Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cathleen, Dai"'
Autor:
Shashi Gujar, Sheila K. Singh, Paola Marcato, Carman A. Giacomantonio, Minomi Subapanditha, Chitra Venugopal, Barry E. Kennedy, Patrick J. Murphy, Mark Robert Hanes, Mohammad Saleh Ghassemi-Rad, Emma Martell, Cathleen Dai, Tanveer Sharif
Purpose:Stem-like cancer cells, with characteristic self-renewal abilities, remain highly refractory to various clinical interventions. As such, stemness-inhibiting entities, such as tumor suppressor p53, are therapeutically pursued for their antican
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44403ff8b861b7924f1922a76aca4d8
https://doi.org/10.1158/1078-0432.c.6528539.v1
https://doi.org/10.1158/1078-0432.c.6528539.v1
Autor:
Shashi Gujar, Sheila K. Singh, Paola Marcato, Carman A. Giacomantonio, Minomi Subapanditha, Chitra Venugopal, Barry E. Kennedy, Patrick J. Murphy, Mark Robert Hanes, Mohammad Saleh Ghassemi-Rad, Emma Martell, Cathleen Dai, Tanveer Sharif
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebc0d0790b2607f2715b368d924f459
https://doi.org/10.1158/1078-0432.22473554.v1
https://doi.org/10.1158/1078-0432.22473554.v1
Autor:
Shashi Gujar, Sheila K. Singh, Paola Marcato, Carman A. Giacomantonio, Minomi Subapanditha, Chitra Venugopal, Barry E. Kennedy, Patrick J. Murphy, Mark Robert Hanes, Mohammad Saleh Ghassemi-Rad, Emma Martell, Cathleen Dai, Tanveer Sharif
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c301267f31c6e5857e7dcb44af89d5
https://doi.org/10.1158/1078-0432.22473551
https://doi.org/10.1158/1078-0432.22473551
Autor:
Carman A. Giacomantonio, Mark Robert Hanes, Paola Marcato, Cathleen Dai, Barry E. Kennedy, Patrick J. Murphy, Chitra Venugopal, Shashi Gujar, Sheila K. Singh, Emma Martell, Minomi Subapanditha, Mohammad Saleh Ghassemi-Rad, Tanveer Sharif
Publikováno v:
Clinical Cancer Research. 25:2001-2017
Purpose: Stem-like cancer cells, with characteristic self-renewal abilities, remain highly refractory to various clinical interventions. As such, stemness-inhibiting entities, such as tumor suppressor p53, are therapeutically pursued for their antica
Autor:
Carman A. Giacomantonio, Shashi Gujar, Emma Martell, Patrick W. K. Lee, Hirendrasinh B. Parmar, Cathleen Dai, Nandini N. Margam, Tanveer Sharif, Mohammad Saleh Ghassemi-Rad, Roy Duncan, Mark Robert Hanes, Patrick J. Murphy
Publikováno v:
Autophagy. 15:686-706
Cancer stem-like cells (CSCs), a small population of pluripotent cells residing within heterogeneous tumor mass, remain highly resistant to various chemotherapies as compared to the differentiated cancer cells. It is being postulated that CSCs posses
Publikováno v:
Autophagy. 15(5)
Cancer stem-like cells (CSLCs) reside as a small population within tumors, which mostly contain a larger population of differentiated cells. With their unique self-renewing abilities, CSLCs remain refractory to various therapeutic interventions, whic
Autor:
Sheila K. Singh, Cathleen Dai, Ian C. G. Weaver, Kristen Lee, Shashi Gujar, Emma Martell, Tanveer Sharif, Mohammad Saleh Ghassemi-Rad
Publikováno v:
Cell Death and Disease, Vol 9, Iss 10, Pp 1-17 (2018)
Cancer cells with a less differentiated stem-like phenotype are more resistant to therapeutic manipulations than their differentiated counterparts, and are considered as one of the main causes of cancer persistence and relapse. As such, induction of
Autor:
Tanveer Sharif, Youra Kim, Patrick J. Murphy, Derek R. Clements, Barry E. Kennedy, Shashi Gujar, Emma Martell, Patrick W. K. Lee, Cathleen Dai
Publikováno v:
Autophagy. 13:264-284
Pluripotency is an important feature of cancer stem cells (CSCs) that contributes to self-renewal and chemoresistance. The maintenance of pluripotency of CSCs under various pathophysiological conditions requires a complex interaction between various
Autor:
Youra Kim, Shashi Gujar, Emma Martell, Patrick W. K. Lee, Barry E. Kennedy, Tanveer Sharif, Cathleen Dai
Publikováno v:
Pharmacological Research. 114:274-283
Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme for various physiological processes including energy metabolism, DNA repair, cell growth, and cell death. Many of these pathways are typically dysregulated in cancer cells, making NAD+
Autor:
Shashi Gujar, Emma Martell, Patrick W. K. Lee, Tanveer Sharif, Barry E. Kennedy, Cathleen Dai, Mohammad Saleh Ghassemi-Rad
Publikováno v:
Antioxidantsredox signaling. 30(6)
Significance: NAD+ is an essential redox cofactor in cellular metabolism and has emerged as an important regulator of a wide spectrum of disease conditions, most notably, cancers. As such, various strategies targeting NAD+ synthesis in cancers are in