Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Catherine Overed-Sayer"'
Autor:
Anindya Roy, Lei Shi, Ashley Chang, Xianchi Dong, Andres Fernandez, John C. Kraft, Jing Li, Viet Q. Le, Rebecca Viazzo Winegar, Gerald Maxwell Cherf, Dean Slocum, P. Daniel Poulson, Garrett E. Casper, Mary L. Vallecillo-Zúniga, Jonard Corpuz Valdoz, Marcos C. Miranda, Hua Bai, Yakov Kipnis, Audrey Olshefsky, Tanu Priya, Lauren Carter, Rashmi Ravichandran, Cameron M. Chow, Max R. Johnson, Suna Cheng, McKaela Smith, Catherine Overed-Sayer, Donna K. Finch, David Lowe, Asim K. Bera, Gustavo Matute-Bello, Timothy P. Birkland, Frank DiMaio, Ganesh Raghu, Jennifer R. Cochran, Lance J. Stewart, Melody G. Campbell, Pam M. Van Ry, Timothy Springer, David Baker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The RGD (Arg-Gly-Asp)-binding integrins αvβ6 and αvβ8 are clinically validated cancer and fibrosis targets of considerable therapeutic importance. Compounds that can discriminate between homologous αvβ6 and αvβ8 and other RGD integri
Externí odkaz:
https://doaj.org/article/e3c311aafe5446188603fdc35eee2511
Autor:
Susan Monkley, Catherine Overed-Sayer, Helen Parfrey, Doris Rassl, Damian Crowther, Leire Escudero-Ibarz, Nicola Davis, Alan Carruthers, Richard Berks, Marisa Coetzee, Ewa Kolosionek, Maria Karlsson, Leia R. Griffin, Maryam Clausen, Graham Belfield, Cory M. Hogaboam, Lynne A. Murray
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The unfolded protein response (UPR) is a direct consequence of cellular endoplasmic reticulum (ER) stress and a key disease driving mechanism in IPF. The resolution of the UPR is directed by PPP1R15A (GADD34) and leads to the restoration of
Externí odkaz:
https://doaj.org/article/140262651e644238bf169dc86b4b8869
Autor:
Agata Radwanska, Christopher Travis Cottage, Antonio Piras, Catherine Overed-Sayer, Carina Sihlbom, Ramachandramouli Budida, Catherine Wrench, Jane Connor, Susan Monkley, Petra Hazon, Holger Schluter, Matthew J. Thomas, Cory M. Hogaboam, Lynne A. Murray
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unmet medical need. It is characterized by formation of scar tissue leading to a progressive and irreversible decline in lung function. IPF is associated with repeated injury, which may alte
Externí odkaz:
https://doaj.org/article/893273a899624c7f8501668b4c65941b
Autor:
Ana Camelo, Guglielmo Rosignoli, Yoichiro Ohne, Ross A. Stewart, Catherine Overed-Sayer, Matthew A. Sleeman, Richard D. May
Publikováno v:
Blood Advances, Vol 1, Iss 10, Pp 577-589 (2017)
Abstract: Innate lymphoid cells (ILCs) represent a distinct branch of the lymphoid lineage composed of 3 major subpopulations: ILC1, ILC2, and ILC3. ILCs are mainly described as tissue-resident cells but can be detected at low levels in human blood.
Externí odkaz:
https://doaj.org/article/d2bd093d25c0440a9375db587595ccd6
Autor:
Victoria Ptasinski, Susan J. Monkley, Karolina Öst, Markus Tammia, Catherine Overed-Sayer, Petra Hazon, Darcy E. Wagner, Lynne A. Murray
Repeated injury of the lung epithelium is proposed to be a main driver of idiopathic pulmonary fibrosis (IPF). However, none of the available therapies target the epithelium and there is a limited amount of human models of fibrotic epithelial damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f01dfdb4ac23bbdb138c14b2d754519e
https://doi.org/10.1101/2022.06.15.496102
https://doi.org/10.1101/2022.06.15.496102
Autor:
Victoria Ptasinski, Susan J Monkley, Karolina Öst, Markus Tammia, Hani N Alsafadi, Catherine Overed-Sayer, Petra Hazon, Darcy E Wagner, Lynne A Murray
Publikováno v:
Life Science Alliance. 6:e202201853
Repeated injury of the lung epithelium is proposed to be the main driver of idiopathic pulmonary fibrosis (IPF). However, available therapies do not specifically target the epithelium and human models of fibrotic epithelial damage with suitability fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77aeff0a9ad517575a54ca28ff964fe4
https://doi.org/10.26508/lsa.202201853
https://doi.org/10.26508/lsa.202201853