Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Catherine Strassel"'
Publikováno v:
Platelets, Vol 33, Iss 6, Pp 833-840 (2022)
Glycoprotein V (GPV) is a highly expressed 82 KDa platelet surface transmembrane protein which is loosely attached to the GPIb-IX complex. Despite remaining questions concerning its function, GPV presents several unique features which have repercussi
Externí odkaz:
https://doaj.org/article/76415790333d41a4915a3b3d92b5c83e
Autor:
Alicia Bornert, Julie Boscher, Fabien Pertuy, Anita Eckly, David Stegner, Catherine Strassel, Christian Gachet, François Lanza, Catherine Léon
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Platelets are produced by bone marrow megakaryocytes through cytoplasmic protrusions, named native proplatelets (nPPT), into blood vessels. Proplatelets also refer to protrusions observed in megakaryocyte culture (cPPT) that are morphologically diffe
Externí odkaz:
https://doaj.org/article/9293cffb03a54b7689d117281a64e7d2
Autor:
Athanasia Stoupa, Frédéric Adam, Dulanjalee Kariyawasam, Catherine Strassel, Sanjay Gawade, Gabor Szinnai, Alexandre Kauskot, Dominique Lasne, Carsten Janke, Kathiresan Natarajan, Alain Schmitt, Christine Bole‐Feysot, Patrick Nitschke, Juliane Léger, Fabienne Jabot‐Hanin, Frédéric Tores, Anita Michel, Arnold Munnich, Claude Besmond, Raphaël Scharfmann, François Lanza, Delphine Borgel, Michel Polak, Aurore Carré
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-18 (2018)
Abstract The genetic causes of congenital hypothyroidism due to thyroid dysgenesis (TD) remain largely unknown. We identified three novel TUBB1 gene mutations that co‐segregated with TD in three distinct families leading to 1.1% of TUBB1 mutations
Externí odkaz:
https://doaj.org/article/9f89d1aa4ab044b1b23872b473386b2b
Autor:
Nathalie Brouard, Camille Jost, Nadine Matthias, Camille Albrecht, Sébastien Egard, Poojabahen Gandhi, Catherine Strassel, Tomoko Inoue, Daisuke Sugiyama, Paul J. Simmons, Christian Gachet, Francois Lanza
Publikováno v:
Blood Advances, Vol 1, Iss 21, Pp 1854-1866 (2017)
Abstract: The fetal liver is the site of a major expansion of the hematopoietic stem cell (HSC) pool and is also a privileged organ to study megakaryocyte progenitor differentiation. We identified in the mouse fetal liver at day 13.5 a discrete strom
Externí odkaz:
https://doaj.org/article/59da54ae990c4a8194709f551150303a
Autor:
Lea Mallo, Valentin Do Sacramento, Christian Gachet, Susan Chan, Philippe Kastner, François Lanza, Henri de la Salle, Catherine Strassel
Publikováno v:
Reports, Vol 4, Iss 1, p 7 (2021)
In vitro, the differentiation of megakaryocytes (MKs) is improved by aryl-hydrocarbon receptor (AHR) antagonists such as StemRegenin 1 (SR1), an effect physiologically recapitulated by the presence of stromal mesenchymal cells (MSC). This inhibition
Externí odkaz:
https://doaj.org/article/70bdc1267848460592e7833bc9108149
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
The severely decreased platelet counts (10–30. 103 platelets/μL) frequently observed in patients undergoing chemotherapy, radiation treatment, or organ transplantation are associated with life-threatening increased bleeding risks. To circumvent th
Externí odkaz:
https://doaj.org/article/92be1c08815b4dca92e7dc74bb7f60cd
Autor:
Salima Benbarche, Catherine Strassel, Catherine Angénieux, Léa Mallo, Monique Freund, Christian Gachet, François Lanza, Henri de la Salle
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Gene profiling studies have indicated that in vitro differentiated human megakaryocytes express the receptor for IL-21 (IL-21R), an immunostimulatory cytokine associated with inflammatory disorders and currently under evaluation in cancer therapy. Th
Externí odkaz:
https://doaj.org/article/225ac4edc08542f2abeb7e61ade5bc2f
Autor:
Catherine Strassel, Anita Eckly, Catherine Léon, Claire Petitjean, Monique Freund, Jean-Pierre Cazenave, Christian Gachet, François Lanza
Publikováno v:
Haematologica, Vol 94, Iss 6 (2009)
Background Giant platelets and thrombocytopenia are invariable defects in the Bernard-Soulier syndrome caused by deficiency of the GPIb-V-IX complex, a receptor for von Willebrand factor supporting platelet adhesion to the damaged arterial wall. Vari
Externí odkaz:
https://doaj.org/article/c3b18d14606244efba3b70bc546b4488
Autor:
Catherine Strassel, Séverine Nolli, Sylvie Dunoyer-Geindre, Pierre Fontana, Jean-Luc Reny, Alix Garcia
Publikováno v:
Thrombosis and Haemostasis
Background Several platelet-derived microRNAs are associated with platelet reactivity (PR) and clinical outcome in cardiovascular patients. We previously showed an association between miR-204-5p and PR in stable cardiovascular patients, but data on f
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 204:971-980
Resume Les plaquettes sanguines sont des elements anuclees du sang. D’un diametre de 2 a 3 μm, ce sont les plus petits elements figures du sang. Alors que leur role principal est d’arreter ou prevenir les saignements, elles sont egalement impliq