Výsledky vyhledávání - "Cathrin Hogrefe"

Improving Chemotherapy-Induced Peripheral Neuropathy in Patients with Breast or Colon Cancer after End of (Neo)adjuvant Therapy: Results from the Observational Study STEFANO

Autor: Mark-Oliver Zahn, Cathrin Hogrefe, Corinne Vannier, Norbert Marschner, Helmar C. Lehmann, Matthias Zaiss, Thomas Decker, Johanna Harde, Jens Uhlig

Publikováno v: Oncol Res Treat

Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect persisting after completion of neurotoxic chemotherapies. This observational study was designed to evaluate the effectiveness of the dietary supplement OnLife® (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5923b7b2baf1f6aa40e89e69616048eb
https://doi.org/10.1159/000519000

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First‐line pazopanib in intermediate‐ and poor‐risk patients with metastatic renal cell carcinoma: Final results of the FLIPPER trial

Autor: Patrick de Geeter, Marie Merling, Edwin Herrmann, Viktor Grünwald, Andrej Panic, Peter J. Goebell, Karin Potthoff, Michael Staehler, Norbert Marschner, Cathrin Hogrefe, Corinne Vannier

Temsirolimus has long been the only approved first-line standard of care (SOC) with overall survival (OS) benefit in poor-risk patients with advanced or metastatic renal cell cancer (mRCC). However, tyrosine kinase inhibitors are also commonly used i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c560f547cf753eaf5c3e82d3a07753
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/15109

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Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo

Autor: Jörg Fiedler, Heiko Reichel, Anita Ignatius, Cathrin Hogrefe, Rolf E. Brenner, Jana Riegger, Lutz Dürselen, Helga Joos, Frank Leucht

Publikováno v: The American Journal of Sports Medicine. 43:2822-2832

Background:Sport injuries of the knee often lead to posttraumatic arthritis. In addition to direct damage of the cartilage, trauma-associated intra-articular bleeding may cause hemarthrosis. Both blood exposure and trauma are known to induce cell dea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef5ec51f992583c5fd8a208dbf32ce9
https://doi.org/10.1177/0363546515602248

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An observational study to evaluate the potential of Onlife to improve chemotherapy-induced peripheral neuropathy: Final results of the STEFANO trial

Autor: Mark-Oliver Zahn, Helmar C. Lehmann, Matthias Zaiss, Norbert Marschner, Jens Uhlig, Johanna Harde, Thomas Decker, Cathrin Hogrefe, Corinne Vannier

Publikováno v: Journal of Clinical Oncology. 37:e23143-e23143

e23143 Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common, long-term side effect of many antineoplastic agents and has a detrimental impact on patients (pts)’ quality of life and functional activities of daily living. Current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::feba850fbe9c775dac8e1846307e4e7e
https://doi.org/10.1200/jco.2019.37.15_suppl.e23143

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Development of a New Biomechanically Defined Single Impact Rabbit Cartilage Trauma Model forIn Vivo-Studies

Autor: Cathrin Hogrefe, Anita Ignatius, Frank Leucht, Helga Joos, Heiko Reichel, Rolf E. Brenner, Lutz Dürselen, H. Schmitt

Publikováno v: Journal of Investigative Surgery. 25:235-241

Clinically oriented and easy to handle animal models are urgently needed to test pharmacologic treatment of cartilage trauma to reduce the resulting tissue damage by chondrocyte apoptosis and induction of matrix-degrading enzymes.To develop a biomech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a24ed56d11dca8d63ff37bfba3bad6
https://doi.org/10.3109/08941939.2011.630123

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Single impact cartilage trauma and TNF-α: interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches

Autor: Anita Ignatius, Lutz Dürselen, Vennila Maheswaran, Cathrin Hogrefe, Helga Joos, Rolf E. Brenner

Publikováno v: International journal of molecular medicine. 30(5)

Blunt trauma of articular cartilage, often resulting from accidents or sports injuries, is associated with local inflammatory reactions and represents a major risk factor for development of post-traumatic osteoarthritis. TNF-α is increased in synovi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72f7d6479a055eac381d9c7aa9d942e
https://pubmed.ncbi.nlm.nih.gov/22922824

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Single impact trauma in human early-stage osteoarthritic cartilage: implication of prostaglandin D2 but no additive effect of IL-1β on cell survival

Autor: Anita Ignatius, Lutz Dürselen, Helga Joos, Lucia Rieger, Rolf E. Brenner, Cathrin Hogrefe

Publikováno v: International journal of molecular medicine. 28(2)

Injury to articular cartilage is often associated with an inflammatory reaction and frequently results in the development of post-traumatic osteoarthritis (post-traumatic OA). Cell death, inflammation and loss of proteoglycans participate in these me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd91595346b18486a5c93fe1fb107f9
https://pubmed.ncbi.nlm.nih.gov/21567074

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