Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Catherine S. Nation"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. The intravascular worms acquire the nutrients necessary for their survival from host blood. Since all animals are auxotrophic for riboflavin (vi
Externí odkaz:
https://doaj.org/article/e317cf90d47b4fb0a04b7edd9fb6f283
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 568-579 (2020)
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years. We hypothesize that proteins on their host-interactive su
Externí odkaz:
https://doaj.org/article/4783348f8ee441e7ada5d28a2f1dea9c
Autor:
Luke Whitesell, Nicole Robbins, David S. Huang, Catherine A. McLellan, Tanvi Shekhar-Guturja, Emmanuelle V. LeBlanc, Catherine S. Nation, Raymond Hui, Ashley Hutchinson, Cathy Collins, Sharanya Chatterjee, Richard Trilles, Jinglin L. Xie, Damian J. Krysan, Susan Lindquist, John A. Porco, Utpal Tatu, Lauren E. Brown, Juan Pizarro, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The chaperone Hsp90 is a potential target for the development of drugs against fungal pathogens. Here the authors determine the structure of the Hsp90 nucleotide-binding domain from Candida albicans, which they use to design an inhibitor and demonstr
Externí odkaz:
https://doaj.org/article/c204109fbee74209af84981ef754b8a6
Publikováno v:
Pathogens, Vol 11, Iss 2, p 155 (2022)
Schistosomes (blood flukes) can survive in the bloodstream of their hosts for many years. We hypothesize that proteins on their host-interactive surface impinge on host biochemistry to help ensure their long-term survival. Here, we focus on a surface
Externí odkaz:
https://doaj.org/article/a323eeeef42d42c9a98552a4ce26b3d4
Autor:
Daviel Cardenas, Charity Sylvester, Bo Cao, Catherine S. Nation, Juan C. Pizarro, Hua Lu, Jessie Guidry, Edward J. Wojcik, Ben L. Kelly
Publikováno v:
mSphere, Vol 4, Iss 2 (2019)
ABSTRACT During their parasitic life cycle, through sandflies and vertebrate hosts, Leishmania parasites confront strikingly different environments, including abrupt changes in pH and temperature, to which they must rapidly adapt. These adaptations i
Externí odkaz:
https://doaj.org/article/0401eec1aa5c46ef927e63e93675b953
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0007951 (2020)
Schistosomes are parasitic blood flukes that infect >200 million people around the world. Free-swimming larval stages penetrate the skin, invade a blood vessel, and migrate through the heart and lungs to the vasculature of the liver, where maturation
Externí odkaz:
https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7
Publikováno v:
Molecular and Biochemical Parasitology. 255:111574
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-9 (2015)
Abstract Background Chagas disease is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi that represents a major public health problem in Latin America. Although the United States is defined as non-endemic for Chagas disease due t
Externí odkaz:
https://doaj.org/article/2ba5fcf1a3f0434eb611ef994fd5a953
Publikováno v:
Pathogens; Volume 11; Issue 2; Pages: 155
Schistosomes (blood flukes) can survive in the bloodstream of their hosts for many years. We hypothesize that proteins on their host-interactive surface impinge on host biochemistry to help ensure their long-term survival. Here, we focus on a surface
Publikováno v:
The Biochemical journal. 479(11)
Infection with schistosomes (blood flukes) can result in the debilitating disease schistosomiasis. These parasites survive in their host for many years, and we hypothesize that proteins on their tegumental surface, interacting with the host microenvi