Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Catherine Stenson-Cox"'
Autor:
Louise Murphy, Marie A. Punchard, Valerie Barron, Eoin D. O'Cearbhaill, Abhay Pandit, E. Lyons, Peter E. McHugh, Catherine Stenson-Cox, Sarah L. Gundy
Publikováno v:
Journal of Biomechanics. 40:3146-3154
In vivo, endothelial cells (EC) are constantly exposed to the haemodynamic forces (HF) of pressure, wall shear stress and hoop stress. The main aim of this study was to design, create and validate a novel perfusion bioreactor capable of delivering sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5c1b15e35bc8b2f8a3d7088c2fdf0b
https://doi.org/10.1016/j.jbiomech.2007.03.029
https://doi.org/10.1016/j.jbiomech.2007.03.029
Publikováno v:
Biochemical and Biophysical Research Communications. 345:608-616
Apoptosis involves a cascade of biochemical and morphological changes resulting in the systematic disintegration of the cell. Caspases are central mediators of this process. Supporting and primary roles for serine proteases as pro-apoptotic mediators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6f6710b88cefda5de11d4b4cfc5c6f
https://doi.org/10.1016/j.bbrc.2006.04.147
https://doi.org/10.1016/j.bbrc.2006.04.147
Publikováno v:
Current Genomics. 5:287-297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ec0afb7950308d444219e279de96b0f
https://doi.org/10.2174/1389202043349327
https://doi.org/10.2174/1389202043349327
Publikováno v:
Biochemical Pharmacology. 66:1469-1474
Proteolysis is central to the systematic cellular degradation that occurs during apoptosis. Predominantly, caspases have been studied in this regard. However, increasing evidence suggests that certain serine proteases may also play a significant role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45fb4af695bb6e0c7f5bab8ed451e0c
https://doi.org/10.1016/s0006-2952(03)00499-4
https://doi.org/10.1016/s0006-2952(03)00499-4
Autor:
Afshin Samali, Adrienne M. Gorman, Catherine Stenson-Cox, Ronan T. Bree, Lucy Byrnes, Maura Grealy
Publikováno v:
Biogerontology. 3:195-206
Cellular longevity refers to the lifespan of an individual cell. Normal cells have a finite lifespan and typically die by undergoing apoptosis, or enter into a state of irreversible growth arrest, termed replicative senescence, at the end of that lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a6a9b6b18b9a27529268f48342e548
https://doi.org/10.1023/a:1016299812327
https://doi.org/10.1023/a:1016299812327
Autor:
Marie A. Punchard, Joseph N. Mackle, Catherine Stenson-Cox, Eoin D. O'Cearbhaill, Peter E. McHugh, Valerie Barron, Terry J. Smith
Publikováno v:
Annals of biomedical engineering. 37(7)
Percutaneous stent implantation has revolutionized the clinical treatment of occluded arteries. Nevertheless, there is still a large unmet need to prevent re-occlusion after implantation. Consequently, a niche exists for a cost-effective pre-clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a15544a2903b9049111fc8b1ad4cb54
https://pubmed.ncbi.nlm.nih.gov/19408120
https://pubmed.ncbi.nlm.nih.gov/19408120
Autor:
Catherine Stenson-Cox, Timothy O'Brien, Isabella Pörn-Ares, Afshin Samali, Aideen O’Doherty, Janice L. V. Reeve, Mikko P.S. Ares
Publikováno v:
Biochemical and biophysical research communications. 356(3)
Oxidized low density lipoprotein (oxLDL) contributes to the pathophysiology of atherosclerosis, partly by altering gene expression in vascular cells. Here, we show 221 genes differentially regulated by oxLDL in coronary artery smooth muscle cells (CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d21740dcbf3be7ed512b22dfba86f9
https://pubmed.ncbi.nlm.nih.gov/17374365
https://pubmed.ncbi.nlm.nih.gov/17374365
Autor:
E. McLucas, Peter E. McHugh, D. O'Mahoney, Claire Brougham, Valerie Barron, Karen M. Coghlan, Catherine Stenson-Cox
Publikováno v:
Articles
In vivo, endothelial cells are constantly exposed to pulsatile shear and tensile stresses. The main aim of this study was to design and build a physiological simulator, which reproduced homogenous strain profiles of the tensile strain experienced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2519929bbf51c9ebfe8407c152ebe4a
https://arrow.tudublin.ie/context/biodevart/article/1007/viewcontent/auto_convert.pdf
https://arrow.tudublin.ie/context/biodevart/article/1007/viewcontent/auto_convert.pdf
Autor:
Martin E. O’Mahoney, Susan E. Logue, Una FitzGerald, Catherine Stenson-Cox, Afshin Samali, Eva Szegezdi
Publikováno v:
Annals of the New York Academy of Sciences. 1010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03e69e6b025b9da437e2ec7e7ba450f
https://pubmed.ncbi.nlm.nih.gov/15033818
https://pubmed.ncbi.nlm.nih.gov/15033818
Publikováno v:
Annals of biomedical engineering. 31(9)
Heart disease is a major cause of death in the Western world. In the past three decades there has been a number of improvements in artificial devices and surgical techniques for cardiovascular disease; however, there is still a need for novel devices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576ecc5aef2b3b2b6fa6aa7f836d5cd0
https://pubmed.ncbi.nlm.nih.gov/14582605
https://pubmed.ncbi.nlm.nih.gov/14582605