Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cathryn L Ugalde"'
Autor:
Cathryn L. Ugalde, Sarah J. Annesley, Shane E. Gordon, Katelyn Mroczek, Matthew A. Perugini, Victoria A. Lawson, Paul R. Fisher, David I. Finkelstein, Andrew F. Hill
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 1 (2020)
The misfolding and aggregation of the largely disordered protein, α-synuclein, is a central pathogenic event that occurs in the synucleinopathies, a group of neurodegenerative disorders that includes Parkinson's disease. While there is a clear link
Externí odkaz:
https://doaj.org/article/39a36e9f07b34b0bbb7733b0f43b91cb
Autor:
David Finkelstein, Andrew F. Hill, Shane E. Gordon, Amirmohammad Nasiri Kenari, Cathryn L Ugalde, Mitch Shambrook, Victoria A. Lawson, Bradley M. Coleman, Matthew A. Perugini
Publikováno v:
Journal of Extracellular Vesicles
The misfolding and fibrillization of the protein, α‐synuclein (αsyn), is associated with neurodegenerative disorders referred to as the synucleinopathies. Understanding the mechanisms of αsyn misfolding is an important area of interest given tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bb7b8e27354038ac37dd2f761f8848
http://europepmc.org/articles/PMC7726797
http://europepmc.org/articles/PMC7726797
Markers of A1 astrocytes stratify to molecular sub-types in sporadic Creutzfeldt–Jakob disease brain
Autor:
Andrew F. Hill, Victoria A. Lawson, Catriona McLean, Christiane Stehmann, Victoria Lewis, Cathryn L Ugalde, Steven J. Collins
Publikováno v:
Brain Communications
Astrocytes are glial cells of the central nervous system that become reactive under conditions of stress. The functional properties of reactive astrocytes depend on their stimulus that induces the upregulation of specific genes. Reactive astrocytes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7df2e8b8d9ee297d15a0466e1099ad
http://europepmc.org/articles/PMC7425384
http://europepmc.org/articles/PMC7425384
Autor:
Victoria A. Lawson, David Finkelstein, Paul R. Fisher, Sarah J. Annesley, Katelyn Mroczek, Shane E. Gordon, Cathryn L Ugalde, Matthew A. Perugini, Andrew F. Hill
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 13, Iss 1 (2020)
Disease Models & Mechanisms, Vol 13, Iss 1 (2020)
The misfolding and aggregation of the largely disordered protein, α-synuclein, is a central pathogenic event that occurs in the synucleinopathies, a group of neurodegenerative disorders that includes Parkinson's disease. While there is a clear link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bee260ef07e3113ccf536aaa643e012
https://pubmed.ncbi.nlm.nih.gov/31848207
https://pubmed.ncbi.nlm.nih.gov/31848207
The misfolding and aggregation of α-synuclein (αsyn) in the central nervous system is associated with a group of neurodegenerative disorders referred to as the synucleinopathies. In addition to being a pathological hallmark of disease, it is now we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c507a5bad9f36895709ea2c01cb496
https://europepmc.org/articles/PMC6556586/
https://europepmc.org/articles/PMC6556586/
Publikováno v:
Journal of Neurochemistry. 139:162-180
Proteinopathies represent a group of diseases characterized by the unregulated misfolding and aggregation of proteins. Accumulation of misfolded protein in the central nervous system (CNS) is associated with neurodegenerative diseases, such as the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185012c98a7cd8bef7af0715b3a8bcad
https://doi.org/10.1111/jnc.13772
https://doi.org/10.1111/jnc.13772
Autor:
John D. Wade, Elaheh Jamasbi, Roy M. Robins-Browne, Cathryn L Ugalde, Julien Tailhades, Robyn A. Sharples, Nitin A. Patil, Frances Separovic, Giuseppe D. Ciccotosto, Mohammed Akhter Hossain
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848:2031-2039
The mechanism of membrane disruption by melittin (MLT) of giant unilamellar vesicles (GUVs) and live cells was studied using fluorescence microscopy and two fluorescent synthetic analogues of MLT. The N-terminus of one of these was acylated with thio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eda7c2a029feda276a8b462838a775
https://doi.org/10.1016/j.bbamem.2015.06.004
https://doi.org/10.1016/j.bbamem.2015.06.004
Autor:
Emmanuel Koumoundouros, Cathryn L Ugalde, Louise M. Harkness, Donna Barker, Garry Barcham, Heidi Bao, Janette K. Burgess, Joanne Van der Velden, Kenneth J. Snibson, Louise Organ, Ana Tokanovic
Publikováno v:
Scientific Reports
Scientific Reports, 6:26309. Nature Publishing Group
Scientific Reports, 6:26309. Nature Publishing Group
Tumstatin, a protein fragment of the alpha-3 chain of Collagen IV, is known to be significantly reduced in the airways of asthmatics. Further, there is evidence that suggests a link between the relatively low level of tumstatin and the induction of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f275f3841fb61c0ce4dfb817981625
https://doi.org/10.1038/srep26309
https://doi.org/10.1038/srep26309