Specificity of the T Cell Response to Protein Biopharmaceuticals

Autor: Sylvain Meunier, Marie de Bourayne, Moustafa Hamze, Aurélien Azam, Evelyne Correia, Catherine Menier, Bernard Maillère

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

The anti-drug antibody (ADA) response is an undesired humoral response raised against protein biopharmaceuticals (BPs) which can dramatically disturb their therapeutic properties. One particularity of the ADA response resides in the nature of the imm

Externí odkaz: https://doaj.org/article/436994c0f3c5482aa848aeadb28b3c1d

Specificity of the T Cell Response to Protein Biopharmaceuticals

Autor: Moustafa Hamze, Aurélien Azam, Marie de Bourayne, Catherine Menier, Evelyne Correia, Sylvain Meunier, Bernard Maillere

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, 11, pp.1-14. ⟨10.3389/fimmu.2020.01550⟩
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, 2020, 11, pp.1-14. ⟨10.3389/fimmu.2020.01550⟩

International audience; The anti-drug antibody (ADA) response is an undesired humoral response raised against protein biopharmaceuticals (BPs) which can dramatically disturb their therapeutic properties. One particularity of the ADA response resides

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432b693d9d65262534bd8461992244d2
http://europepmc.org/articles/PMC7387651

HLA-G1 and HLA-G5 active dimers are present in malignant cells and effusions: The influence of the tumor microenvironment

Autor: Benoit Favier, Roman Rouzier, Nathalie Rouas-Freiss, Catherine Menier, Sonia Zilberman, Béatrice Riteau, Chantal Schenowitz, Sophie Agaugué, Edgardo D. Carosella

Publikováno v: European Journal of Immunology. 42:1599-1608

Dimers of the nonclassical HLA-G class I molecule have recently been shown to be active structures that mediate inhibition of NK-cell cytotoxic activity through interaction with the immunoglobulin-like transcript (ILT)-2 inhibitory receptor. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab70d5081cff62ed7f064aec83c8ef1a
https://doi.org/10.1002/eji.201141761

Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis

Autor: Nathalie Rouas-Freiss, Edgardo D. Carosella, Catherine Menier, Michèle Rabreau, Magali Le Discorde, Jean-Claude Challier

Publikováno v: Blood. 104:3153-3160

The initial steps of primitive hematopoiesis and endothelial vascular formation in the human embryo remain to be defined. Here, we report the identification of a novel marker, namely the nonclassical HLA-G class I molecule, which targets both primiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61fb5a05153700c40224a9d4c9e83cc
https://doi.org/10.1182/blood-2004-03-0809

Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation

Autor: Catherine Menier, Antoine Durrbach, Nathalie Rouas-Freiss, Didier Samuel, Edgardo D. Carosella, Jean Dausset, Caroline Créput, Bernard Charpentier, Catherine Guettier

Publikováno v: Journal of Hepatology. 39:587-594

Background/Aims : Liver allograft is known to protect simultaneously transplanted organs from acute rejection. We have reported that only 6% of combined liver-kidney recipients, versus 32.5% of kidney recipients, develop kidney graft acute rejection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18de9d28d631efccf8d76b8fe7505c7
https://doi.org/10.1016/s0168-8278(03)00354-4