Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Cathryn L Haigh"'
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0312837 (2024)
Prion diseases are transmissible, fatal neurologic diseases of mammals caused by the accumulation of mis-folded, disease associated prion protein (PrPd). Creutzfeldt-Jakob Disease (CJD) is the most common human prion disease and can occur by sporadic
Externí odkaz:
https://doaj.org/article/e2df01fa527a4089ab53111ab9bc9ed3
Autor:
Simote T Foliaki, Cathryn L Haigh
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011714 (2023)
Externí odkaz:
https://doaj.org/article/a77faf94c2064028b71f3f9455176587
Autor:
Sarah Vascellari, Christina D Orrù, Bradley R Groveman, Sabiha Parveen, Giuseppe Fenu, Giada Pisano, Giuseppe Piga, Giulia Serra, Valentina Oppo, Daniela Murgia, Andrea Perra, Fabrizio Angius, Andrew G Hughson, Cathryn L Haigh, Aldo Manzin, Giovanni Cossu, Byron Caughey
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011456 (2023)
Abnormal deposition of α-synuclein is a key feature and biomarker of Parkinson's disease. α-Synuclein aggregates can propagate themselves by a prion-like seeding-based mechanism within and between tissues and are hypothesized to move between the in
Externí odkaz:
https://doaj.org/article/f1359ada37b94233a8723855297fbd28
Autor:
Simote T Foliaki, Anna Smith, Benjamin Schwarz, Eric Bohrnsen, Catharine M Bosio, Katie Williams, Christina D Orrú, Hailey Lachenauer, Bradley R Groveman, Cathryn L Haigh
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010565 (2023)
Fatal familial insomnia (FFI) is a rare neurodegenerative disease caused by a dominantly inherited single amino acid substitution (D178N) within the prion protein (PrP). No in vitro human brain tissue model for this disease has previously been availa
Externí odkaz:
https://doaj.org/article/5f44df8f953e4e0d8120b3a7928318d2
Autor:
Anna Smith, Bradley R Groveman, Clayton Winkler, Katie Williams, Ryan Walters, Jue Yuan, Wenquan Zou, Karin Peterson, Simote T Foliaki, Cathryn L Haigh
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0277051 (2022)
Prion diseases are a group of rare, transmissible, and invariably fatal neurodegenerative diseases that affect both humans and animals. The cause of these diseases is misfolding of the prion protein into pathological isoforms called prions. Of all hu
Externí odkaz:
https://doaj.org/article/920ac69e16944f7f8f246830c303222a
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009747 (2021)
Externí odkaz:
https://doaj.org/article/7a9007754e69457bafde80810fc26b4f
Autor:
Simote T Foliaki, Brent Race, Katie Williams, Chase Baune, Bradley R Groveman, Cathryn L Haigh
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259597 (2021)
Prion diseases are progressive, neurodegenerative diseases affecting humans and animals. Also known as the transmissible spongiform encephalopathies, for the hallmark spongiform change seen in the brain, these diseases manifest increased oxidative da
Externí odkaz:
https://doaj.org/article/23606fe40de04f528270e8cb9d2e7f10
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 6, Pp 1019-1020 (2020)
Externí odkaz:
https://doaj.org/article/9d0ab35d2375425bb03b132d8f7949d1
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134680 (2015)
Internal cleavage of the cellular prion protein generates two well characterised N-terminal fragments, N1 and N2. These fragments have been shown to bind to anionic phospholipids at low pH. We sought to investigate binding with other lipid moieties a
Externí odkaz:
https://doaj.org/article/a7de4e258aaa4f329cb54e11c5ed9461
Autor:
Cathryn L Haigh, Steven J Collins
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Externí odkaz:
https://doaj.org/article/d4856b1724fb44bcb939ba70f5751b85