Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Catherine M. Watson"'
Autor:
Roger R. Reddel, Catherine M. Watson, Hilda A. Pickett, Patrick P.L. Tam, Jane R. Noble, Axel A. Neumann
Publikováno v:
Genes & Development. 27:18-23
Some cancers use alternative lengthening of telomeres (ALT), a mechanism whereby new telomeric DNA is synthesized from a DNA template. To determine whether normal mammalian tissues have ALT activity, we generated a mouse strain containing a DNA tag i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a116b889b8bd8f3f22f07ab707329d
https://doi.org/10.1101/gad.205062.112
https://doi.org/10.1101/gad.205062.112
Autor:
John Christodoulou, Melinda Hayward, Patrick P.L. Tam, Tania Radziewic, Catherine M. Watson, Hooshang Lahooti, Gregory J. Pelka
Publikováno v:
Brain. 129:887-898
Rett syndrome (RTT) is a debilitating neurological condition associated with mutations in the X-linked MECP2 gene, where apparently normal development is seen prior to the onset of cognitive and motor deterioration at 6-18 months of life. A targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8629490b5ecfd312a99b1a61ea41089e
https://doi.org/10.1093/brain/awl022
https://doi.org/10.1093/brain/awl022
Autor:
Catherine M. Watson, Mona D. Shahbazian, Tatiana Radziewic, Patrick P.L. Tam, Gregory J. Pelka, Sarah L. Williamson, John Christodoulou
Publikováno v:
Human Molecular Genetics. 14:1851-1861
Rett syndrome (RTT) is an X-linked disorder caused by mutations in the methyl CpG binding protein 2 (MECP2) gene. The pattern of X-chromosome inactivation (XCI) is thought to play a role in phenotypic severity. In the present study, patterns of XCI w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cbf48a917f67a0eefdd7b96d4e07cf
https://doi.org/10.1093/hmg/ddi191
https://doi.org/10.1093/hmg/ddi191
Autor:
Julie Evans, John Christodoulou, Gregory J. Pelka, Patrick P.L. Tam, Carolyn Ellaway, Catherine M. Watson, Linda S. Weaving, Angus John Clarke, Olivia L. D. McKenzie, Hayley Archer, Hooshang Lahooti, Sarah L. Williamson, Jozef Gecz, Bruce Bennetts, Kathie L. Friend, Helen Leonard
Publikováno v:
The American Journal of Human Genetics. 75(6):1079-1093
Rett syndrome (RTT) is a severe neurodevelopmental disorder caused, in most classic cases, by mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2). A large degree of phenotypic variation has been observed in patients with RTT, both tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd2ca3eb7493d50979da8dbc5153943
Autor:
Elizabeth M. Deane, Lauren J. Young, Katarzyna B. Miska, Gavan A. Harrison, Catherine M. Watson, Robert D. Miller
Publikováno v:
Cytokine. 21:105-119
Sequence data for type I interferons (IFNs) have previously only been available for birds and eutherian ('placental') mammals, but not for the other two groups of extant mammals, the marsupials and monotremes. This has left a large gap in our knowled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6fec3f391e681ddb188496b66ac9b6
https://doi.org/10.1016/s1043-4666(03)00029-2
https://doi.org/10.1016/s1043-4666(03)00029-2
Autor:
Catherine M. Watson, Desmond W. Cooper, Robert T. Gemmell, David A. Loebel, R. Leon Hughes, P. G. Johnston
Publikováno v:
Molecular Reproduction and Development. 57:127-134
In marsupials testis determination requires the presence of a Y chromosome. The sex determining region on the Y gene (SRY) is necessary for testicular development in eutherians and it is assumed to play a similar role in marsupials. Relatively few st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d71aefc2757880e71f2c3a97d4608d11
https://doi.org/10.1002/1098-2795(200010)57:2<127::aid-mrd3>3.0.co
https://doi.org/10.1002/1098-2795(200010)57:2<127::aid-mrd3>3.0.co
Autor:
Gabriel A. Quinlan, Monica L. Gordon, Karin S. Sturm, Tania Radziewic, Paul A. Trainor, Maala Parameswaran, Patrick P.L. Tam, Catherine M. Watson, Gregory J. Pelka, Sheila X. Zhou
Publikováno v:
METHODS IN MOLECULAR BIOLOGY™ ISBN: 9781588294319
Cell lineage analyses trace the hierarchy of cell types derived from a progenitor population. Critical to these analyses is the ability to track reliably all or defined subsets of the clonal descendants of the progenitor population. This necessitates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0748142dae93e0ddf6ebefb164d66c
https://pubmed.ncbi.nlm.nih.gov/19030795
https://pubmed.ncbi.nlm.nih.gov/19030795
Publikováno v:
Genomics. 85(4)
Four different transcripts of the Mecp2 gene can be distinguished by the length of the 3' untranslated region generated by usage of alternative polyadenylation sites. In situ hybridization analyses encompassing embryonic to 20-week postnatal age show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd43d1a5ba4476718d7c0411ba97abb
https://pubmed.ncbi.nlm.nih.gov/15780747
https://pubmed.ncbi.nlm.nih.gov/15780747
Publikováno v:
Developmental biology. 264(1)
The use of embryonic stem (ES) cells for generating healthy tissues has the potential to revolutionize therapies for human disease or injury, for which there are currently no effective treatments. Strategies for manipulating stem cell differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0589079f488d5cf8b2b93ed61e943e24
https://pubmed.ncbi.nlm.nih.gov/14623228
https://pubmed.ncbi.nlm.nih.gov/14623228
Autor:
Catherine M. Watson, Patrick P.L. Tam
Publikováno v:
Cell structure and function. 26(3)
During the peri-implantation development of the mouse embryo from the blastocyst through gastrulation, Pou5f1 (OCT-4) down-regulation is closely linked to the initial step of lineage allocation to extraembryonic and embryonic somatic tissues. Subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0007873aaae3f7849a7adaa0996a732f
https://pubmed.ncbi.nlm.nih.gov/11565804
https://pubmed.ncbi.nlm.nih.gov/11565804