Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cathie York-Defalco"'
Autor:
Cathie York-Defalco, Brianna Bender, Mausumee Guha, Doreen A. Miller, Jeffrey R. Crosby, Susan Gregory, Thomas P. Condon, Brett P. Monia, Richard S. Geary, James G. Karras, David Tung
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 321:938-946
The B7-family molecule CD86, expressed on the surface of pulmonary and thoracic lymph node antigen-presenting cells, delivers essential costimulatory signals for T-cell activation in response to inhaled allergens. CD86-CD28 signaling is involved in p
Autor:
Henri Sasmor, Boyd Conklin, Richard S. Geary, Ryan Morgan, Loanne Truong, Cathie York-Defalco, Oleg Khatsenko
Publikováno v:
Antisense and Nucleic Acid Drug Development. 10:35-44
An in situ single-pass perfusion model was used to assess the effect of chemical modification and length on permeability and absorption of various oligonucleotides in rat intestine. Phosphorothioate oligodeoxynucleotides (PS-ODN) were compared with o
Autor:
Joseph F. Johnston, Doreen Luther, K. Stecker, Nicholas M. Dean, Cathie York-DeFalco, Andrew T. Watt, Susan Murray, Jennifer K. Taylor, Seongjoon Koo, Hong Zhang, Jacqueline R. Wyatt
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 307(1)
Activation of the cell-surface receptor Fas can lead to apoptosis in parenchymal cells in the liver, and if severe enough, result in fulminant hepatic failure and animal death. In the present study, we have examined the roles played by the Bcl-2 fami