Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cathleen Rich"'
Autor:
Helle Jacobsen, Cathleen Rich, Roberto Meza-Romero, Gregory G. Burrows, Richard E. Jones, Halina Offner, Alex Zamora, Jason M. Link, Arthur A. Vandenbark, Lars Fugger
The use of HLA class II-transgenic (Tg) mice has facilitated identification of antigenic T cell epitopes that may contribute to inflammation in T cell-mediated diseases such as rheumatoid arthritis and multiple sclerosis (MS). In this study, we compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922f27125ebb7df65690606a0f9f530c
https://ora.ox.ac.uk/objects/uuid:dda3eb8d-b751-4204-8d73-ee28f858913f
https://ora.ox.ac.uk/objects/uuid:dda3eb8d-b751-4204-8d73-ee28f858913f
Publikováno v:
Journal of Biological Chemistry. 283:20170-20180
We report the identification of three new collagen VI genes at a single locus on human chromosome 3q22.1. The three new genes are COL6A4, COL6A5, and COL6A6 that encode the α4(VI), α5(VI), and α6(VI) chains. In humans, the COL6A4 gene has been dis
Autor:
Arthur A. Vandenbark, Halina Offner, Maya Korat, Jason M. Link, Gregory G. Burrows, Cathleen Rich
Publikováno v:
Clinical Immunology. 123:95-104
Treatment of human autoimmune diseases such as multiple sclerosis (MS) will likely require agents that can prevent or reverse the inflammatory process that results in clinical relapses and disease progression. We evaluated the ability of a newly desi
Autor:
Cathleen Rich, Sandhya Subramanian, Michael Afentoulis, Richard E. Jones, Magdalena J. Polanczyk, Paul S. Cooke, Halina Offner, Arthur A. Vandenbark, Melissa A. Zakroczymski
Publikováno v:
The American Journal of Pathology. 165:2069-2077
Gender influences mediated by 17 beta-estradiol (E2) have been associated with susceptibility to and severity of autoimmune diseases such as diabetes, arthritis, and multiple sclerosis. In this regard, we have shown that estrogen receptor-alpha (Esr1
Autor:
Cathleen Rich, Dorian LaTocha, Yuan K. Chou, Abigail C. Buenafe, Dennis Bourdette, Willi K. Born, Gregory G. Burrows, J. M. Wands, Jianya Huan, Nicole Culbertson, Arthur A. Vandenbark, Halina Offner, Jason Link
Publikováno v:
Journal of Neuroscience Research. 77:670-680
The goal of this study was to establish an unlimited and standardized source of humanized myelin peptide-specific T cells for in vitro testing of biological function. Thus, we perpetuated myelin oligodendrocyte glycoprotein (MOG)-35-55 peptide-specif
Autor:
Chella S. David, Cathleen Rich, Thomas P. Finn, Rony Dahan, Arthur A. Vandenbark, Jason Link, Halina Offner, Richard E. Jones, Yuan K. Chou
Publikováno v:
Journal of Neuroscience Research. 78:100-114
Susceptibility to multiple sclerosis (MS) is associated genetically with human leucocyte antigen (HLA) class II alleles, including DRB1*1501, DRB5*0101, and DQB1*0602, and it is possible that these alleles contribute to MS through an enhanced ability
Autor:
Jianya Y, Huan, Roberto, Meza-Romero, Jeffery L, Mooney, Yuan K, Chou, David M, Edwards, Cathleen, Rich, Jason M, Link, Arthur A, Vandenbark, Dennis N, Bourdette, Hans-Peter, Bächinger, Gregory G, Burrows
Publikováno v:
Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986). 80(1)
Single-chain human recombinant T cell receptor ligands derived from the peptide binding/TCR recognition domain of human HLA-DR2b (DRA*0101/DRB1*1501) produced in Escherichia coli with and without amino-terminal extensions containing antigenic peptide
Publikováno v:
The Journal of biological chemistry. 283(29)
We report the identification of three new collagen VI genes at a single locus on human chromosome 3q22.1. The three new genes are COL6A4, COL6A5, and COL6A6 that encode the alpha4(VI), alpha5(VI), and alpha6(VI) chains. In humans, the COL6A4 gene has
Autor:
Christopher B. Little, Andrea Herzka, Justin M. Allen, Jamie Fitzgerald, D. Burkhardt, Cathleen Rich
Publikováno v:
Osteoarthritis and cartilage. 16(11)
Summary Objective A major clinical problem in Orthopaedics is the repair of traumatic articular cartilage lesions. The MRL/MpJ strain of mice has the remarkable ability to regenerate ear hole punch wounds seamlessly including the scarless replacement
Autor:
Chunhe Wang, Halina Offner, Johannes M. van Noort, Jason M. Link, Yuan K. Chou, Michael Afentoulis, Arthur A. Vandenbark, Cathleen Rich, Eric F. Wawrousek
Publikováno v:
Journal of neuroimmunology. 176(1-2)
Alpha B-crystallin (αB) is a small heat shock protein that is strongly up-regulated in multiple sclerosis (MS) brain tissue, and can induce strong T cell responses. Assessing a potential encephalitogenic function for αB protein in MS and experiment