Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Catherine Pale-Grosdemange"'
Autor:
Catherine Pale-Grosdemange, Luisa Maria Lois, Michel Rohmer, Albert Boronat, Lionel Charon, Narciso Campos, Jean-François Hoeffler
Publikováno v:
Biochemical Journal. 346:737-742
Escherichia coli synthesizes its isoprenoids via the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. The MC4100dxs::CAT strain, defective in deoxyxylulose-5-phosphate synthase, which is the first enzyme in this metabolic rou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6ac5e0e36cc7c3169c808c6e0fa400
https://doi.org/10.1042/bj3460737
https://doi.org/10.1042/bj3460737
Publikováno v:
Tetrahedron Letters. 40:8369-8373
2- C -Methyl- d -erythritol 4-phosphate is a key intermediate in the mevalonate independent pathway for isoprenoid biosynthesis. In order to investigate the fate of the protons in this metabolic route, [3,5,5,5- 2 H 4 ]-2- C -methyl- d -erythritol wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee426aeee00926cc95290a619e50a7d2
https://doi.org/10.1016/s0040-4039(99)01769-4
https://doi.org/10.1016/s0040-4039(99)01769-4
Publikováno v:
Tetrahedron Letters. 40:7231-7234
Zymomonas mobilis synthesizes triterpenoids of the hopane series via the methylerythritol phosphate (MEP) pathway. Owing to the peculiar metabolic pathways in this bacterium, [1-2H]glucose is the appropriate substrate for generating in vivo deuterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950cd4e74c76d57c0cfd9b43880d2a46
https://doi.org/10.1016/s0040-4039(99)01531-2
https://doi.org/10.1016/s0040-4039(99)01531-2
Publikováno v:
Tetrahedron Letters. 40:6009-6012
Mutagenesis of Tyr420 to Ala in the catalytic cavity of squalene-hopene cyclase of Alicyclobacillus acidocaldarius resulted in an altered product spectrum. Besides hopene and diplopterol, this mutant produced significant amounts of the bicyclic α- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7571750a71cfbc192367dcf1d35ddbc5
https://doi.org/10.1016/s0040-4039(99)01248-4
https://doi.org/10.1016/s0040-4039(99)01248-4
Autor:
Michel Rohmer, Karl Ulrich Wendt, Karl Poralla, Thorsten Merkofer, Catherine Pale-Grosdemange
Publikováno v:
Tetrahedron Letters. 40:2121-2124
Amino acid residues lining the catalytic cavity of squalene-hopene cyclase of Alicyclobacillus acidocaldarius have been mutated. Alterations of His451 to Ala and Trp489 to Ala resulted in reduced enzymatic activity, while the product patterns were id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1576bb1621f6f34be9fdec10882ccca
https://doi.org/10.1016/s0040-4039(99)00145-8
https://doi.org/10.1016/s0040-4039(99)00145-8
Publikováno v:
Angewandte Chemie International Edition. 37:2237-2240
Tetracyclic triterpenes (for example, 3) are formed as minor products of the cyclization of squalene (1) by squalene/hopene cyclase; they have also been found in vivo. The identification of these side products offers new insight into the complex bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94dae95ea6d4b28639043e9bf6e71dc9
https://doi.org/10.1002/(sici)1521-3773(19980904)37:16<2237::aid-anie2237>3.0.co
https://doi.org/10.1002/(sici)1521-3773(19980904)37:16<2237::aid-anie2237>3.0.co
Publikováno v:
Angewandte Chemie. 110:2355-2358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dca2222f55d0debb31872e0e65e5d84
https://doi.org/10.1002/(sici)1521-3757(19980817)110:16<2355::aid-ange2355>3.0.co
https://doi.org/10.1002/(sici)1521-3757(19980817)110:16<2355::aid-ange2355>3.0.co
Autor:
Catherine Pale-Grosdemange, Michel Rohmer, Knut Danielsen, Luisa Maria Lois, Albert Boronat, Narciso Campos, Lionel Charon, Surya Rosa Putra
Publikováno v:
Tetrahedron Letters. 39:6185-6188
Cell-free systems from the bacteria Escherichia coli and Klebsiella planticola that were incubated with 13 C labeled pyruvate and D-glyceraldehyde synthesized 5-hydroxypentane-2,3-dione (laurencione) along with 1-deoxy-D- threo -pentulose (1-deoxy-D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5243e186c9a7d93c73878271879989
https://doi.org/10.1016/s0040-4039(98)01301-x
https://doi.org/10.1016/s0040-4039(98)01301-x
Publikováno v:
Tetrahedron Letters. 38:4769-4772
According to incorporations of 13 labelled glucose, 2-C-methyl-d-erythritol was most likely synthesized by Corynebacterium ammoniagenes from glyceraldehyde 3-phosphate and from pyruvate via a condensation and a rearrangement. The observed labelling p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dec2d2f190d970cb831b109e24d7af0
https://doi.org/10.1016/s0040-4039(97)01045-9
https://doi.org/10.1016/s0040-4039(97)01045-9
Autor:
Albert Boronat, Michel Rohmer, Narciso Campos, Knut Danielsen, Surya Rosa Putra, Lionel Charon, Catherine Pale-Grosdemange, Luisa Maria Lois
Publikováno v:
ChemInform. 29
Cell-free systems from the bacteria Escherichia coli and Klebsiella planticola that were incubated with 13 C labeled pyruvate and D-glyceraldehyde synthesized 5-hydroxypentane-2,3-dione (laurencione) along with 1-deoxy-D- threo -pentulose (1-deoxy-D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e9ab361db86cbc2af1fdd188f49757
https://doi.org/10.1002/chin.199845214
https://doi.org/10.1002/chin.199845214