Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

Autor: Marc Janier, Elsa Charignon, Catherine Savona-Baron, Jean Jacques Toulmé, Pauline Bonazza, Aref Hassan, Philippe Fernandez, Laurent Azéma, Olivier Paurelle, F. Debordeaux, David Kryza, Jacqueline Taleb, Jürgen Schulz

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Public Library of Science, 2016, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Vol 11, Iss 2, p e0149387 (2016)
PLoS ONE, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩

International audience; The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508a71d23191eec2fbe33900fe3c1507
https://hal.archives-ouvertes.fr/hal-02139130

Chronic cerebrovascular dysfunction after traumatic brain injury

Autor: Amandine, Jullienne, Andre, Obenaus, Aleksandra, Ichkova, Catherine, Savona-Baron, William J, Pearce, Jerome, Badaut

Publikováno v: Journal of neuroscience research. 94(7)

Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long-term alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form blood vessels and that are involved in maintaining their prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab45758a1ab7f042b33cc00d7139a11c
https://pubmed.ncbi.nlm.nih.gov/27117494

New insights in the biology of fibroblast growth factor-2

Autor: Andreas Bikfalvi, Sophie Javerzat, Catherine Perollet, Catherine Savona

Publikováno v: Angiogenesis. 1:155-173

Fibroblast growth factor (FGF)-2 stimulates endothelial cell proliferation and is a potent angiogenic molecule in vitro and in vivo. In this review, we have focused on recent findings that relate to the mechanism of action and function of FGF-2. FGF-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a7072ddb2d01a22c26b7224897e650
https://doi.org/10.1023/a:1018325604264

Cdc42-driven podosome formation in endothelial cells

Autor: Elisabeth Génot, Violaine Moreau, Florence Tatin, Christine Varon, Catherine Savona-Baron, Guerric Anies

Publikováno v: European journal of cell biology. 85(3-4)

Ectopic expression of a constitutive active mutant of the GTPase Cdc42 (V12Cdc42) in vascular endothelial cells triggers the dissolution of stress fibres and focal adhesion contacts and causes the repolymerisation of actin into dots. Each punctate st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e64e31aba4ac6209b834d37d2b3e1a8
https://pubmed.ncbi.nlm.nih.gov/16546575

Approximate nonlinear filtering for piecewise linear systems

Autor: Catherine Savona

Publikováno v: Systems & Control Letters. 11:327-332

We give an approximation scheme for the piecewise linear filtering problem. We prove the convergence and study the resulting algorithm on a numerical example.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1883bea2227db758de2549198b235bfb
https://doi.org/10.1016/0167-6911(88)90078-3