α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK.

Autor: Cathrine Laustrup Møller, Rasmus Kjøbsted, Pablo J Enriori, Thomas Elbenhardt Jensen, Cecilia Garcia-Rudaz, Sara A Litwak, Kirsten Raun, Jørgen Wojtaszewski, Birgitte Schjellerup Wulff, Michael A Cowley

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0157027 (2016)

The melanocortin system includes five G-protein coupled receptors (family A) defined as MC1R-MC5R, which are stimulated by endogenous agonists derived from proopiomelanocortin (POMC). The melanocortin system has been intensely studied for its central

Externí odkaz: https://doaj.org/article/f799973a868e4c48b6024e5534b64b92

Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes

Autor: Troels Mygind Jensen, Peter M. Nilsson, Türküler Özgümüs, Marja-Riitta Taskinen, Carol Forsblom, Thomas Nyström, Kerstin Brismar, Gun Jörneskog, Jani K. Haukka, Tore Julsrud Berg, Mats Eliasson, Peter Rossing, Henrik Falhammar, Ruchi Jain, Leon Eyrich Jessen, Sergiu-Bogdan Catrina, Peter Spégel, Björn Eliasson, Cathrine Laustrup Møller, Mahmoud Al-Majdoub, Valeriya Lyssenko, Ele Ferrannini, Elsa du Plessis, Per-Henrik Groop, Leif Groop, Magdalena Keindl

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Jain, R, Özgümüş, T, Jensen, T M, du Plessis, E, Keindl, M, Møller, C L, Falhammar, H, Nyström, T, Catrina, S B, Jörneskog, G, Jessen, L E, Forsblom, C, Haukka, J K, Groop, P H, Rossing, P, Groop, L, Eliasson, M, Eliasson, B, Brismar, K, Al-Majdoub, M, Nilsson, P M, Taskinen, M R, Ferrannini, E, Spégel, P, Berg, T J & Lyssenko, V 2020, ' Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes ', Scientific Reports, vol. 10, no. 1, 11561 . https://doi.org/10.1038/s41598-020-68130-y
Scientific Reports

Identification of biomarkers associated with protection from developing diabetic complications is a prerequisite for an effective prevention and treatment. The aim of the present study was to identify clinical and plasma metabolite markers associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0593c96833d9f467c0b7a8346aafede
http://hdl.handle.net/10852/79862

The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo

Autor: Frank Reimann, Roger D. Cone, Helen M. Cox, Cathrine Laustrup Møller, Gregory J. Digby, Jens J. Holst, Birgitte Holst, Brandon L. Panaro, Thue W. Schwartz, Iain R. Tough, Robert T. Matthews, Fiona M. Gribble, Maja S. Engelstoft, Berit Svendsen

Publikováno v: Cell Metabolism. 20(6):1018-1029

SummaryThe melanocortin-4 receptor (MC4R) is expressed in the brainstem and vagal afferent nerves and regulates a number of aspects of gastrointestinal function. Here we show that the receptor is also diffusely expressed in cells of the gastrointesti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce8402a657aa3f105352f3610862e69

Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study

Autor: Signe S. Torekov, Daniel R. Witte, Dorte Vistisen, Marit E. Jørgensen, Kristine Færch, Cathrine Laustrup Møller, Torsten Lauritzen, Torben Hansen, Jens J. Holst, Anna Jonsson, Oluf Pedersen, Nanna B. Johansen

Publikováno v: Møller, C L, Vistisen, D, Færch, K, Johansen, N B, Witte, D R, Jonsson, A, Pedersen, O, Hansen, T, Lauritzen, T, Jørgensen, M E, Torekov, S S & Holst, J J 2016, ' Glucose-dependent insulinotropic polypeptide is associated with lower low-density lipoprotein but unhealthy fat distribution, independent of insulin : The addition-pro study ', Journal of Clinical Endocrinology and Metabolism, vol. 101, no. 2, pp. 485-493 . https://doi.org/10.1210/jc.2015-3133

Context: Glucose-dependent insulinotropic polypeptide (GIP) may increase lipid clearance by stimulating lipid uptake. However, given that GIP promotes release of insulin by the pancreas and insulin is anti-lipolytic, the effect may be indirect. Objec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae01a521d7893c3a02ae53800d42f22
https://pubmed.ncbi.nlm.nih.gov/26505824

Sucrose vs artificial sweeteners: differences in 24 hour substrate oxidation rates, but not in energy expenditure after 10 weeks ad libitum intake in overweight subjects

Autor: Anne Raben, Bente Kramer Møller, Vasilaras, T. H., Anne Cathrine Laustrup Møller, Anne Flint, Arne Astrup

Publikováno v: University of Copenhagen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d05b4f25f2c0a362fdb8cb8e4360f1b
https://curis.ku.dk/portal/en/publications/sucrose-vs-artificial-sweeteners-differences-in-24-hour-substrate-oxidation-rates-but-not-in-energy-expenditure-after-10-weeks-ad-libitum-intake-in-overweight-subjects(b0a89794-9a68-4997-b7e0-2279eef86b58).html