Zobrazeno 1 - 10
of 933
pro vyhledávání: '"Cathomen A"'
Autor:
Gorlo, Nicolas, Bamert, Samuel, Cathomen, Rafael, Käppeli, Gabriel, Müller, Mario, Reinhart, Tim, Stadler, Henriette, Shen, Hua, Cuniato, Eugenio, Tognon, Marco, Siegwart, Roland
In challenging terrains, constructing structures such as antennas and cable-car masts often requires the use of helicopters to transport loads via ropes. The swinging of the load, exacerbated by wind, impairs positioning accuracy, therefore necessita
Externí odkaz:
http://arxiv.org/abs/2312.01988
Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements
Autor:
Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C. Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler, Janine Reichenbach
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract CRISPR-based genome editing of pseudogene-associated disorders, such as p47 phox -deficient chronic granulomatous disease (p47 CGD), is challenged by chromosomal rearrangements due to presence of multiple targets. We report that interactions
Externí odkaz:
https://doaj.org/article/93b02712c21d4f31ac658ae71b0f19f4
Autor:
Tobias Bexte, Nawid Albinger, Ahmad Al Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Hadeer Mohamed Rasheed, Beate Anahita Jung, Sebastian Wolf, Raj Bhayadia, Thomas Oellerich, Jan-Henning Klusmann, Olaf Penack, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chimeric antigen receptor (CAR)-modified natural killer (NK) cells show antileukemic activity against acute myeloid leukemia (AML) in vivo. However, NK cell-mediated tumor killing is often impaired by the interaction between human leukocyte
Externí odkaz:
https://doaj.org/article/db49566912594bc5801e403512c3a9d3
Autor:
Sylwia Bobis-Wozowicz, Milena Paw, Michał Sarna, Sylwia Kędracka-Krok, Kinga Nit, Natalia Błażowska, Anna Dobosz, Ruba Hammad, Toni Cathomen, Ewa Zuba-Surma, Małgorzata Tyszka-Czochara, Zbigniew Madeja
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-27 (2024)
Abstract Background Stem cell-derived extracellular vesicles (EVs) are an emerging class of therapeutics with excellent biocompatibility, bioactivity and pro-regenerative capacity. One of the potential targets for EV-based medicines are cardiovascula
Externí odkaz:
https://doaj.org/article/b736b1cd2a814246a45a57a65b4e3a23
Autor:
Susanne Kessler, Bradly Burke, Geoffroy Andrieux, Jan Schinköthe, Lea Hamberger, Johannes Kacza, Shijun Zhan, Clara Reasoner, Taru S. Dutt, Maria Kaukab Osman, Marcela Henao-Tamayo, Julian Staniek, Jose Francisco Villena Ossa, Dalit T. Frank, Wenjun Ma, Reiner Ulrich, Toni Cathomen, Melanie Boerries, Marta Rizzi, Martin Beer, Martin Schwemmle, Peter Reuther, Tony Schountz, Kevin Ciminski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Jamaican fruit bats (Artibeus jamaicensis) naturally harbor a wide range of viruses of human relevance. These infections are typically mild in bats, suggesting unique features of their immune system. To better understand the immune response
Externí odkaz:
https://doaj.org/article/c051c263d7674a128f1b9588cd87ed8d
Autor:
Alexander Sturm, Grzegorz Jóźwiak, Marta Pla Verge, Laura Munch, Gino Cathomen, Anthony Vocat, Amanda Luraschi-Eggemann, Clara Orlando, Katja Fromm, Eric Delarze, Michał Świątkowski, Grzegorz Wielgoszewski, Roxana M. Totu, María García-Castillo, Alexandre Delfino, Florian Tagini, Sandor Kasas, Cornelia Lass-Flörl, Ronald Gstir, Rafael Cantón, Gilbert Greub, Danuta Cichocka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests (ASTs). Accelerated ASTs can identify effective an
Externí odkaz:
https://doaj.org/article/c91862c044384490bccd43ab68863853
Autor:
Ron Baik, M. Kyle Cromer, Steve E. Glenn, Christopher A. Vakulskas, Kay O. Chmielewski, Amanda M. Dudek, William N. Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P. Dever, Matthew H. Porteus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Genome editing by homology directed repair (HDR) is leveraged to precisely modify the genome of therapeutically relevant hematopoietic stem and progenitor cells (HSPCs). Here, we present a new approach to increasing the frequency of HDR in h
Externí odkaz:
https://doaj.org/article/4a155dde2a4841efb751cb4ae1cb657c
Autor:
Esposito, Federica, Dell’Aquila, Fabio, Rhiel, Manuel, Auricchio, Stefano, Chmielewski, Kay Ole, Andrieux, Geoffroy, Ferla, Rita, Horrach, Paula Sureda, Padmanabhan, Arjun, Di Cunto, Roberto, Notaro, Simone, Santeularia, Manel Llado, Boerries, Melanie, Dell’Anno, Margherita, Nusco, Edoardo, Padula, Agnese, Nutarelli, Sofia, Cornu, Tatjana I., Sorrentino, Nicolina Cristina, Piccolo, Pasquale, Trapani, Ivana, Cathomen, Toni, Auricchio, Alberto
Publikováno v:
In Cell Reports Medicine 16 July 2024 5(7)
Autor:
Bexte, Tobias, Botezatu, Lacramioara, Miskey, Csaba, Gierschek, Fenja, Moter, Alina, Wendel, Philipp, Reindl, Lisa Marie, Campe, Julia, Villena-Ossa, Jose Francisco, Gebel, Veronika, Stein, Katja, Cathomen, Toni, Cremer, Anjali, Wels, Winfried S., Hudecek, Michael, Ivics, Zoltán, Ullrich, Evelyn
Publikováno v:
In Molecular Therapy 3 July 2024 32(7):2357-2372
Autor:
Kath, Jonas, Franke, Clemens, Drosdek, Vanessa, Du, Weijie, Glaser, Viktor, Fuster-Garcia, Carla, Stein, Maik, Zittel, Tatiana, Schulenberg, Sarah, Porter, Caroline E., Andersch, Lena, Künkele, Annette, Alcaniz, Joshua, Hoffmann, Jens, Abken, Hinrich, Abou-el-Enein, Mohamed, Pruß, Axel, Suzuki, Masataka, Cathomen, Toni, Stripecke, Renata, Volk, Hans-Dieter, Reinke, Petra, Schmueck-Henneresse, Michael, Wagner, Dimitrios L.
Publikováno v:
In Blood 20 June 2024 143(25):2599-2611