Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Catherine Schramm"'
Autor:
Catherine Schramm, Camille Charbonnier, Aline Zaréa, Morgane Lacour, David Wallon, CNRMAJ collaborators, Anne Boland, Jean-François Deleuze, Robert Olaso, ADES consortium, Flora Alarcon, Dominique Campion, Grégory Nuel, Gaël Nicolas
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/4e5c4247d44444c698c81ce1e6caf234
Autor:
Catherine Schramm, Camille Charbonnier, Aline Zaréa, Morgane Lacour, David Wallon, CNRMAJ collaborators, Anne Boland, Jean-François Deleuze, Robert Olaso, ADES consortium, Flora Alarcon, Dominique Campion, Grégory Nuel, Gaël Nicolas
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background Alzheimer disease (AD) is a common complex disorder with a high genetic component. Loss-of-function (LoF) SORL1 variants are one of the strongest AD genetic risk factors. Estimating their age-related penetrance is essential before
Externí odkaz:
https://doaj.org/article/40ed3c4b271e4576bb2578794dbaf6f2
Autor:
Anne Rovelet-Lecrux, Sebastien Feuillette, Laetitia Miguel, Catherine Schramm, Ségolène Pernet, Olivier Quenez, Isabelle Ségalas-Milazzo, Laure Guilhaudis, Stéphane Rousseau, Gaëtan Riou, Thierry Frébourg, Dominique Campion, Gaël Nicolas, Magalie Lecourtois
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-22 (2021)
Abstract The SorLA protein, encoded by the SORL1 gene, is a major player in Alzheimer’s disease (AD) pathophysiology. Functional and genetic studies demonstrated that SorLA deficiency results in increased production of Aβ peptides, and thus a high
Externí odkaz:
https://doaj.org/article/cd8485a3038f453c88b98b96329944db
Autor:
Claudia Modenato, Kuldeep Kumar, Clara Moreau, Sandra Martin-Brevet, Guillaume Huguet, Catherine Schramm, Martineau Jean-Louis, Charles-Olivier Martin, Nadine Younis, Petra Tamer, Elise Douard, Fanny Thébault-Dagher, Valérie Côté, Audrey-Rose Charlebois, Florence Deguire, Anne M. Maillard, Borja Rodriguez-Herreros, Aurèlie Pain, Sonia Richetin, p11.2 European Consortium, Simons Searchlight Consortium, Lester Melie-Garcia, Leila Kushan, Ana I. Silva, Marianne B. M. van den Bree, David E. J. Linden, Michael J. Owen, Jeremy Hall, Sarah Lippé, Mallar Chakravarty, Danilo Bzdok, Carrie E. Bearden, Bogdan Draganski, Sébastien Jacquemont
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Many copy number variants (CNVs) confer risk for the same range of neurodevelopmental symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date neuroimaging studies have typically been carried out one mutation at a
Externí odkaz:
https://doaj.org/article/3a9bd9d8d1da4a4690dbd8a4538abf20
Autor:
Clara A. Moreau, Sebastian G. W. Urchs, Kumar Kuldeep, Pierre Orban, Catherine Schramm, Guillaume Dumas, Aurélie Labbe, Guillaume Huguet, Elise Douard, Pierre-Olivier Quirion, Amy Lin, Leila Kushan, Stephanie Grot, David Luck, Adrianna Mendrek, Stephane Potvin, Emmanuel Stip, Thomas Bourgeron, Alan C. Evans, Carrie E. Bearden, Pierre Bellec, Sebastien Jacquemont
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The impact of neurodevelopmental mutations on functional brain connectivity is poorly understood. Here the authors identify thalamo-sensorimotor dysconnectivity dimensions shared across 16p11.2 and 22q11.2 copy number variants, autism and schizophren
Externí odkaz:
https://doaj.org/article/c8046adb9f7945e59d7f1cd01bd68a9a
Autor:
Alanna Crouse, Catherine Schramm, Jean-Guillaume Emond-Rheault, Adrian Herod, Maud Kerhoas, John Rohde, Samantha Gruenheid, Irena Kukavica-Ibrulj, Brian Boyle, Celia M. T. Greenwood, Lawrence D. Goodridge, Rafael Garduno, Roger C. Levesque, Danielle Malo, France Daigle
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Salmonella comprises more than 2,600 serovars. Very few environmental and uncommon serovars have been characterized for their potential role in virulence and human infections. A complementary in vitro and in vivo systematic high-throughput a
Externí odkaz:
https://doaj.org/article/1cbd8b03b80d40479408aade43ac7b4a
Autor:
Isabelle Cremer, Catherine Sautès-Fridman, Wolf Herman Fridman, Marie Caroline Dieu-Nosjean, Mohammad Younes, Sandrine Katsahian, Jeremy Goc, Julien Cherfils-Vicini, Audrey Lupo, Marco Alifano, Catherine Schramm, Kristina Iribarren, Diane Damotte, Lucile Crozet, Saradiya Chatterjee
Toll-like receptors (TLR) recognize pathogen molecules and danger-associated signals that stimulate inflammatory processes. TLRs have been studied mainly in antigen-presenting cells, where they exert important immune regulatory functions, but they ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9359dac9dafed6fedaa8a3cee7ed7d4
https://doi.org/10.1158/0008-5472.c.6505784
https://doi.org/10.1158/0008-5472.c.6505784
Autor:
Isabelle Cremer, Catherine Sautès-Fridman, Wolf Herman Fridman, Marie Caroline Dieu-Nosjean, Mohammad Younes, Sandrine Katsahian, Jeremy Goc, Julien Cherfils-Vicini, Audrey Lupo, Marco Alifano, Catherine Schramm, Kristina Iribarren, Diane Damotte, Lucile Crozet, Saradiya Chatterjee
Supplemental Figures 1-10. Supplementary figure 1 shows that TLR7 antagonist IRS661 specifically blocks TLR7 expression by human A549 cells Supplementary figure 2 shows that TLR7 agonist induces chemoresistance in murine LL/2 cells Supplementary figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4781db693d3e56e379337e084d5ca1b0
https://doi.org/10.1158/0008-5472.22401206
https://doi.org/10.1158/0008-5472.22401206
Autor:
Ruth de Diego-Balaguer, Catherine Schramm, Isabelle Rebeix, Emmanuel Dupoux, Alexandra Durr, Alexis Brice, Perrine Charles, Laurent Cleret de Langavant, Katia Youssov, Christophe Verny, Vincent Damotte, Jean-Philippe Azulay, Cyril Goizet, Clémence Simonin, Christine Tranchant, Patrick Maison, Amandine Rialland, David Schmitz, Charlotte Jacquemot, Bertrand Fontaine, Anne-Catherine Bachoud-Lévi, French Speaking Huntington Group
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161106 (2016)
Little is known about the genetic factors modulating the progression of Huntington's disease (HD). Dopamine levels are affected in HD and modulate executive functions, the main cognitive disorder of HD. We investigated whether the Val158Met polymorph
Externí odkaz:
https://doaj.org/article/ce1eff47281e424abe8ed33bbb731069
Autor:
Gunter Schumann, Lai Jiang, Celia M. T. Greenwood, Guillaume Huguet, David J. Porteous, Antonio Ciampi, Martineau Jean-Louis, Antoine Main, Sébastien Jacquemont, Claudine Passo, Maude Auger, Catherine Schramm
Publikováno v:
Genetic Epidemiology. 44:825-840
It is challenging to estimate the phenotypic impact of the structural genome changes known as copy-number variations (CNVs), since there are many unique CNVs which are nonrecurrent, and most are too rare to be studied individually. In recent work, we