Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cathryn, Mellersh"'
Autor:
Rodrigo Gutierrez‐Quintana, Cathryn Mellersh, Annette Wessmann, Maria Ortega, Jacques Penderis, Samuel Sharpe, Eleanor Freeman, Lynn Stevenson, Louise Burmeister
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 5, Pp 2306-2314 (2021)
Abstract Background Hereditary sensory and autonomic neuropathies (HSANs) are a group of genetic disorders affecting the peripheral nervous system. Two different associated variants have been identified in dogs: 1 in Border Collies and 1 in Spaniels
Externí odkaz:
https://doaj.org/article/3e04c9c0772e409182f18cc7d36190c6
Autor:
Hannah Joyce, Louise M Burmeister, Hattie Wright, Lorraine Fleming, James A C Oliver, Cathryn Mellersh
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0272477 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0251071.].
Externí odkaz:
https://doaj.org/article/5c589500c4d043e7ba8bda1fd7a74c12
Autor:
Hannah Joyce, Louise M Burmeister, Hattie Wright, Lorraine Fleming, James A C Oliver, Cathryn Mellersh
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251071 (2021)
PurposeThree related male English Cocker Spaniels (ECS) were reported to be congenitally blind. Examination of one of these revealed complete retinal detachment. A presumptive diagnosis of retinal dysplasia (RD) was provided and pedigree analysis was
Externí odkaz:
https://doaj.org/article/68f0e84fb78246afb814979f7bbeaf34
Autor:
Jessica J Hayward, Maria Kelly-Smith, Adam R Boyko, Louise Burmeister, Luisa De Risio, Cathryn Mellersh, Julia Freeman, George M Strain
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232900 (2020)
Congenital deafness in the domestic dog is usually related to the presence of white pigmentation, which is controlled primarily by the piebald locus on chromosome 20 and also by merle on chromosome 10. Pigment-associated deafness is also seen in othe
Externí odkaz:
https://doaj.org/article/7005f561ac744709ac3f851b88909f60
Publikováno v:
Canine Genetics and Epidemiology, Vol 5, Iss 1, Pp 1-4 (2018)
Externí odkaz:
https://doaj.org/article/07420f85e0da41b2aebafcb168cbe379
Autor:
Robert Lowe, Carl Barton, Christopher A. Jenkins, Christina Ernst, Oliver Forman, Denise S. Fernandez-Twinn, Christoph Bock, Stephen J. Rossiter, Chris G. Faulkes, Susan E. Ozanne, Lutz Walter, Duncan T. Odom, Cathryn Mellersh, Vardhman K. Rakyan
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Mammalian species exhibit a wide range of lifespans. To date, a robust and dynamic molecular readout of these lifespan differences has not yet been identified. Recent studies have established the existence of ageing-associated dif
Externí odkaz:
https://doaj.org/article/fcef5f9e8b4f4874903093389bdbf7dd
Autor:
Linda Anderegg, Michelle Im Hof Gut, Udo Hetzel, Elizabeth W Howerth, Fabienne Leuthard, Kaisa Kyöstilä, Hannes Lohi, Louise Pettitt, Cathryn Mellersh, Katie M Minor, James R Mickelson, Kevin Batcher, Danika Bannasch, Vidhya Jagannathan, Tosso Leeb
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008378 (2019)
Primary ciliary dyskinesia (PCD) is a hereditary defect of motile cilia in humans and several domestic animal species. Typical clinical findings are chronic recurrent infections of the respiratory tract and fertility problems. We analyzed an Alaskan
Externí odkaz:
https://doaj.org/article/c8cc33b168bf4cbdaf4cb039cfd7bb57
Autor:
Suvi Mäkeläinen, Marta Gòdia, Minas Hellsand, Agnese Viluma, Daniela Hahn, Karim Makdoumi, Caroline J Zeiss, Cathryn Mellersh, Sally L Ricketts, Kristina Narfström, Finn Hallböök, Björn Ekesten, Göran Andersson, Tomas F Bergström
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1007873 (2019)
Autosomal recessive retinal degenerative diseases cause visual impairment and blindness in both humans and dogs. Currently, no standard treatment is available, but pioneering gene therapy-based canine models have been instrumental for clinical trials
Externí odkaz:
https://doaj.org/article/440e2dd2ef7541c0a70a7c12f3d6f9ec
An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed
Autor:
Oliver P. Forman, Rebekkah J. Hitti, Louise Pettitt, Christopher A. Jenkins, Dennis P. O’Brien, G. Diane Shelton, Luisa De Risio, Rodrigo Gutierrez Quintana, Elsa Beltran, Cathryn Mellersh
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 9, Pp 2687-2692 (2016)
Sensory neuropathy in the Border Collie is a severe neurological disorder caused by the degeneration of sensory and, to a lesser extent, motor nerve cells with clinical signs starting between 2 and 7 months of age. Using a genome-wide association stu
Externí odkaz:
https://doaj.org/article/aaea78f34fbf4f38862b5ce063701ed8
Autor:
Anina Bauer, Vidhya Jagannathan, Sandra Högler, Barbara Richter, Neil A McEwan, Anne Thomas, Edouard Cadieu, Catherine André, Marjo K Hytönen, Hannes Lohi, Monika M Welle, Petra Roosje, Cathryn Mellersh, Margret L Casal, Tosso Leeb
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007264 (2018)
Lethal acrodermatitis (LAD) is a genodermatosis with monogenic autosomal recessive inheritance in Bull Terriers and Miniature Bull Terriers. The LAD phenotype is characterized by poor growth, immune deficiency, and skin lesions, especially at the paw
Externí odkaz:
https://doaj.org/article/00d133befa1a4234a8f5487df49c7e40