Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cathleen M. Lind"'
Autor:
Shelley P Honnold, Russell R Bakken, Diana Fisher, Cathleen M Lind, Jeffrey W Cohen, Lori T Eccleston, Kevin B Spurgers, Radha K Maheshwari, Pamela J Glass
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104708 (2014)
Currently, there are no FDA-licensed vaccines or therapeutics for eastern equine encephalitis virus (EEEV) for human use. We recently developed several methods to inactivate CVEV1219, a chimeric live-attenuated eastern equine encephalitis virus (EEEV
Externí odkaz:
https://doaj.org/article/bfba8e133ca34452a25980fe14de6f99
Autor:
Kevin B. Spurgers, Cathleen M. Lind, Clarence R. Hurt, Vishwanath R. Lingappa, Lori T. Eccelston, Pamela J. Glass, Jeffrey W. Cohen
Publikováno v:
Journal of Virological Methods. 193:226-231
Venezuelan (VEEV), eastern, and western equine encephalitis viruses, members of the genus Alphavirus, are causative agents of debilitative and sometimes fatal encephalitis. Although human cases are rare, these viruses pose a threat to military person
Autor:
Mary Kate Hart, Michael D. Parker, Cathleen M. Lind, Patricia Garcia, Russell R. Bakken, Pamela J. Glass, Erin Jenkins, Donald L. Fine, Shannon S. Martin
Publikováno v:
Vaccine. 28:3143-3151
V3526, a genetically modified strain of Venezuelan equine encephalitis virus (VEEV), was formalin inactivated for evaluation as a next generation vaccine candidate for VEEV. In this study, we tested formalin-inactivated V3526 (fV3526) with and withou
Autor:
Christopher P. Locher, Cathleen M. Lind, Russell R. Bakken, Michael D. Parker, Connie S. Schmaljohn, Michelle J. Richards, Lesley C. Dupuy, Madan M. Paidhungat, Robert G. Whalen
Publikováno v:
Vaccine. 27:4152-4160
We employed directed molecular evolution to improve the cross-reactivity and immunogenicity of the Venezuelan equine encephalitis virus (VEEV) envelope glycoproteins. The DNA encoding the E1 and E2 proteins from VEEV subtypes IA/B and IE, Mucambo vir
Autor:
Cathleen M. Lind, Lawrence J. Sullivan, Matthew G. Lackemeyer, Sarah L. Norris, Jo Lynne Raymond, Douglas S. Reed, Scott Gamble, Nicole L. Garza
Publikováno v:
The Journal of Infectious Diseases. 196:441-450
Cynomolgus macaques exposed to an aerosol containing a virulent strain of eastern equine encephalitis (EEE) virus developed neurological signs indicating encephalitis that corresponded with the onset of fever and an elevated heart rate. Viremia was e
Autor:
Eric C. Mossel, Shelley P. Honnold, Lori T. Eccleston, Rebecca Erwin-Cohen, Kevin B. Spurgers, Russell R. Bakken, Jeffrey W. Cohen, Radha K. Maheshwari, Pamela J. Glass, Cathleen M. Lind
Publikováno v:
Virology Journal
Background Eastern equine encephalitis virus (EEEV) is an alphavirus with a case fatality rate estimated to be as high as 75 % in humans and 90 % in horses. Surviving patients often have long-lasting and severe neurological sequelae. At present, ther
Autor:
Shelley P. Honnold, Cathleen M. Lind, Eric C. Mossel, Russell R. Bakken, Kevin B. Spurgers, Diana Fisher, Pamela J. Glass, Lori T. Eccleston, Steven B. Bradfute, Radha K. Maheshwari, Jeffrey W. Cohen, Rebecca Erwin-Cohen
Publikováno v:
Virology Journal
Background Eastern equine encephalitis virus (EEEV), an arbovirus, is an important human and veterinary pathogen belonging to one of seven antigenic complexes in the genus Alphavirus, family Togaviridae. EEEV is considered the most deadly of the mosq
Autor:
Matthew G. Lackemeyer, Cathleen M. Lind, Douglas S. Reed, Lawrence J. Sullivan, Michael D. Parker, William D. Pratt
Publikováno v:
Vaccine. 23:3139-3147
Two live, attenuated strains of Venezuelan equine encephalitis virus (VEE), IE1150K and V3526, were administered to macaques to determine if they could elicit protection against an aerosol challenge with virulent VEE virus of the IE variety (VEEV-IE)
Publikováno v:
The Journal of Infectious Diseases. 189:1013-1017
Because Venezuelan equine encephalitis viruses (VEEVs) are infectious by aerosol, they are considered to be a biological-weapons threat. Nonhuman-primate models are needed to evaluate the efficacy of candidate vaccines. In the present study, cynomolg
Autor:
Kim Alterson, Jeanne Dudek, Jonathan Smith, Russell R. Bakken, Cathleen M. Lind, Kurt Kamrud, Pamela J. Glass, Michael D. Parker, Luis da Silva, James Barth, Jon O. Rayner, Mary Kate Hart, Max Custer, Douglas S. Reed, Gary Owens
Alphavirus replicons were evaluated as potential vaccine candidates for Venezuelan equine encephalitis virus (VEEV), western equine encephalitis virus (WEEV), or eastern equine encephalitis virus (EEEV) when given individually or in combination (V/W/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6c44dca357f02f538baae7767620db
https://europepmc.org/articles/PMC4178741/
https://europepmc.org/articles/PMC4178741/