Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Catherine Tjan"'
Autor:
Joseph Vijai, Kenneth Offit, Michael F. Berger, Jonathan W. Lee, Erica S. Kaufmann, Robin Brenner, Yelena Kemel, Angela G. Arnold, Mark E. Robson, Steven D. Leach, Maeve A. Lowery, Vignesh Ravichandran, Gokce Askan, Kenneth H. Yu, Ghassan K. Abou-Alfa, Hannah Maynard, David S. Klimstra, Marinela Capanu, Christina M. Covington, David M. Hyman, Winston Wong, Eileen M. O'Reilly, Christine A. Iacobuzio-Donahue, Peter J. Allen, Semanti Mukherjee, Zsofia K. Stadler, Emmet Jordan, Catherine Tjan, Ahmet Zehir, Erin E. Salo-Mullen, Anna M. Varghese, David P. Kelsen, Diana Mandelker
Publikováno v:
Journal of the National Cancer Institute. 110(10)
BACKGROUND: Identification of pathogenic germline alterations (PGAs) has important clinical and therapeutic implications in pancreas cancer. We performed comprehensive germline testing (GT) in an unselected prospective cohort of patients with exocrin
Autor:
Marina Shcherba, Maeve A. Lowery, Audrey Hamilton, Zoe Goldberg, Robin Brenner, Erica S. Kaufmann, Kenneth H. Yu, Richard K. G. Do, Jia Li, Catherine Tjan, Nitya Raj, Alice Zervoudakis, Simon Mantha, Elizabeth Won, Antonio Ucar, Geoffrey Y. Ku, Eileen M. O'Reilly
Publikováno v:
Journal of Clinical Oncology. 36:405-405
405 Background: PEGPH20 (P) degrades hyaluronan (HA), a key component of pancreatic adenocarcinoma (PDAC) tumor microenvironment, leading to reduction of tumor interstitial pressure, decompression of tumor blood vessels and improvement in delivery of
Autor:
Catherine Tjan, Keith T. Flaherty, James M. Roach, Silva Krause, Eileen M. O'Reilly, Paul J. E. Miller, Darrell Nix, Kenneth H. Yu, Molly Rosano, William Avery, David P. Ryan, Julie Wolf
Publikováno v:
The Oncologist
Lessons LearnedDespite the compelling preclinical rationale of evaluating the genetically engineered heparin derivative, necuparanib, combined with standard therapy in metastatic pancreas adenocarcinoma, the results were ultimately disappointing. Saf