Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Catherine Vaurs-Barrière"'
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Akademický článek
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage
Autor: Elisa Le Boiteux, Franck Court, Pierre‐Olivier Guichet, Catherine Vaurs‐Barrière, Isabelle Vaillant, Emmanuel Chautard, Pierre Verrelle, Bruno M. Costa, Lucie Karayan‐Tapon, Anne Fogli, Philippe Arnaud
Publikováno v: Molecular Oncology, Vol 15, Iss 8, Pp 1995-2010 (2021)
In human, the 39 coding HOX genes and 18 referenced noncoding antisense transcripts are arranged in four genomic clusters named HOXA, B, C, and D. This highly conserved family belongs to the homeobox class of genes that encode transcription factors r
Externí odkaz: https://doaj.org/article/fed95548f2564556b60979aca372b0ee
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2
L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus
Autor: Marie-Elisa Pinson, Franck Court, Aymeric Masson, Yoan Renaud, Allison Fantini, Ophélie Bacoeur-Ouzillou, Marie Barriere, Bruno Pereira, Pierre-Olivier Guichet, Emmanuel Chautard, Lucie Karayan-Tapon, Pierre Verrelle, Philippe Arnaud, Catherine Vaurs-Barrière
Publikováno v: Human Molecular Genetics
Human Molecular Genetics, In press
Human Molecular Genetics, 2022, 31 (15), pp.2606-2622. ⟨10.1093/hmg/ddac056⟩
Besides the consequences of retrotransposition, long interspersed element 1 (L1) retrotransposons can affect the host genome through their antisense promoter. In addition to the sense promoter, the evolutionarily recent L1 retrotransposons, which are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76312db2c614ceea8bf32459fa44595
https://doi.org/10.1093/hmg/ddac056
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3
Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms
Autor: Mélanie Müller-Barthélémy, Elisa Le Boiteux, Franck Court, Julian Biau, Lucie Karayan-Tapon, Toufic Khalil, Pierre Verrelle, Philippe Arnaud, Jean-Louis Kemeny, Anne Fogli, Catherine Vaurs-Barrière, Bruno Pereira, Emmanuel Chautard
Publikováno v: Genome Research
Genome Research, 2019, 29 (10), pp.1605-1621. ⟨10.1101/gr.249219.119⟩
Genome Research, Cold Spring Harbor Laboratory Press, 2019, 29 (10), pp.1605-1621. ⟨10.1101/gr.249219.119⟩
In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a976cd21f9127bb91cbb3859bc871cd6
https://doi.org/10.1101/gr.249219.119
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4
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage
Autor: Catherine Vaurs-Barrière, Elisa Le Boiteux, Isabelle Vaillant, Anne Fogli, Bruno M. Costa, Pierre Verrelle, Emmanuel Chautard, Lucie Karayan-Tapon, Pierre-Olivier Guichet, Franck Court, Philippe Arnaud
Publikováno v: Molecular Oncology
Molecular Oncology, Elsevier, 2021, ⟨10.1002/1878-0261.12944⟩
Molecular Oncology, 2021, ⟨10.1002/1878-0261.12944⟩
Molecular Oncology, Vol 15, Iss 8, Pp 1995-2010 (2021)
In human, the 39 coding HOX genes and 18 referenced noncoding antisense transcripts are arranged in four genomic clusters named HOXA, B, C, and D. This highly conserved family belongs to the homeobox class of genes that encode transcription factors r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c663b7f53d6cfea16f45f720db7c7867
https://hal.archives-ouvertes.fr/hal-03172071/document
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6
Most of transcriptional alterations in glioma result from DNA-methylation independent mechanisms
Autor: Pierre Verrelle, Lucie Karayan-Tapon, Emmanuel Chautard, Anne Fogli, Frank Court, Bruno Pereira, Jean-Louis Kemeny, E. Le Boiteux, Catherine Vaurs-Barrière, M. Müller-Barthelemy, Toufic Khalil, Julian Biau, Philippe Arnaud
BackgroundAberrant DNA methylation is a cancer cell feature that is commonly associated with transcriptional alterations. However, the primary role of this defect in the genome-wide cancer-associated gene deregulation is not clear. Here, we evaluated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17b0d42885633e9523521a8ff13440a
https://doi.org/10.1101/516997
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7
CLIFinder: Identification of LINE-1 Chimeric Transcripts in RNA-seq data
Autor: Catherine Vaurs-Barrière, Philippe Arnaud, Marie-Elisa Pinson, Romain Pogorelcnik, Franck Court
Publikováno v: Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2017, ⟨10.1093/bioinformatics/btx671⟩
Bioinformatics, 2017, ⟨10.1093/bioinformatics/btx671⟩
Summary L1 Chimeric Transcripts (LCTs) are initiated by repeated LINE-1 element antisense promoters and include the L1 5′UTR sequence in antisense orientation followed by the adjacent genomic region. LCTs have been characterized mainly using bioinf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012e1e862d48c2d57bf2154684eab585
https://hal.uca.fr/hal-01629422/document
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8
OXIDATIVE STRESS AND MITOCHONDRIAL DYNAMICS MALFUNCTION ARE LINKED IN PELIZAEUS-MERZBACHER DISEASE
Autor: Odile Boespflug-Tanguy, Marie-Noëlle Bonnet-Dupeyron, Mélina Bégou, Johan Auwerx, Jone López-Erauskin, Aurora Pujol, Nathalie Launay, Céline Guéret-Gonthier, Catherine Vaurs-Barrière, Pablo Ranea-Robles, Patrizia Bianchi, Stéphane Fourcade, Bérengère Petit, Laia Morató, Montserrat Ruiz, Cristina Guilera
Publikováno v: Brain Pathology
Brain Pathology, 2017, ⟨10.1111/bpa.12571⟩
Brain Pathology, Wiley, 2017, ⟨10.1111/bpa.12571⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Brain Pathology, Wiley, 2017, 〈10.1111/bpa.12571〉
Pelizaeus‐Merzbacher disease (PMD) is a fatal hypomyelinating disorder characterized by early impairment of motor development, nystagmus, choreoathetotic movements, ataxia and progressive spasticity. PMD is caused by variations in the proteolipid p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21be927e5d376dd6689ba3c95b010238
https://hal.uca.fr/hal-01662573
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9
Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis
Autor: Bruno Pereira, Marie-Véronique Demattei, Pierre Verrelle, Jean-Louis Kemeny, Anne Fogli, Julian Biau, Nathalie Grandin, Philippe Arnaud, Emmanuel Chautard, Laetitia Corset, Catherine Godfraind, Michel Charbonneau, Catherine Vaurs-Barrière, T. Khalil
Publikováno v: Journal of Neuro-Oncology
Journal of Neuro-Oncology, 2017, 135 (2), pp.381-390. ⟨10.1007/s11060-017-2585-7⟩
Journal of Neuro-Oncology, Springer Verlag, 2017, 135 (2), pp.381-390. ⟨10.1007/s11060-017-2585-7⟩
Journal of Neuro-Oncology, Springer Verlag, 2017, 135 (2), pp.381-390. 〈10.1007/s11060-017-2585-7〉
International audience; Human malignant gliomas exhibit acquisition of either one of two telomere maintenance mechanisms, resulting from either reactivation of telomerase expression or activation of an alternative lengthening of telomeres (ALT) mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbc3dffe5c44741fcb701c178712691
https://hal.science/hal-01643036
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10
The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival
Autor: Bruno M. Costa, Jean-Louis Kemeny, Pierre Verrelle, Catherine Vaurs-Barrière, Afonso A. Pinto, Bruno Pereira, Lucie Karayan-Tapon, Mélanie Müller-Barthélémy, Franck Court, Julian Biau, Anne Fogli, Philippe Arnaud, Emmanuel Chautard, Toufic Khalil
Publikováno v: Carcinogenesis
Carcinogenesis, Oxford University Press (OUP), 2016, 37 (2), pp.169-176. ⟨10.1093/carcin/bgv251⟩
Carcinogenesis, 2016, 37 (2), pp.169-176. ⟨10.1093/carcin/bgv251⟩
Carcinogenesis, Oxford University Press (OUP), 2016, 37 (2), pp.169-176. 〈10.1093/carcin/bgv251〉
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Malignant gliomas are the most common primary brain tumors. Grade III and IV gliomas harboring wild-type IDH1/2 are the most aggressive. In addition to surgery and radiotherapy, concomitant and adjuvant chemotherapy with temozolomide (TMZ) significan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da31edcecef0085531ad162f18e18d
https://hal.uca.fr/hal-01629349
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