Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Cathie M Pfleger"'
Autor:
Chalita Washington, Rachel Chernet, Rewatee H Gokhale, Yesenia Martino-Cortez, Hsiu-Yu Liu, Ashley M Rosenberg, Sivan Shahar, Cathie M Pfleger
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008715 (2020)
Dysregulation of the Ras oncogene in development causes developmental disorders, "Rasopathies," whereas mutational activation or amplification of Ras in differentiated tissues causes cancer. Rabex-5 (also called RabGEF1) inhibits Ras by promoting Ras
Externí odkaz:
https://doaj.org/article/5aa33f8f592c4a1384e4c95b809cb481
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006198 (2016)
Hippo signaling acts as a master regulatory pathway controlling growth, proliferation, and apoptosis and also ensures that variations in proliferation do not alter organ size. How the pathway coordinates restricting proliferation with organ size cont
Externí odkaz:
https://doaj.org/article/ff9a42ba5fe3443c851058261d33de31
Autor:
Hsiu-Yu Liu, Cathie M Pfleger
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e32835 (2013)
Neurodegenerative diseases cause tremendous suffering for those afflicted and their families. Many of these diseases involve accumulation of mis-folded or aggregated proteins thought to play a causal role in disease pathology. Ubiquitinated proteins
Externí odkaz:
https://doaj.org/article/ae6c78e8a9f748dab9350c216dd7931f
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78880 (2013)
Alcohol-mediated cancers represent more than 3.5% of cancer-related deaths, yet how alcohol promotes cancer is a major open question. Using Drosophila, we identified novel interactions between dietary ethanol and loss of tumor suppressor components o
Externí odkaz:
https://doaj.org/article/4d4102965a4e4031ae87294b4bd1f336
Autor:
Rewatee, Gokhale, Cathie M, Pfleger
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1893
The Hippo Pathway comprises a vast network of components that integrate diverse signals including mechanical cues and cell surface or cell-surface-associated molecules to define cellular outputs of growth, proliferation, cell fate, and cell survival
Autor:
Cathie M. Pfleger, Rewatee H. Gokhale
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989096
The Hippo Pathway comprises a vast network of components that integrate diverse signals including mechanical cues and cell surface or cell-surface-associated molecules to define cellular outputs of growth, proliferation, cell fate, and cell survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89055e792b4c5561f164648b3f408265
https://doi.org/10.1007/978-1-4939-8910-2_1
https://doi.org/10.1007/978-1-4939-8910-2_1
Autor:
Hsiu-Yu Liu, Chalita Washington, Rachel Chernet, Sivan Shahar, Cathie M. Pfleger, Yesenia Martino-Cortez, Ashley M. Rosenberg, Rewatee H. Gokhale
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008715 (2020)
PLoS Genetics
PLoS Genetics
Dysregulation of the Ras oncogene in development causes developmental disorders, “Rasopathies,” whereas mutational activation or amplification of Ras in differentiated tissues causes cancer. Rabex-5 (also called RabGEF1) inhibits Ras by promoting
Autor:
Cathie M, Pfleger
Publikováno v:
Current topics in developmental biology. 123
The Hippo Pathway is a master regulatory network that regulates proliferation, cell growth, stemness, differentiation, and cell death. Coordination of these processes by the Hippo Pathway throughout development and in mature organisms in response to
Autor:
Theresa A, Reimels, Cathie M, Pfleger
Publikováno v:
Journal of visualized experiments : JoVE. (117)
Many parallels exist between the Drosophila and mammalian hematopoietic systems, even though Drosophila lack the lymphoid lineage that characterize mammalian adaptive immunity. Drosophila and mammalian hematopoiesis occur in spatially and temporally
Autor:
Madhavika N. Serasinghe, Sumaira Ali, Camila Rubio-Patiño, Mark P.A. Luna-Vargas, Jarvier N. Mohammed, Cindy Zou, Joshua R Kaminetsky, Ioana Abraham-Enachescu, Jerry E. Chipuk, Andrew P. Trotta, Cathie M. Pfleger, Rana Elkholi, Gavin P. McStay, Jesse D. Gelles
Publikováno v:
Mol Cell
Signaling diversity and subsequent complexity in higher eukaryotes is partially explained by one gene encoding a polypeptide with multiple biochemical functions in different cellular contexts. For example, mouse double minute 2 (MDM2) is functionally