas, Sean J. Stoessel, Sarah-Anne E. Nicholas, Cathy A. Cogswell, Parvathi M. Devarakonda, Michael J. Schneider, Samantha M. Cummins, Nicholas P. Legendre, Shoko Yamamoto, Vesa Kaartinen, Jeffrey W. Hunter, David J. Goldhamer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Fibrodysplasia ossificans progressiva is a severe disorder characterized by heterotopic ossification, and is caused by mutations in ACVR1. Here, the authors show that expression of mutant ACVR1 in fibro/adipogenic progenitors recapitulates disease pr
Externí odkaz:
https://doaj.org/article/cce620ded4304ad1a71c991a24918aac
Autor:
Jeffrey W. Hunter, Nicholas P. Legendre, David J. Goldhamer, Sarah Anne E. Nicholas, Masakazu Yamamoto, Michael J Schneider, Arpita A. Biswas, Samantha M. Cummins, Sean J. Stoessel, John B Lees-Shepard, Shoko Yamamoto, Cathy A. Cogswell, Vesa Kaartinen, Parvathi M. Devarakonda
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disorder characterized by progressive and profoundly disabling heterotopic ossification (HO). Here we show that fibro/adipogenic progenitors (FAPs) are a major cell-of-origin of