Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Catherine Sattler"'
Autor:
Jaren W. Landen, Niels Andreasen, Carol Cronenberger, Henrik Östlund, Martin M. Bednar, Anne Börjesson-Hanson, Pamela F. Schwartz, Catherine Sattler, Brendon Binneman
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction The safety, pharmacokinetics, and effect on peripheral and central amyloid β (Aβ) of multiple doses of ponezumab, an anti-Aβ monoclonal antibody, were characterized in subjects with mild-to-moderate Alzheimer's disease treated for 1 y
Autor:
Sharon Cohen, Qinying Zhao, Carol Cronenberger, Aaron H. Burstein, Pamela F. Schwartz, William T. Duggan, Martin M. Bednar, Kejal Kantarci, Clifford R. Jack, Brendon Binneman, Scot Styren, Jae-Hong Lee, Jaren W. Landen, Clare B. Billing, Ken J. Sprenger, Catherine Sattler
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction Multiple intravenous doses of ponezumab, an anti-amyloid antibody, were evaluated in subjects with mild-to-moderate Alzheimer's disease (AD). Methods In part A, 77 subjects were randomized to ponezumab 0.1, 0.5, or 1 mg/kg (75 treated) a
Autor:
Almasa, Bass, Anna, Plotka, Khurshid, Mridha, Catherine, Sattler, Albert M, Kim, David R, Plowchalk
Publikováno v:
Health Science Reports
Aim Prior to the discontinuation of bococizumab's clinical development, it was considered advantageous to develop an infrequent dosing regimen (eg, monthly). Therefore, we conducted a phase 1 study to evaluate the pharmacokinetics, pharmacodynamics,
Publikováno v:
Cardiovascular Therapeutics. 35:e12278
SummaryAim To characterize the single-dose pharmacokinetics (PK) and pharmacodynamics (PD) of bococizumab, a monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9), administered subcutaneously (s.c.) to the abdomen, thig
Autor:
Catherine Sattler, Aaron H. Burstein, Scot Styren, Clare B. Billing, Carol Cronenberger, Martin M. Bednar, Sharon Cohen, Jae-Hong Lee, Jaren W. Landen, Clifford R. Jack
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Brendon Binneman, Pam Schwartz, Niels Andreasen, Carol Cronenberger, Catherine Sattler, Martin M. Bednar, James Kupiec, Henrik Östlund, Anne Börjesson-Hanson, Jaren W. Landen
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
JClifford R. Jack, Denise A. Reyes, Jaren W. Landen, Catherine Sattler, Matt A. Bernstein, James T. Kupiec, Kajal Kantarci, Martin M. Bednar, Brett J. Borowski, Aaron H. Burstein
Publikováno v:
Alzheimer's & Dementia. 6