Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Cathleen E. Hanau"'
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APPLICATION OF HMBC AND HMQC-TOCSY NMR METHODS TO ASSIGN THE STRUCTURES OF BICYCLIC-PEPTIDE MIMETICS
Autor: Cathleen E. Hanau, Yvette M. Fobian, Kevin D. Moeller, D. André D'avignon
Publikováno v: Journal of Coordination Chemistry. 32:135-144
The structures of representative bicyclic peptides are confirmed through the NMR methods of HMBC and HMQC-TOCSY. Complete assignment of proton and carbon resonances is afforded by these two-dimensional NMR methods. HMQC-TOCSY is especially useful for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4946ac65046f0aae3f29b95cef74662f
https://doi.org/10.1080/00958979408024243
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4
The use of HMQC-TOCSY experiments for elucidating the structures of bicyclic lactams: Uncovering a surprise rearrangement in the synthesis of a key prophe building block
Autor: Kevin D. Moeller, Cathleen E. Hanau, Andre d'Avignon
Publikováno v: Tetrahedron Letters. 35:825-828
HMQC-TOCSY experiments were used to unequivocally assign the ring skeletons of several bicyclic lactams. This work demonstrated the power of these techniques for establishing the complete carbon connectivity of peptide building blocks with closely ov
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05de01bf7daef90305f715974afa631d
https://doi.org/10.1016/s0040-4039(00)75973-9
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5
ChemInform Abstract: Reductive Routes to Rigid Peptide Building Blocks: The Dependence of a Regioselective Imide Reduction on the Nature of an α-Alkoxy Substituent
Autor: Kevin D. Moeller, Cathleen E. Hanau
Publikováno v: ChemInform. 24
The reduction of several N-acylpyrrolidinones has been studied. The regioselectivity of the reductions was found to depend on the nature of the N-acyl group. In one example, the use of a sterically bulky triisopropylsiloxy substituent alpha to the N-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cdeb136de6872b599bfc0e2f44b9bd4
https://doi.org/10.1002/chin.199310198
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8
Reductive routes to rigid peptide building blocks: The dependence of a regioselective imide reduction on the nature of an α-alkoxy substituent
Autor: Cathleen E. Hanau, Kevin D. Moeller
Publikováno v: Tetrahedron Letters. 33:6041-6044
The reduction of several N-acylpyrrolidinones has been studied. The regioselectivity of the reductions was found to depend on the nature of the N-acyl group. In one example, the use of a sterically bulky triisopropylsiloxy substituent alpha to the N-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::376923c42416a67fd7c62e1e9029d083
https://doi.org/10.1016/s0040-4039(00)60001-1
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9
A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts
Autor: Khai Huynh, Min Yao, Nandini Kishore, Perry Thao D, Lee Albee, Julia Guzova, Sheri Bonar, Cindy Sommers, Catherine S. Tripp, Sumathy Mathialagan, J. Matthew Graneto, Scott Hauser, Cindy Mielke, Cathleen E. Hanau, Richard M. Weier
Publikováno v: The Journal of biological chemistry. 278(35)
NF-kappa B-induced gene expression contributes significantly to the pathogenesis of inflammatory diseases such as arthritis. I kappa B kinase (IKK) is the converging point for the activation of NF-kappa B by a broad spectrum of inflammatory agonists
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14886fb69011da098794e503c50f820d
https://pubmed.ncbi.nlm.nih.gov/12813046
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