Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cathrin Klingeberg"'
Autor:
Stefanie Kreutmair, Lena Johanna Lippert, Cathrin Klingeberg, Corinna Albers-Leischner, Salome Yacob, Valeria Shlyakhto, Tony Mueller, Alina Mueller-Rudorf, Chuanjiang Yu, Sivahari Prasad Gorantla, Cornelius Miething, Justus Duyster, Anna Lena Illert
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The NPM-ALK fusion kinase is expressed in 60% of systemic anaplastic large-cell lymphomas (ALCL). A Nuclear Interaction Partner of ALK (NIPA) was identified as a binding partner of NPM-ALK. To identify the precise role of NIPA for NPM-ALK-driven lymp
Externí odkaz:
https://doaj.org/article/10e48b350181413cbc7c7d67f9d23de4
Autor:
Michal Kulinski, Annette Schmitt-Graeff, Tony A. Mueller, Christian Peschel, Melanie Boerries, Christine Dierks, Teresa Poggio, Irith Baumann, Justus Duyster, Milena Pantic, Michael L. Cleary, Nina Cabezas-Wallscheid, Khalid Shoumariyeh, Alina Mueller-Rudorf, Bernhard Kuster, Marie Follo, Hiroyuki Kawaguchi, Simone Lemeer, Miriam Erlacher, Detlev Schindler, Martina Rudelius, Anna Lena Illert, Tamina Rückert, Cathrin Klingeberg, Robert A.J. Oostendorp, Rouzanna Istvanffy, Jesus Duque-Afonso, Stefanie Kreutmair, Marcin W. Wlodarski, Charlotte M. Niemeyer, Dietmar Pfeifer, Geoffroy Andrieux, Robert Zeiser, Melissa Zwick
Publikováno v:
The Journal of Clinical Investigation
J Clin Invest
J Clin Invest
Inherited bone marrow failure syndromes (IBMFSs) are a heterogeneous group of disorders characterized by defective hematopoiesis, impaired stem cell function, and cancer susceptibility. Diagnosis of IBMFS presents a major challenge due to the large v
Autor:
Cathrin Klingeberg, Sophia Ehrenfeld, Anna Lena Illert, Martina Rudelius, Cornelius Miething, Dietmar Pfeifer, Nicolas Schneider, Pia Veratti, Falko Fend, Justus Duyster, Teresa Poggio, Robin Khan, Desiree M. Redhaber, Stefanie Kreutmair, Khalid Shoumariyeh, Leticia Quintanilla-Martinez
Publikováno v:
Oncogene. 39:1904-1913
Targeted expression of transgenes is essential for the accurate representation of human disease in in vivo models. Current approaches to generate conditional transgenic mouse models are cumbersome and not amenable to high-throughput analysis since th
Autor:
Anna Lena Illert, Claudia D. Baldus, Teresa Poggio, Cathrin Klingeberg, Peter Paschka, Allan Bradley, George S. Vassiliou, Alina Rudorf, Stefanie Kreutmair, Robert Zeiser, Tamina Rückert, Sivahari P. Gorantla, Justus Duyster, Anina Gengenbacher, Annette Schmitt-Graeff, Tony Andreas Müller
Publikováno v:
Blood
Activating mutations in FMS-like tyrosine kinase receptor-3 (FLT3) and Nucleophosmin-1 (NPM1) are most frequent alterations in acute myeloid leukemia (AML), and are often coincidental. The mutational status of NPM1 has strong prognostic relevance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5efddf9ea07046c4e5a4ab4bae2b447
https://europepmc.org/articles/PMC6659255/
https://europepmc.org/articles/PMC6659255/
Autor:
Stefanie Kreutmair, Marie Follo, Leticia Quintanilla-Martinez, Irene Gonzalez-Menendez, Dietmar Pfeifer, Melanie Boerries, Khalid Shoumariyeh, Cathrin Klingeberg, Justus Duyster, Cornelius Miething, Alexander Keller, Teresa Poggio, Suzanne D. Turner, Geoffroy Andrieux, Robert Zeiser, Falko Fend, Anna Lena Illert, Claudia Lengerke
Publikováno v:
Leukemia
While cancer stem cells are well established in certain hematologic and solid malignancies, their existence in T cell lymphoma is unclear and the origin of disease is not fully understood. To examine the existence of lymphoma stem cells, we utilized
Autor:
Khalid, Shoumariyeh, Nicolas, Schneider, Teresa, Poggio, Pia, Veratti, Sophia, Ehrenfeld, Desiree M, Redhaber, Robin, Khan, Dietmar, Pfeifer, Cathrin, Klingeberg, Stefanie, Kreutmair, Martina, Rudelius, Leticia, Quintanilla-Martinez, Falko, Fend, Anna L, Illert, Justus, Duyster, Cornelius, Miething
Publikováno v:
Oncogene. 39(9)
Targeted expression of transgenes is essential for the accurate representation of human disease in in vivo models. Current approaches to generate conditional transgenic mouse models are cumbersome and not amenable to high-throughput analysis since th
Autor:
Marie Follo, Melanie Boerries, Melissa Zwick, Justus Duyster, Stefanie Kreutmair, Annette Schmitt-Graeff, Anna Lena Illert, Milena Pantic, Cathrin Klingeberg, Irith Baumann, Bernhard Kuster, Hiroyuki Kawaguchi, Detlev Schindler, Khalid Shoumariyeh, Michal Kulinski, Geoffroy Andrieux, Nina Cabezas-Wallscheid, Dietmar Pfeifer, Rouzanna Istvanffy, Robert Zeiser, Martina Rudelius, Alina Rudorf, Miriam Erlacher, Christian Peschel, Michael D. Cleary, Tony Andreas Müller, Christine Dierks, Robert A.J. Oostendorp, Jesus Duque-Afonso, Teresa Poggio, Simone Lemeer, Charlotte M. Niemeyer, Marcin W. Wlodarski, Tamina Rückert
Publikováno v:
Blood. 134:3741-3741
Inherited bone marrow failure syndromes (IBMFS) are a heterogeneous group of disorders characterized by impaired stem cell function resulting in pancytopenia. Diagnosis of IBMFS presents a major challenge due to limited diagnostic tests and overlappi
Autor:
Stefanie Kreutmair, Cornelius Miething, J. Duyster, Cathrin Klingeberg, S. Ehrenfeld, D. M. Redhaber, N. Schneider, M. Rudelius, K. Shoumariyeh, F. Fend, T. Poggio, A L Illert
Publikováno v:
HemaSphere. 3:597-598
Autor:
Anna Lena Illert, Roswitha Tönnesmann, Cathrin Klingeberg, Philipp T. Meyer, Jason P. Holland, Helmut R. Maecke, Svetlana N. Rylova, Luigi Del Pozzo
Publikováno v:
Journal of Nuclear Medicine. 57:96-102
The CD30-specific antibody–drug conjugate, brentuximab vedotin, is approved for the treatment of relapsed, refractory Hodgkin lymphomas and systemic anaplastic large T-cell lymphomas. Multiple ongoing clinical trials are investigating brentuximab v
Autor:
Robin Khan, Cathrin Klingeberg, Justus Duyster, Cornelius Miething, Khalid Shoumariyeh, Sophia Ehrenfeld, Stefanie Kreutmair, Anna Lena Illert, Desiree Melanie Redhaber, Teresa Poggio
Publikováno v:
Blood. 132:1342-1342
Time- and tissue-specific expression of transgenes is essential for the accurate representation of human disease in in vivo models. To improve flexibility but also fidelity of ALK+ ALCL models, we developed new approaches enabling lineage specific ex