Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Catherine M. Stein"'
Autor:
E. Ricky Chan, Penelope Benchek, Gabrielle Miller, Kim Brustoski, Ashleigh Schaffer, Barbara Truitt, Jessica Tag, Lisa Freebairn, Barbara A. Lewis, Catherine M. Stein, Sudha K. Iyengar
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Childhood apraxia of speech (CAS) is a severe and rare form of speech sound disorder (SSD). CAS is typically sporadic, but may segregate in families with broader speech and language deficits. We hypothesize that genetic changes may be involv
Externí odkaz:
https://doaj.org/article/400fb69bb6e74c66b15212f4f8ec8dbd
Autor:
Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Felicia K. Nguyen, Monica Campo, Penelope Benchek, Catherine M. Stein, Tomas Vaisar, Harriet Mayanja-Kizza, W. Henry Boom, Thomas R. Hawn
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT Mycobacterium tuberculosis (Mtb) exposure leads to a range of outcomes including clearance, latent TB infection (LTBI), and pulmonary tuberculosis (TB). Some heavily exposed individuals resist tuberculin skin test (TST) and interferon-gamma
Externí odkaz:
https://doaj.org/article/b5310dd7b1304cafaf2e9ec3f37e81f3
Autor:
Hyejeong Hong, Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Penelope Benchek, Harriet Mayanja-Kizza, W. Henry Boom, Catherine M. Stein, Thomas R. Hawn
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe heterogeneity of outcomes after Mycobacterium tuberculosis (Mtb) exposure is a conundrum associated with millennia of host-pathogen co-evolution. We hypothesized that human myeloid cells contain genetically encoded, Mtb-specific respo
Externí odkaz:
https://doaj.org/article/a0aa5ef9a6bd430e8e6bb1cdca54ddd9
Autor:
Jesús Gutierrez, Mary Nsereko, LaShaunda L. Malone, Harriet Mayanja-Kizza, Hussein Kisingo, W. Henry Boom, Charles M. Bark, Catherine M. Stein
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 4, p 81 (2024)
Reductions in tuberculosis (TB) incidence require identification of individuals at high risk of developing active disease, such as those with recent Mycobacterium tuberculosis (Mtb) infection. Using a prospective household contact (HHC) study in Kamp
Externí odkaz:
https://doaj.org/article/389539a8c8af4166b36ecc693c1d7ae5
Autor:
Leela R.L. Davies, Malisa T. Smith, Deniz Cizmeci, Stephanie Fischinger, Jessica Shih-Lu Lee, Lenette L. Lu, Erik D. Layton, Alison D. Grant, Katherine Fielding, Catherine M. Stein, W. Henry Boom, Thomas R. Hawn, Sarah M. Fortune, Robert S. Wallis, Gavin J. Churchyard, Galit Alter, Chetan Seshadri
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104678- (2023)
Summary: Background: The prevalence of tuberculosis among men who work in the gold mines of South Africa is among the highest in the world, but a fraction of miners demonstrate consistently negative results upon tuberculin skin test (TST) and IFN-γ
Externí odkaz:
https://doaj.org/article/0c58ca4c3fba49d19ebee7d80aaf7eba
Autor:
Penelope Benchek, Robert P. Igo, Heather Voss-Hoynes, Yvonne Wren, Gabrielle Miller, Barbara Truitt, Wen Zhang, Michael Osterman, Lisa Freebairn, Jessica Tag, H. Gerry Taylor, E. Ricky Chan, Panos Roussos, Barbara Lewis, Catherine M. Stein, Sudha K. Iyengar
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Speech sound disorders (SSD) manifest as difficulties in phonological memory and awareness, oral motor function, language, vocabulary, reading, and spelling. Families enriched for SSD are rare, and typically display a cluster of deficits. We
Externí odkaz:
https://doaj.org/article/d38c6d042b0447528a6e9bfb3a1cde4b
Autor:
Jason D. Simmons, Kimberly A. Dill-McFarland, Catherine M. Stein, Phu T. Van, Violet Chihota, Thobani Ntshiqa, Pholo Maenetje, Glenna J. Peterson, Penelope Benchek, Mary Nsereko, Kavindhran Velen, Katherine L. Fielding, Alison D. Grant, Raphael Gottardo, Harriet Mayanja-Kizza, Robert S. Wallis, Gavin Churchyard, W. Henry Boom, Thomas R. Hawn
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Heavy exposure to Mycobacterium tuberculosis, the etiologic agent of tuberculosis (TB) and among the top infectious killers worldwide, results in infection that is cleared, contained, or progresses to disease. Some heavily exposed tuberculos
Externí odkaz:
https://doaj.org/article/252d3100c4d740a68e03d104c295cd58
Feature-driven classification reveals potential comorbid subtypes within childhood apraxia of speech
Autor:
Catherine M. Stein, Penelope Benchek, Gabrielle Miller, Noémi B. Hall, Dhanya Menon, Lisa Freebairn, Jessica Tag, Jennell Vick, H. Gerry Taylor, Barbara A. Lewis, Sudha K. Iyengar
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Childhood apraxia of speech (CAS) is a neurodevelopmental disorder with heterogeneous communication and other comorbid manifestations. While previous studies have characterized speech deficits associated with CAS, few studies have
Externí odkaz:
https://doaj.org/article/cf9f5dc2997d4a37bb8c4b4dcf828ee8
Autor:
Michael L McHenry, Penelope Benchek, LaShaunda Malone, Mary Nsereko, Harriet Mayanja-Kizza, W. Henry Boom, Scott M. Williams, Thomas R. Hawn, Catherine M. Stein
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103727- (2021)
Background: Pulmonary tuberculosis (TB) is one of the most deadly pathogens on earth. However, the majority of people have resistance to active disease. Further, some individuals, termed resisters (RSTRs), do not develop traditional latent tuberculos
Externí odkaz:
https://doaj.org/article/af742d77d40a4558afb26f88a4302866
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tuberculosis (TB) remains a worldwide problem. Despite the high disease rate, not all who are infected with Mycobacterium Tuberculosis (Mtb) develop disease. Interferon-γ (IFN-γ) specific T cell immune assays such as Quantiferon and Elispot, as wel
Externí odkaz:
https://doaj.org/article/b5befba357c145548f2743dcc8bf06b5