Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Catherine Sarraf"'
Publikováno v:
Cell Proliferation. 44:99-108
OBJECTIVES: Mesenchymal stem cells (MSC) are multipotent cells capable of differentiating into adipocytic, chondrocytic and osteocytic lineages on suitable stimulation. We have hypothesized that mechanical loading may influence MSC differentiation an
Autor:
Catherine Sarraf, V. Barut
Publikováno v:
Cell Proliferation. 42:657-660
Objectives: The liver is widely recognized for its ability to self‐regenerate after damage. Hepatocyte replication is the primary source of liver restoration, although hepatic stem cells (of one kind or another) may be a secondary font, only brough
Publikováno v:
Brain Pathol
In focal brain lesions, alterations in blood flow and cerebral metabolism can be detected in brain areas remote from the primary injury. The cellular consequences of this phenomenon, originally termed diaschisis, are not fully understood. Here, we re
Publikováno v:
Cell Proliferation. 38:215-221
Worldwide, and particularly in Europe, Japan and the USA, cardiovascular disease is a major killer. It can be treated using tissue or organ transplant surgery, but donor organs may be scarce. Tissue engineering is the integration of engineering princ
Publikováno v:
Tissue Engineering. 10:565-573
In the present study we have developed a multi-cue bioreactor (MCB) that is capable of delivering a range of stimuli to assist the development of a tissue-engineered construct. The MCB provides an accurate and utilizable computer-controlled pulsatile
Publikováno v:
Cell Proliferation. 36:241-254
In the industrialized world, cardiovascular disease alone is responsible for almost half of all deaths. Many of the conditions can be treated successfully with surgery, often using transplantation techniques; however, autologous vessels or human-dona
Autor:
Khurram Shehzad, Josephine C. Adams, Massimo Pignatelli, Masao Noda, Andrea Buda, Aida Jawhari, M. Jenkins, Michael J.G. Farthing, Catherine Sarraf
Publikováno v:
Scopus-Elsevier
In epithelial tissue, cell-matrix and cell-cell adhesive interactions have important roles in the normal organization and stabilization of the cell layer. The malignant conversion of epithelial cells involves alterations in the expression and functio
Autor:
Joanna Nicholls, Ragai R. Mitry, Long R. Jiao, Roman Havlik, Nagy A. Habib, Steen Lindkaer Jensen, Catherine Sarraf
Publikováno v:
Cancer Gene Therapy. 9:414-420
Background and aims: E1B-deleted virus dl1520 (ONYX-015) has been previously used in clinical trials mainly for treatment of head and neck tumors, and has been shown to have beneficial effects independent of p53 status. The main aim of this investiga
Autor:
Ahmed Abd El Latif Abu Median, Prem Seth, Ilia Isac Anis, Roman Havlik, Jack Hartwigsen, Catherine Sarraf, Nagy A. Habib, Rasha A. Abd Al Aziz, Joanna Nicholls, Hosny Salama, Ragai R. Mitry, Steen Lindkaer Jensen, Reva Bhushan
Publikováno v:
Cancer Gene Therapy. 9:254-259
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The prognosis of HCC is poor and current therapies are largely ineffective. Genetic abnormalities are commonly seen in HCC tumors particularly with inactivation of the p53 tu
Publikováno v:
Heart, Lung and Circulation. 11:142-150
Cardiovascular diseases are common in ageing communities globally. This fact is most striking in the industrialised world where the aged population makes up a large proportion of society. Elderly patients are frequently treated surgically with grafts