Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cathrine B Vågbø"'
Autor:
Daria Zdżalik, Cathrine B Vågbø, Finn Kirpekar, Erna Davydova, Alicja Puścian, Agnieszka M Maciejewska, Hans E Krokan, Arne Klungland, Barbara Tudek, Erwin van den Born, Pål Ø Falnes
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98729 (2014)
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases.
Externí odkaz:
https://doaj.org/article/b2fee403fcd749dabb5b49aae995b66c
Autor:
Simon D. Schwarz, Jianming Xu, Kapila Gunasekera, David Schürmann, Cathrine B. Vågbø, Elena Ferrari, Geir Slupphaug, Michael O. Hottiger, Primo Schär, Roland Steinacher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The intracellular ATP-ribosyltransferases PARP1 and PARP2, contribute to DNA base excision repair (BER) and DNA demethylation and have been implicated in epigenetic programming in early mammalian development. Recently, proteomic analyses ide
Externí odkaz:
https://doaj.org/article/b655bc28a78b442da9f9980d84093de3
Autor:
Kristian Lied Wollen, Lars Hagen, Cathrine B. Vågbø, Renana Rabe, Tobias S. Iveland, Per Arne Aas, Animesh Sharma, Bjørnar Sporsheim, Hilde O. Erlandsen, Vuk Palibrk, Magnar Bjørås, Davi M. Fonseca, Nima Mosammaparast, Geir Slupphaug
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Reversible enzymatic methylation of mammalian mRNA is widespread and serves crucial regulatory functions, but little is known to what degree chemical alkylators mediate overlapping modifications and whether cells distinguish aberr
Externí odkaz:
https://doaj.org/article/5aba95e32975406eb6455786f238b3a7
Autor:
Alain R. Weber, Claudia Krawczyk, Adam B. Robertson, Anna Kuśnierczyk, Cathrine B. Vågbø, David Schuermann, Arne Klungland, Primo Schär
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Cytosine methylation is a dynamic DNA modification with the involvement of the base excision repair pathway suspected to be involved in demethylation. Here the authors show that TET1 and TDG interact to target modified bases and coordinate BER to avo
Externí odkaz:
https://doaj.org/article/44eb7c1d95384a8bb025afc098bf1cf5
Autor:
Monica D. Bjørge, Gunn A. Hildrestrand, Katja Scheffler, Rajikala Suganthan, Veslemøy Rolseth, Anna Kuśnierczyk, Alexander D. Rowe, Cathrine B. Vågbø, Susanne Vetlesen, Lars Eide, Geir Slupphaug, Yusaku Nakabeppu, Timothy W. Bredy, Arne Klungland, Magnar Bjørås
Publikováno v:
Cell Reports, Vol 13, Iss 12, Pp 2671-2678 (2015)
Ogg1 and Mutyh DNA glycosylases cooperate to prevent mutations caused by 8-oxoG, a major premutagenic DNA lesion associated with cognitive decline. We have examined behavior and cognitive function in mice deficient of these glycosylases. Ogg1−/−M
Externí odkaz:
https://doaj.org/article/4ac21c419fc4404d848fbcaac9fd6541
Autor:
Simon D. Schwarz, Eliane Grundbacher, Alexandra M. Hrovat, Jianming Xu, Anna Kuśnierczyk, Cathrine B. Vågbø, Primo Schär, David Schuermann
Publikováno v:
F1000Research, Vol 9 (2020)
Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors di
Autor:
Simon D. Schwarz, Eliane Grundbacher, Alexandra M. Hrovat, Jianming Xu, Anna Kuśnierczyk, Cathrine B. Vågbø, Primo Schär, David Schuermann
Publikováno v:
F1000Research, Vol 9 (2020)
Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors di