Výsledky vyhledávání - "Cathrine E. Costello"

Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis

Autor: David R. Pimental, Yuhan Ji, Richard A. Cohen, Mark E. McComb, Cathrine E. Costello, Rebecca Zee, Markus Bachschmid, Vikas Kumar, Joseph R. Burgoyne, Dagmar J. Haeussler, Cheng Lin

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(2)

Here we demonstrate a new paradigm in redox signaling, whereby oxidants resulting from metabolic stress directly alter protein palmitoylation by oxidizing reactive cysteine thiolates. In mice fed a high-fat, high-sucrose diet and in cultured endothel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7190de28775b6fd508418f74a31d9b6
https://pubmed.ncbi.nlm.nih.gov/22085642

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