Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Cathrine Broberg Vågbø"'
Autor:
Sigrid Ravn Berg, Aida Dikic, Animesh Sharma, Lars Hagen, Cathrine Broberg Vågbø, Alexey Zatula, Kristine Misund, Anders Waage, Geir Slupphaug
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Despite significant advancements in treatment strategies, multiple myeloma remains incurable. Additionally, there is a distinct lack of reliable biomarkers that can guide initial treatment decisions and help determine suitable rep
Externí odkaz:
https://doaj.org/article/fa84fcbbd8e04435a653c7fe49caed80
Autor:
Michaela Dohnalkova, Kyrylo Krasnykov, Mateusz Mendel, Lingyun Li, Olesya Panasenko, Fabienne Fleury-Olela, Cathrine Broberg Vågbø, David Homolka, Ramesh S. Pillai
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112786- (2023)
Summary: Eukaryotic RNA pol II transcripts are capped at the 5′ end by the methylated guanosine (m7G) moiety. In higher eukaryotes, CMTR1 and CMTR2 catalyze cap-proximal ribose methylations on the first (cap1) and second (cap2) nucleotides, respect
Externí odkaz:
https://doaj.org/article/b5fb7d507b834a0db489304cbd36a63c
Autor:
Per Arne Aas, Renana Rabe, Vuk Palibrk, Geir Slupphaug, Kristian Lied Wollen, Lars Hagen, Davi de Miranda Fonseca, Hilde O. Erlandsen, Animesh Sharma, Cathrine Broberg Vågbø, Tobias S. Iveland, Magnar Bjørås, Bjørnar Sporsheim, Nima Mosammaparast
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-22 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-22 (2021)
Background Reversible enzymatic methylation of mammalian mRNA is widespread and serves crucial regulatory functions, but little is known to what degree chemical alkylators mediate overlapping modifications and whether cells distinguish aberrant from
Autor:
Thiago Wendt Viola, Ziqi Wang, Cathrine Broberg Vågbø, Christophe Magnan, Xiang Li, Sachithrani U. Madugalle, Jiayu Yin, Magnar Bjørås, Robert C. Spitale, Wei Wei, Esmi L. Zajaczkowski, Pierre Baldi, Qiongyi Zhao, Luis Eduardo Wearick-Silva, Rodrigo Grassi-Oliveira, Ke Ke, Laura J. Leighton, Timothy W. Bredy, Quan Lin, Paul R. Marshall, Sarah Nainar, Michael R. Emami
Publikováno v:
Nature neuroscience
DNA modification is known to regulate experience-dependent gene expression. However, beyond cytosine methylation and its oxidated derivatives, very little is known about the functional importance of chemical modifications on other nucleobases in the
A large number of RNA modifications are known to affect processing and function of rRNA, tRNA and mRNA 1. The N4-acetylcytidine (ac4C) is the only known RNA acetylation event and is known to occur on rRNA, tRNA and mRNA 2,3. RNA modification by acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a799640f145a60927a169a1be31d7be8
https://doi.org/10.1101/2021.04.06.438707
https://doi.org/10.1101/2021.04.06.438707
Autor:
Kamila Delaney, Radha Raman Pandey, Florian A. Steiner, David Homolka, Ramesh S. Pillai, K.M. Chen, Mateusz Mendel, Cathrine Broberg Vågbø, Joanna M. Wenda
Publikováno v:
3125-3142.e25
Cell
Cell
Summary The N6-methyladenosine (m6A) RNA modification is used widely to alter the fate of mRNAs. Here we demonstrate that the C. elegans writer METT-10 (the ortholog of mouse METTL16) deposits an m6A mark on the 3′ splice site (AG) of the S-adenosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47b350471edf502b4abe27a847ae2cc
https://hdl.handle.net/11250/2982829
https://hdl.handle.net/11250/2982829
Autor:
Eliane Grundbacher, Primo Schär, Alexandra M. Hrovat, Anna Kuśnierczyk, Cathrine Broberg Vågbø, David Schuermann, Simon D. Schwarz, Jianming Xu
Publikováno v:
F1000Research
Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors di
Autor:
B. Paizs, Edgar Hartsuiker, D. Chaplin, S. Gollins, L. Boeckemeier, Cathrine Broberg Vågbø, R. Beardmore, M. U. Gasasira, R. Kraehenbuehl, S. A. E. Lambert, Ellen G Vernon, A. Keszthelyi, Hans E. Krokan
Publikováno v:
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (22), pp.eaaz4126. ⟨10.1126/sciadv.aaz4126⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (22), pp.eaaz4126. ⟨10.1126/sciadv.aaz4126⟩
Mre11 exonuclease activity removes gemcitabine from the nascent strand during DNA replication.
The Mre11 nuclease is involved in early responses to DNA damage, often mediated by its role in DNA end processing. MRE11 mutations and aberrant expres
The Mre11 nuclease is involved in early responses to DNA damage, often mediated by its role in DNA end processing. MRE11 mutations and aberrant expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b38365e0b9886b2161bbf5a4a44ede
https://hal.archives-ouvertes.fr/hal-03008931/document
https://hal.archives-ouvertes.fr/hal-03008931/document
Autor:
Radha Raman, Pandey, Elena, Delfino, David, Homolka, Adriana, Roithova, Kuan-Ming, Chen, Lingyun, Li, Giulia, Franco, Cathrine Broberg, Vågbø, Emmanuel, Taillebourg, Marie-Odile, Fauvarque, Ramesh S, Pillai
Publikováno v:
Cell reports. 32(7)
The 5' end of eukaryotic mRNAs is protected by the m
Autor:
Geir Slupphaug, Cathrine Broberg Vågbø
Publikováno v:
DNA Repair
Our genome is constantly subject to damage from exogenous and endogenous sources, and cells respond to such damage by initiating a DNA damage response (DDR). Failure to induce an adequate DDR can result in increased mutation load, chromosomal aberrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0028427ceca8a4401a8b3d38b5a4324e
https://hdl.handle.net/11250/2740057
https://hdl.handle.net/11250/2740057