Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Catherine Vilchèze"'
Autor:
Catherine Vilchèze, Bo Yan, Rosalyn Casey, Suzie Hingley-Wilson, Laurence Ettwiller, William R. Jacobs
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As the goal of a bacterium is to become bacteria, evolution has imposed continued selections for gene expression. The intracellular pathogen Mycobacterium tuberculosis, the causative agent of tuberculosis, has adopted a fine-tuned response to survive
Externí odkaz:
https://doaj.org/article/456985cdbd874ae9b543e739b57a54f3
Autor:
Syeda A. Hadi, Evan P. Brenner, Mitchell V. Palmer, W. Ray Waters, Tyler C. Thacker, Catherine Vilchèze, Michelle H. Larsen, William R. Jacobs, Srinand Sreevatsan
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1330 (2022)
Mycobacterium tuberculosis variant bovis (MBO) has one of the widest known mammalian host ranges, including humans. Despite the characterization of this pathogen in the 1800s and whole genome sequencing of a UK strain (AF2122) nearly two decades ago,
Externí odkaz:
https://doaj.org/article/30a2f3b7a0214e9cb72f4ef82e78c700
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The bacterial pathogen Mycobacterium tuberculosisM. tuberculosis
Externí odkaz:
https://doaj.org/article/c094f2897faf4d2f80ef114111ef6936
Autor:
Catherine Vilchèze
Publikováno v:
Applied Sciences, Vol 10, Iss 7, p 2278 (2020)
Eighty years after the introduction of the first antituberculosis (TB) drug, the treatment of drug-susceptible TB remains very cumbersome, requiring the use of four drugs (isoniazid, rifampicin, ethambutol and pyrazinamide) for two months followed by
Externí odkaz:
https://doaj.org/article/73711124fff04055be06ace06b51eed4
Autor:
Catherine Vilchèze, Jacqueline Copeland, Tracy L. Keiser, Torin Weisbrod, Jacqueline Washington, Paras Jain, Adel Malek, Brian Weinrick, William R. Jacobs
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Multidrug-resistant (MDR) tuberculosis, defined as tuberculosis resistant to the two first-line drugs isoniazid and rifampin, poses a serious problem for global tuberculosis control strategies. Lack of a safe and convenient model organism ha
Externí odkaz:
https://doaj.org/article/117a19d7561c4ccb89b01386464f0034
Autor:
Aaron Olsen, Yong Chen, Qingzhou Ji, Guofeng Zhu, Aruna Dharshan De Silva, Catherine Vilchèze, Torin Weisbrod, Weimin Li, Jiayong Xu, Michelle Larsen, Jinghang Zhang, Steven A. Porcelli, William R. Jacobs, John Chan
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT Tumor necrosis factor alpha (TNF) plays a critical role in the control of Mycobacterium tuberculosis, in part by augmenting T cell responses through promoting macrophage phagolysosomal fusion (thereby optimizing CD4+ T cell immunity by enhan
Externí odkaz:
https://doaj.org/article/bc38b2b8f2174103a7ba8842d17365ec
Autor:
JoAnn M. Tufariello, Christopher A. Kerantzas, Catherine Vilchèze, R. Brent Calder, Eric K. Nordberg, Jack A. Fischer, Travis E. Hartman, Eva Yang, Timothy Driscoll, Laura E. Cole, Robert Sebra, Shahina B. Maqbool, Alice R. Wattam, William R. Jacobs
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Mycobacterium haemophilum is an emerging pathogen associated with a variety of clinical syndromes, most commonly skin infections in immunocompromised individuals. M. haemophilum exhibits a unique requirement for iron supplementation to suppo
Externí odkaz:
https://doaj.org/article/90a51ee400054f14b7349d432b7286d1
Autor:
Travis Hartman, Brian Weinrick, Catherine Vilchèze, Michael Berney, Joanne Tufariello, Gregory M Cook, William R Jacobs
Publikováno v:
PLoS Pathogens, Vol 10, Iss 11, p e1004510 (2014)
In chronic infection, Mycobacterium tuberculosis bacilli are thought to enter a metabolic program that provides sufficient energy for maintenance of the protonmotive force, but is insufficient to meet the demands of cellular growth. We sought to unde
Externí odkaz:
https://doaj.org/article/fe4ac5f9252f4e60bf045c208f6f39da
Autor:
JoAnn M. Tufariello, Adel A. Malek, Catherine Vilchèze, Laura E. Cole, Hannah K. Ratner, Pablo A. González, Paras Jain, Graham F. Hatfull, Michelle H. Larsen, William R. Jacobs
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Genetic engineering has contributed greatly to our understanding of Mycobacterium tuberculosis biology and has facilitated antimycobacterial and vaccine development. However, methods to generate M. tuberculosis deletion mutants remain labor-
Externí odkaz:
https://doaj.org/article/1268cf3ded4a4c76a1dc124fd7328d8a
Autor:
Claudia Cortesia, Catherine Vilchèze, Audrey Bernut, Whendy Contreras, Keyla Gómez, Jacobus de Waard, William R. Jacobs, Laurent Kremer, Howard Takiff
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Effective and economical mycobactericidal disinfectants are needed to kill both Mycobacterium tuberculosis and non-M. tuberculosis mycobacteria. We found that acetic acid (vinegar) efficiently kills M. tuberculosis after 30 min of exposure t
Externí odkaz:
https://doaj.org/article/a74ba4c9129c44a99703ca864aaecf65