Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial

Autor: Yves Dauvilliers, Johan Verbraecken, Markku Partinen, Jan Hedner, Tarja Saaresranta, Ognian Georgiev, Rumen Tiholov, Isabelle Lecomte, Renaud Tamisier, Patrick Lévy, Catherine Scart-Gres, Jeanne-Marie Lecomte, Jean-Charles Schwartz, Jean-Louis Pépin, Valerie Attali, Patrice Bourgin, Frederic Gagnadoux, Farhad Baharloo, Soren Berg, Olli Polo, Jan Anders Hedner, Yeksel Peker, Alexander Blau, Diego Garcia Borreguero, Francisco Javier Puertas Cuesta, Georgi Belev, Yavor Ivanov, Hristo Metev, Diana Petkova, Dejan Dokic, Merita Ismajli Marku, Biserka Jokovska Kaeva, Slavko Jankovic, Ivan Kopitovic, Miodrag Vukcevic

Publikováno v: American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2020, 201 (9), pp.1135-1145. ⟨10.1164/rccm.201907-1284OC⟩
American journal of respiratory and critical care medicine

International audience; Rationale: Excessive daytime sleepiness is a common disabling symptom in obstructive sleep apnea syndrome.Objectives: To evaluate the efficacy and safety of pitolisant, a selective histamine H3 receptor antagonist with wake-pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75002b482574fd4cdea4dfe2b7ebf2c4
https://hal.umontpellier.fr/hal-03414861

P3‐002: Interest of erp biomarker in clinical development of Alzheimer's disease therapeutics

Autor: Catherine Scart Gres, Karim Bennys, Raphael Haddad, Jacques Touchon

Publikováno v: Alzheimer's & Dementia. 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50bcd20f73b8df7001fcc701fc4297c5
https://doi.org/10.1016/j.jalz.2015.06.868