Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cathrin Eschbach"'
Autor:
Eva Hug, Hassan Jumaa, Markus Werner, Sebastian Herzog, Thomas Wossning, Hemin Faraidun, Fabian Kohler, Cathrin Eschbach, Alabbas Alkhatib
Publikováno v:
The Journal of Experimental Medicine
During murine B cell development, PI3 kinase inhibits Ig gene rearrangement by suppressing FoxO1, which mediates Ikaros mRNA splicing; Ikaros is needed for Ig gene recombination.
Somatic rearrangement of immunoglobulin (Ig) genes is a key step d
Somatic rearrangement of immunoglobulin (Ig) genes is a key step d
Autor:
Juliane Kofer, Hedda Wardemann, Cathrin Eschbach, Elias Hobeika, Sonja Meixlsperger, Eva Hug, Hassan Jumaa, Fabian Kohler
Publikováno v:
Immunity. 29(6):912-921
SummaryThe majority of early immature B cells express autoreactive B cell receptors (BCRs) that are, according to the current view, negatively selected to avoid the production of self-reactive antibodies. Here, we show that polyreactive BCRs, which r
Autor:
Cathrin Eschbach, Martina P. Bach, Roberta Pelanda, Ingrid Fidler, Hassan Jumaa, Fabian Kohler, Klaus Rajewsky
Publikováno v:
European journal of immunology. 41(8)
Antibody diversity is generated by a random gene recombination process with the inherent risk of the production of autoreactive specificities. The current view suggests that B cells expressing such specificities are negatively selected at an early de
Autor:
Michael Reth, Thomas Wossning, Hassan Jumaa, Martina P. Bach, Cathrin Eschbach, Rudolf Übelhart
Publikováno v:
Nature immunology. 11(8)
Developing B cells express distinct classes of B cell antigen receptors (BCRs) that differ in their heavy chain (HC). Although only muHC is expressed in early stages, deltaHC-containing BCRs dominate on the surface of mature B cells. The reason for t
Publikováno v:
Mechanisms of development. 98(1-2)
mRNA injection into the ventral blastomeres of Xenopus embryos of mRNA encoding Wnt pathway genes induces a secondary axis with complete head structures. To identify target genes of the pre-MBT dorsalization pathway that might be responsible for head
Autor:
Giselbert Hauptmann, Ajay B. Chitnis, Dirk Meyer, Iris Söll, Bernard Thisse, Salim Abdelilah-Seyfried, Wolfgang Driever, Christine Thisse, Kristin Bruk Artinger, Karen Lunde, Heinz-Georg Belting, Cathrin Eschbach
Publikováno v:
Scopus-Elsevier
Experts@Minnesota
Europe PubMed Central
Experts@Minnesota
Europe PubMed Central
The vertebrate midbrain-hindbrain boundary (MHB) organizes patterning and neuronal differentiation in the midbrain and anterior hindbrain. Formation of this organizing center involves multiple steps, including positioning of the MHB within the neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca207f86b7652d527634d025455c0c8f
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035168350&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035168350&partnerID=MN8TOARS