Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Catherine Olesch"'
Autor:
Rienk Offringa, Ralf Lesche, Iris Oezen, Michael Platten, Daniel Baumann, Christiane A Opitz, Ahmed Sadik, Catherine Olesch, Frederik Cichon, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Katharina Sahm, Nirmeen Elmadany, Christina Kober, Julian Roewe, Lars Roese, Benjamin Bader, Mátyás Gorjánácz, Helge Gottfried Roider, Gabriele Leder, Horst Irlbacher, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Rafael Carretero, Hilmar Weinmann, Ingo V Hartung, Bertolt Kreft, Ilona Gutcher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background The metabolism of tryptophan to kynurenines (KYN) by indoleamine-2,3-dioxygenase or tryptophan-2,3-dioxygenase is a key pathway of constitutive and adaptive tumor immune resistance. The immunosuppressive effects of KYN in the tumor microen
Externí odkaz:
https://doaj.org/article/bc1e59d7b2b148a6869f255df5b9d454
Autor:
Rienk Offringa, Catherine Olesch, Frederik Cichon, Mareike Grees, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Michael Erkelenz, Thi Thanh Uyen Nguyen, Ulf Boemer, Judith Günther, Marc Kunze, Kirstin Petersen, Dennis Kirchhoff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/07ab2b5c8fd7488eb234fe061e205932
Autor:
Catherine Olesch, David Brunn, Öznur Aktay-Cetin, Evelyn Sirait-Fischer, Soni Savai Pullamsetti, Friedrich Grimminger, Werner Seeger, Bernhard Brüne, Andreas Weigert, Rajkumar Savai
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The lung tumor microenvironment plays a critical role in the tumorigenesis and metastasis of lung cancer, resulting from the crosstalk between cancer cells and microenvironmental cells. Therefore, comprehensive identification and characterization of
Externí odkaz:
https://doaj.org/article/fb6962e73c2d4b638e8de1df05b857b2
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1289 (2022)
The sphingolipid sphingosine-1-phosphate (S1P) promotes tumor development through a variety of mechanisms including promoting proliferation, survival, and migration of cancer cells. Moreover, S1P emerged as an important regulator of tumor microenviro
Externí odkaz:
https://doaj.org/article/b6e831ceb0a64dbd9e3ad52fe654ee48
Autor:
Evelyn Sirait-Fischer, Catherine Olesch, Annika F. Fink, Matthias Berkefeld, Arnaud Huard, Tobias Schmid, Kazuhiko Takeda, Bernhard Brüne, Andreas Weigert
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Despite the success of immune checkpoint blockade in cancer, the number of patients that benefit from this revolutionary treatment option remains low. Therefore, efforts are being undertaken to sensitize tumors for immune checkpoint blockade, which i
Externí odkaz:
https://doaj.org/article/ab246b617c8f4cf9a5fa4b4d678e21b4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The sphingolipid sphingosine-1-phosphate (S1P) is produced by sphingosine kinases to either signal through intracellular targets or to activate a family of specific G-protein-coupled receptors (S1PR). S1P levels are usually low in peripheral tissues
Externí odkaz:
https://doaj.org/article/c4a967ccc67e482f83e5ee233ba2d94b
Autor:
Franziska Moll, Maria Walter, Flávia Rezende, Valeska Helfinger, Estefania Vasconez, Tiago De Oliveira, Florian R. Greten, Catherine Olesch, Andreas Weigert, Heinfried H. Radeke, Katrin Schröder
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
AimReactive oxygen species (ROS) produced by enzymes of the NADPH oxidase family serve as second messengers for cellular signaling. Processes such as differentiation and proliferation are regulated by NADPH oxidases. In the intestine, due to the exce
Externí odkaz:
https://doaj.org/article/147fd63112754e83979e52a016782146
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
The sphingolipid sphingosine-1-phosphate (S1P) emerges as an important regulator of immunity, mainly by signaling through a family of five specific G protein-coupled receptors (S1PR1–5). While S1P signaling generally has the potential to affect not
Externí odkaz:
https://doaj.org/article/974fef0abfe14a009cc05d2a877d4d01
Autor:
Dominik C. Fuhrmann, Catherine Olesch, Nina Kurrle, Frank Schnütgen, Sven Zukunft, Ingrid Fleming, Bernhard Brüne
Publikováno v:
Cells, Vol 8, Iss 2, p 172 (2019)
Hypoxia poses a stress to cells and decreases mitochondrial respiration, in part by electron transport chain (ETC) complex reorganization. While metabolism under acute hypoxia is well characterized, alterations under chronic hypoxia largely remain un
Externí odkaz:
https://doaj.org/article/add5e14c188f4f08a593ba890f6276a4
Autor:
G-Andre Banat, Aleksandra Tretyn, Soni Savai Pullamsetti, Jochen Wilhelm, Andreas Weigert, Catherine Olesch, Katharina Ebel, Thorsten Stiewe, Friedrich Grimminger, Werner Seeger, Ludger Fink, Rajkumar Savai
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139073 (2015)
Recent studies indicate that the abnormal microenvironment of tumors may play a critical role in carcinogenesis, including lung cancer. We comprehensively assessed the number of stromal cells, especially immune/inflammatory cells, in lung cancer and
Externí odkaz:
https://doaj.org/article/1c3b10634286491f8fda4890613bf45c