Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cathleen Frein"'
Autor:
Reginald J. Claypool, Alexandra F. Freeman, Kenneth N. Olivier, Steven M. Holland, Jana P. Lovell, Cathleen Frein, Christa S. Zerbe, Victoria L. Anderson
Publikováno v:
Annals of the American Thoracic Society. 13:2169-2173
Mycobacterium kansasii usually causes chronic pulmonary infections in immunocompetent patients. In contrast, disseminated M. kansasii disease is commonly associated with advanced human immunodeficiency virus infection, but is reported infrequently in
Autor:
Elizabeth P. Sampaio, Alexandra F. Freeman, Martha Quezado, Amy P. Hsu, Lisa A. Barnhart, Victoria L. Anderson, Dirk Darnell, Christa S. Zerbe, Gulbu Uzel, Carah B. Santos, Cathleen Frein, Beatriz E. Marciano, Andrea Lisco, Eugene O. Major, Nick Adamo, Rohit K. Katial, Avindra Nath, Steven M. Holland, Mary E. Hanks
Publikováno v:
Clinical Infectious Diseases. 62:986-994
BACKGROUND Progressive multifocal leukoencephalopathy (PML) is a rare, severe, otherwise fatal viral infection of the white matter of the brain caused by the polyomavirus JC virus, which typically occurs only in immunocompromised patients. One patien
Autor:
Weiming Ouyang, Les R. Folio, V. Koneti Rao, Gulbu Uzel, Julie E. Niemela, Christine M. Seroogy, Eric Meffre, Bogdan Dumitriu, Kenneth N. Olivier, Bernice Lo, Jean Nicolas Schickel, Yu Zhang, Stefania Pittaluga, Yajesh Rampertaap, Luigi D. Notarangelo, Christopher Koh, Anna Huttenlocher, Joao Bosco Oliveira, Dat Q. Tran, Jason D. Hughes, Hye Sun Kuehn, David M. Frucht, Jennifer Stoddard, Thomas A. Fleisher, Michael J. Lenardo, Joshua J McElwee, Theo Heller, Steven M. Holland, Phillip Scheinberg, Susan Price, Helen C. Su, Danielle T. Avery, David E. Kleiner, Elissa K. Deenick, Stuart G. Tangye, Cathleen Frein
Publikováno v:
Science. 345:1623-1627
Beware of T cells that don't know how to stop During an infection, T cells divide extensively and secrete proteins that can severely damage tissues. But T cells know when to stop—they express proteins on their surface such as CTLA4, which put on th
Autor:
Caroline Smith, Janice M. Leung, Douglas B. Kuhns, Carissa Haney, Adrian M. Zelazny, Steven M. Holland, Kenneth N. Olivier, Cedar J. Fowler, Cathleen Frein, James H. Shelhamer, Andrea G. Huth, Janine Daub, Heather B. Root, Carolea Logun, Clare E. Bryant
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 187:1374-1381
Rationale: Pulmonary nontuberculous mycobacterial (PNTM) disease has increased over the past several decades, especially in older women. Despite extensive investigation, no consistent immunological abnormalities have been found. Using evidence from d
Autor:
Alexandra F. Freeman, Hannelore I. Bax, Reginald J. Claypool, Kenneth N. Olivier, Timothy Jancel, Li Ding, Christa S. Zerbe, Joseph Pechacek, Lisa A. Barnhart, B.E. Marciano, Amy P. Hsu, Christine Spalding, Elizabeth P. Sampaio, Ervand Kristosturyan, Cathleen Frein, Victoria L. Anderson, Lisa Boris, S.M. Holland
Publikováno v:
Journal of Clinical Immunology, 33(5), 991-1001. Springer New York
Patients with deficiency in the interferon gamma receptor (IFN-gamma R) are unable to respond properly to IFN-gamma and develop severe infections with nontuberculous mycobacteria (NTM). IFN-gamma and IFN-alpha are known to signal through STAT1 and ac
Autor:
Sergio D. Rosenzweig, Karen P. Lau, Cathleen Frein, Gulbu Uzel, Alexandra F. Freeman, E. Liana Falcone, Beatriz E. Marciano, Lisa A. Barnhart, Debra A. Long Priel, Danielle Fink, Victoria L. Anderson, John I. Gallin, Ladan Foruraghi, Harry L. Malech, Douglas B. Kuhns, Lynne Yockey, Suk See DeRavin, Sally Hunsberger, Samantha Kreuzburg, Kabir Matharu, Janine Daub, Li Ding, Christa S. Zerbe, Dirk Darnell, Steven M. Holland
Publikováno v:
The Journal of allergy and clinical immunology. 141(1)
Background Chronic granulomatous disease (CGD) is characterized by recurrent life-threatening bacterial and fungal infections and aberrant inflammation. Mutations in CYBB cause X-linked CGD and account for 65% to 70% of cases in Western countries. Ob
Autor:
Kimberly Romito, Martha Quezado, Kelly D. Stone, Chyi-Chia Richard Lee, Mukil Natarajan, Jeffrey B. Kopp, Muthulekha Swamydas, Wenjuan Gu, Steven M. Holland, Sally Hunsberger, David M. Chascsa, Julie E. Niemela, Cathleen Frein, Rachel Bishop, Morgan Similuk, Heidi H. Kong, Sarah K. Browne, Karen K. Winer, Theo Heller, Joseph Monsale, Shakuntala Rampertaap, Timothy J. Break, David M. Lang, Thomas L. Simcox, Elise M. N. Ferré, Thomas A. Fleisher, Gulbu Uzel, Lynne Yockey, Kenneth N. Olivier, Ilias Alevizos, Ariane Soldatos, Katherine R. Calvo, Jennifer Adjemian, Amanda L. Collar, Niki M. Moutsopoulos, David E. Kleiner, Stacey R. Rose, Peter D. Burbelo, Lindsey B. Rosen, Michail S. Lionakis, Amy P. Hsu, Angela Pham, Sergio D. Rosenzweig, Anamaria Bondici
Publikováno v:
JCI Insight. 1
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare primary immunodeficiency disorder typically caused by homozygous AIRE mutations. It classically presents with chronic mucocutaneous candidiasis and autoimmunity that pr
Autor:
Rebecca Prevots, Jennifer Adjemian, Steven M. Holland, Reginald J. Claypool, Kenneth N. Olivier, Janice M. Leung, Cathleen Frein, Cedar J. Fowler, Caroline Smith
Publikováno v:
American journal of respiratory and critical care medicine. 188(11)
To the Editor: Women over the age of 50 who lack antecedent structural lung damage have emerged as a growing population afflicted with pulmonary nontuberculous mycobacteria (PNTM) (1). A common body morphology among these women, who are often tall an